505 research outputs found

    <i>Vaccinia virus</i>, 33 strains, 17562 SNPs (increased).

    No full text
    <p><i>Vaccinia virus</i>, 33 strains, 17562 SNPs (increased).</p

    Algorithm GetBlock.

    No full text
    <p>Algorithm GetBlock.</p

    Simple Branched Sulfur–Olefins as Chiral Ligands for Rh-Catalyzed Asymmetric Arylation of Cyclic Ketimines: Highly Enantioselective Construction of Tetrasubstituted Carbon Stereocenters

    No full text
    New, simple, sulfinamide-based branched olefin ligands have been developed and successfully used in Rh-catalyzed asymmetric arylations of cyclic ketimines, providing efficient and highly enantioselective access to valuable benzosultams and benzosulfamidates containing a stereogenic quaternary carbon center. This is the first example of applying a sulfur–olefin ligand in catalytic asymmetric addition of imines

    Evolutionary tree of <i>Burkholderia pseudomallei</i>.

    No full text
    <p>The internal nodes are labeled by the number of events, m for mutation, e for error, and x for HRE.</p

    Summary of results from HREfinder and kSNP.

    No full text
    <p>Core SNPs are loci present in all the genomes. Homoplastic SNPs are those that are not consistent with the pattern of inheritance in the predicted SNP-based phylogeny.</p

    Rhodium-Catalyzed Asymmetric Arylation of Cyclic <i>N</i>‑Sulfonyl Aryl Alkyl Ketimines: Efficient Access to Highly Enantioenriched α‑Tertiary Amines

    No full text
    A simple catalyst system of Rh­(I)/sulfur-olefin with exceptional catalytic performance has been developed for the highly enantioselective arylation of cyclic <i>N</i>-sulfonyl aryl alkyl ketimines with arylboroxines/arylboronic acids. Optically active α-arylalkyl-substituted benzosultams and benzosulfamidates which are generally difficult to obtain were easily prepared with excellent stereocontrol (up to 99.9% ee). The synthetic utility of the approach was demonstrated by the facile construction of NMDA antagonist FR115427 and benzoxazinone derivatives. This protocol offers new opportunities for the efficient synthesis of diverse chiral α-tertiary amines

    An example of detection of HREs.

    No full text
    <p>The SNPs on node 6 are better explained by an HRE from node 2 than inheritance from node 5 with three mutations. The first 2 A’s and last A do not represent SNPs, but merely serve as sequence context for the SNPs in between.</p

    <i>Burkholderia mallei</i>, 11 strains, 3659 SNPs (increased).

    No full text
    <p><i>Burkholderia mallei</i>, 11 strains, 3659 SNPs (increased).</p
    • …
    corecore