Geology of the Cuesta Ridge Ophiolite Remnant near San Luis Obispo , California: Evidence for the Tectonic Setting and Origin of the Coast Range Ophiolite

The Cuesta Ridge ophiolite is one of the best-preserved remnants of mid-Jurassic ophiolite in California. Geologic mapping and petrologic studies show that it comprises (1) harzburgite mantle tectonite, (2) dunite-rich mantle transition zone (MTZ), (3) wehrlite and pyroxenite, (4) isotropic gabbro, (5) sheeted dike/sill complex, (6) volcanic rocks (7) late-stage dikes and flows, and (8) tuffaceous radiolarian chert. The sheeted dike/sill complex is dominated by quartz diorite, with significant modal quartz and hornblende. The volcanic section is dominated by arc tholeiite and boninitic lavas. Boninites, with high MgO, Cr, and Ni comprise 40% of the volcanic rocks. Latestage dikes and lava flows below the overlying chert, have a MORB-like affinity. These data suggest formation in a supra-subduction zone setting with three stages of arc-related magmatism before late-stage MORB magmatism. I infer formation above the east-dipping proto-Franciscan subduction zone and suggest that ophiolite formation was terminated by a ridge subduction/collision event

Guadalupe pluton–Mariposa Formation age relationships in the southern Sierran Foothills: Onset of Mesozoic subduction in northern California?

We report a new 153 ± 2 Ma SIMS U-Pb date for zircons from the hypabyssal Guadalupe pluton which crosscuts and contact metamorphoses upper crustal Mariposa slates in the southern Sierra. A ~950 m thick section of dark metashales lies below sandstones from which clastic zircons were analyzed at 152 ± 2 Ma. Assuming a compacted depositional rate of ~120 m/Myr, accumulation of Mariposa volcanogenic sediments, which overlie previously stranded Middle Jurassic and older ophiolite + chert-argillite belts in the Sierran Foothills, began no later than ~160 Ma. Correlative Oxfordian-Kimmeridgian strata of the Galice Formation occupy a similar position in the Klamath Mountains. We speculate that the Late Jurassic was a time of transition from (1) a mid-Paleozoic–Middle Jurassic interval of mainly but not exclusively strike-slip and episodic docking of oceanic terranes; (2) to transpressive plate underflow, producing calcalkaline igneous arc rocks ± outboard blueschists at ~170–150 Ma, whose erosion promoted accumulation of the Mariposa-Galice overlap strata; (3) continued transpressive underflow attending ~200 km left-lateral displacement of the Klamath salient relative to the Sierran arc at ~150–140 Ma and development of the apparent polar wander path cusps for North and South America; and (4) then nearly orthogonal mid and Late Cretaceous convergence commencing at ~125–120 Ma, during reversal in tangential motion of the Pacific plate. After ~120 Ma, nearly head-on subduction involving minor dextral transpression gave rise to voluminous continent-building juvenile and recycled magmas of the Sierran arc, providing the erosional debris to the Great Valley fore arc and Franciscan trench

Promoting Motor Cortical Plasticity with Acute Aerobic Exercise: A Role for Cerebellar Circuits

Acute aerobic exercise facilitated long-term potentiation-like plasticity in the human primary motor cortex (M1). Here, we investigated the effect of acute aerobic exercise on cerebellar circuits, and their potential contribution to altered M1 plasticity in healthy individuals (age: 24.8±4.1 years). In Experiment   1, acute aerobic exercise reduced cerebellar inhibition (CBI) (n=10, p=0.01), elicited by dual-coil paired-pulse transcranial magnetic stimulation. In Experiment   2, we evaluated the facilitatory effects of aerobic exercise on responses to paired associative stimulation, delivered with a 25 ms (PAS25) or 21 ms (PAS21) interstimulus interval (n=16 per group). Increased M1 excitability evoked by PAS25, but not PAS21, relies on trans-cerebellar sensory pathways. The magnitude of the aerobic exercise effect on PAS response was not significantly different between PAS protocols (interaction effect: p=0.30); however, planned comparisons indicated that, relative to a period of rest, acute aerobic exercise enhanced the excitatory response to PAS25 (p=0.02), but not PAS21 (p=0.30). Thus, the results of these planned comparisons indirectly provide modest evidence that modulation of cerebellar circuits may contribute to exercise-induced increases in M1 plasticity. The findings have implications for developing aerobic exercise strategies to “prime” M1 plasticity for enhanced motor skill learning in applied settings

Novel measures of cardiovascular health and its association with prevalence and progression of age-related macular degeneration: the CHARM study

<p>Abstract</p> <p>Background</p> <p>To determine if novel measures of cardiovascular health are associated with prevalence or progression of age-related macular degeneration (AMD).</p> <p>Methods</p> <p>Measures of the cardiovascular system: included intima media thickness (IMT), pulse wave velocity (PWV), systemic arterial compliance (SAC), carotid augmentation index (AI). For the prevalence study, hospital-based AMD cases and population-based age- and gender-matched controls with no signs of AMD in either eye were enrolled. For the progression component, participants with early AMD were recruited from two previous studies; cases were defined as progression in one or both eyes and controls were defined as no progression in either eye.</p> <p>Results</p> <p>160 cases and 160 controls were included in the prevalence component. The upper two quartiles of SAC, implying good cardiovascular health, were significantly associated with increased risk of AMD (OR = 2.54, 95% CL = 1.29, 4.99). High PWV was associated with increased prevalent AMD. Progression was observed in 82 (32.3%) of the 254 subjects recruited for the progression component. Higher AI (worse cardiovascular function) was protective for AMD progression (OR = 0.30, 95%CL = 0.13, 0.69). Higher aortic PWV was associated with increased risk of AMD progression; the highest risk was seen with the second lowest velocity (OR = 6.22, 95% CL = 2.35, 16.46).</p> <p>Conclusion</p> <p>The results were unexpected in that better cardiovascular health was associated with increased risk of prevalent AMD and progression. Inconsistent findings between the prevalence and progression components could be due to truly different disease etiologies or to spurious findings, as can occur with inherent biases in case control studies of prevalence. Further investigation of these non-invasive methods of characterizing the cardiovascular system should be undertaken as they may help to further elucidate the role of the cardiovascular system in the etiology of prevalent AMD and progression.</p

Identification of the optical counterparts of high-mass X-ray binaries through optical photometry and spectroscopy

We present the results of our search for optical counterparts to high-mass X-ray transient sources discovered by various X-ray missions. We obtained CCD images of the X-ray fields through BVR and Halpha filters in order to identify early-type stars in the R-Halpha versus B-V colour-colour diagram. We also obtained medium-resolution spectroscopy of the candidates in order to confirm the presence of H\alpha emission and perform spectral classification. We report on the discovery of the optical counterparts to two X-ray sources: XTE J1858+034 and IGR J01363+6610, and the follow-up observations of another two, newly identified by our group: SAX J2103.5+4545 and GRO J2058+42. For another source, IGR J00370+6122, we present the first detailed optical spectral analysis. The optical photometry and spectroscopy reveal B-type companions in all five sources; GRO J2058+42, SAX J2103.5+4545 and IGR J01363+6610 are positively identified with Be/X-ray binaries, IGR J00370+6122 with a supergiant X-ray binary, while the nature of XTE J1858+034 is uncertain. We also study the relationship between the optical and X-ray emission during quiescent states.Comment: 10 pages, to be published in A&

Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3% for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table, submitted to European Physical Journal