FishInspector v1.02 - Annotation of features from zebrafish embryo images

The software FishInspector allows annotation of features in images of zebrafish. The recent version requires images of a lateral position. It is important that the position is precise since deviation may confound with feature annotations. Images from any source can be used. However, depending on the image properties parameters may have to be adjusted. Furthermore, images obtained with normal microscope and not using an automated position system with embryos in glass capillary require conversion using a KNIME workflow (the workflow is provided as well). As a result of the analysis the softare provides JSON files that contain the coordinates of the features. Coordinates are provided for eye size, fish contour, notochord curvature, otolith eye distance, yolk sac, pericard and swimbladder. Furthermore, the intensity of pigmentation is calculated for the notochord area. Additional features can be manually annotated. It is the aim of the software to provide the coordinates, which may then be analysed subsequently to identify and quantify changes in the morphology of zebrafish embryos.</p

Media 1: Dynamic cross-waveguide optical switching with a nonlinear photonic band-gap structure

Originally published in Optics Express on 06 July 1998 (oe-3-1-28

The Sodium Siloxides (<i>t</i>Bu₃SiONa)₄ and (<i>t</i>Bu₂PhSiONa)₄: Synthesis and X-ray Crystal Structure Analysis

The sodium siloxides (tBu3SiONa)4 and (tBu2PhSiONa)4 can be synthesized almost quantitatively from the reaction of the sodium silanides tBu3SiNa and tBu2PhSiNa with N2O in tetrahydrofuran at −78 °C. (tBu3SiONa)4 and (tBu2PhSiONa)4 are the first structurally characterized sodium siloxides featuring a heterocubane framework in the solid state. X-ray quality crystals of the supersilanol, tBu3SiOH (monoclinic, C2/c), were obtained from the thermolysis of tBu3SiNaN−NNSitBu3 in the presence of water

The Sodium Cuprate (<i>t</i>Bu₃Si)₂CuNa: Formation and X-ray Crystal Structure Analysis

(tBu3Si)2CuNa(THF)n (1; n = 2, 4) is the first structurally characterized sodium cuprate and represents a heavier homologue of the well-known lithium cuprates. Yellow crystals of (tBu3Si)2CuNa(THF)2 (1a) were obtained from heptane (space group P21/n); the ion-separated form (tBu3Si)2CuNa(THF)4 (1b) crystallized from toluene (space group R3̄)

The Sodium Siloxides (<i>t</i>Bu₃SiONa)₄ and (<i>t</i>Bu₂PhSiONa)₄: Synthesis and X-ray Crystal Structure Analysis

The sodium siloxides (tBu3SiONa)4 and (tBu2PhSiONa)4 can be synthesized almost quantitatively from the reaction of the sodium silanides tBu3SiNa and tBu2PhSiNa with N2O in tetrahydrofuran at −78 °C. (tBu3SiONa)4 and (tBu2PhSiONa)4 are the first structurally characterized sodium siloxides featuring a heterocubane framework in the solid state. X-ray quality crystals of the supersilanol, tBu3SiOH (monoclinic, C2/c), were obtained from the thermolysis of tBu3SiNaN−NNSitBu3 in the presence of water

The Sodium Siloxides (<i>t</i>Bu₃SiONa)₄ and (<i>t</i>Bu₂PhSiONa)₄: Synthesis and X-ray Crystal Structure Analysis

The sodium siloxides (tBu3SiONa)4 and (tBu2PhSiONa)4 can be synthesized almost quantitatively from the reaction of the sodium silanides tBu3SiNa and tBu2PhSiNa with N2O in tetrahydrofuran at −78 °C. (tBu3SiONa)4 and (tBu2PhSiONa)4 are the first structurally characterized sodium siloxides featuring a heterocubane framework in the solid state. X-ray quality crystals of the supersilanol, tBu3SiOH (monoclinic, C2/c), were obtained from the thermolysis of tBu3SiNaN−NNSitBu3 in the presence of water

The Sodium Siloxides (<i>t</i>Bu₃SiONa)₄ and (<i>t</i>Bu₂PhSiONa)₄: Synthesis and X-ray Crystal Structure Analysis

The sodium siloxides (tBu3SiONa)4 and (tBu2PhSiONa)4 can be synthesized almost quantitatively from the reaction of the sodium silanides tBu3SiNa and tBu2PhSiNa with N2O in tetrahydrofuran at −78 °C. (tBu3SiONa)4 and (tBu2PhSiONa)4 are the first structurally characterized sodium siloxides featuring a heterocubane framework in the solid state. X-ray quality crystals of the supersilanol, tBu3SiOH (monoclinic, C2/c), were obtained from the thermolysis of tBu3SiNaN−NNSitBu3 in the presence of water

MOESM2 of Hypo- or hyperactivity of zebrafish embryos provoked by neuroactive substances: a review on how experimental parameters impact the predictability of behavior changes

Additional file 2. Excel sheet 1—111 Literature search hits and the corresponding chemicals. Excel sheet 2—31 chemical hits after regrouping and elimination of chemicals with less than 3 entries. Excel sheet 3—Final 18 chemical hits and the experimental parameters analyzed in the main text of this study. Excel sheet 4—Summary of comparative analysis performed in this study as shown in Table 3 of the main text

MOESM1 of Hypo- or hyperactivity of zebrafish embryos provoked by neuroactive substances: a review on how experimental parameters impact the predictability of behavior changes

Additional file 1. Detailed comparison of individual substances for all 18 substances represented in Figure 3 of main text. Table S1. Sources of fish embryo lethality data used in Figure 3 of main text. Figure S1. Summary of the literature selection process in KNIME

Additional file 1: of Regional differences of outpatient physician supply as a theoretical economic and empirical generalized linear model

Diagnostics of empirical models and intercepts of the different ASHIPs. The file contains a diagnostics GP-density model, diagnostics specialist-density model, and a diagnostics ratio model. All intercepts of ASHIPs in the states of former East Germany have a negative association with the ratio of GPs to specialists. Only the ASHIP regions of the former West German states Westphalia and Saarland also show negative correlations