14 research outputs found

    Demographic characteristics and respiratory history of the cohort.

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    <p><sup>§</sup> scored according to a modified Bhalla scale as previously reported [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0129517#pone.0129517.ref013" target="_blank">13</a>].</p><p>Demographic characteristics and respiratory history of the cohort.</p

    Adaptive (72 hour) cytokine production to NTHi.

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    <p>a) In vitro cytokine production by HC (open circles) and CSLD (filled circles) PBMC following 72 hour challenge with NTHi. Delta concentration (NTHi challenge minus nil challenge) with median and IQR. b) Trajectory of adaptive (72 hour) IFN-γ production to NTHi with age. In vitro cytokine production by HC (open circles) and CSLD (filled circles) PBMC following 72 hour challenge with NTHi. Median (delta) concentration, pg/ml.</p

    Innate (24 hour) cytokine production.

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    <p>In vitro cytokine production by HC (open circles) and CSLD (filled circles) PBMC following 24 hour challenge with NTHi. Delta concentration (NTHi challenge minus nil challenge) with median and IQR.</p

    Adaptive (72 hour) cytokine production to PHA.

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    <p>In vitro cytokine production by HC (open symbols) and CSLD (filled symbols) PBMC following 72 hour challenge with the non-specific mitogen PHA. Delta concentration (NTHi challenge minus nil challenge) with median and IQR.</p

    Serum IgG1 and IgG4 to outer membrane proteins P4 and P6.

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    <p>HC (open circles) and CSLD (filled circles). Concentration with median and inter-quartile range.</p
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