Clinical presentation, sexual function and quality of life as predictors of sexual satisfaction among women with urinary incontinence before a vaginal revitalization procedure

Purpose: Urinary incontinence (UI) is a common condition among women that affects quality of life, depressive symptoms and sexual function. The aim of the study was to verify whether clinical data, sexual dysfunction and quality of life may be independent predictors of life satisfaction of women with UI. Methods: The study group included 76 patients who reported to a gynaecological clinic for vaginal revitalisation due to symptoms typical of UI. The patients completed: Life Satisfaction Questionnaire (FLZ), Female Sexual Function Index (FSFI), Incontinence Quality of Life Questionnaire (I-QOL) and Beck Depression Inventory (BDI). Results: The UI patients presented a lower mean score regarding satisfaction with sex than a comparable healthy population. A high score on the FLZ-sex scale was predicted by lack of labour complications, a high score on the FLZ-health and FLZ-relationships scales, and FSFI arousal scale. Conclusions: UI appears to be linked particularly strongly to low satisfaction with sex as a dimension of life satisfaction. Memory of labour complications was associated to dissatisfaction with sex. On the other hand, no link between satisfaction with sex and episiotomy, caesarean section or natural childbirth was found. High satisfaction with sex was linked to high satisfaction with general health and relationship, as well as high arousal as a sexual function

The use of CA125, human epididymis protein 4 (HE4), risk of ovarian malignancy algorithm (ROMA), risk of malignancy index (RMI) and subjective assessment (SA) in preoperative diagnosing of ovarian tumors

Objectives: To compare utility of CA125, human epididymis protein 4 (HE4), risk of ovarian malignancy algorithm (ROMA), risk of malignancy index (RMI) and subjective assessment (SA) in preoperative diagnosis of ovarian tumors. Material and methods: Research was conducted among 456 patients qualified for surgery due to ovarian tumor. Preoperatively, CA125 and HE4 serum levels were estimated, and transvaginal ultrasound was performed. ROMA and RMI values and SA qualifications were obtained. Results were compared with pathomorphological findings. Results: Receiver Operating Characteristic (ROC)-Area Under Curve (AUC) values for CA125, HE4, ROMA, RMI and SA in preoperative diagnosis of malignant lesions were 0.819, 0.909, 0.911, 0.895 and 0.895, respectively. Combinations of biochemical and sonographic methods increased sensitivity in diagnosis of ovarian tumors. Combinations utilizing serum HE4 concentrations were most useful. Conclusions: CA125, HE4, ROMA, RMI and SA proved to be useful in preoperative diagnosis of ovarian tumors. HE4 and ROMA occurred to be the most useful. Ultrasonographic methods are considerably useful in diagnosis of ovarian tumors. RMI and SA present similar overall diagnostic value