4 research outputs found
Structural formulae of Artemisinin and synthetic derivatives belonging to the first category AJ.
<p>Structural formulae of Artemisinin and synthetic derivatives belonging to the first category AJ.</p
Structural formulae of Artemisinin and synthetic derivatives belonging to the second category TVN.
<p>Structural formulae of Artemisinin and synthetic derivatives belonging to the second category TVN.</p
<i>In vitro</i> anti-HCV activity of Artemisinin and its selected analogues on the replication of infectious HCVcc as measured by means of qRT-PCR (n = 4).
<p>a) ART; b) TVN4; c) AJ-002 and d) AJ-004. Bars indicate the HCV RNA level as compared to control (%) and lines represent the cell growth as compared to untreated controls (%).</p
Effect of ART and derivatives on Huh 5-2 HCV replicon replication.
<p>∶ 50% effective concentration, CC50∶ 50% cytostatic concentration. Data obtained from the measurement of the firefly luciferase activity, and are mean values ± SD for four independent experiments (expressed in µM).<sup></sup> EC50</p><p>µM, Hemin inhibits HCV replicon replication by 30%.<sup></sup> Values between brackets indicate fold-change. At 5 </p