sj-docx-1-aop-10.1177_10600280231158929 – Supplemental material for Comparison of the Correlation Between Coagulation Indices and Rivaroxaban Concentrations

Supplemental material, sj-docx-1-aop-10.1177_10600280231158929 for Comparison of the Correlation Between Coagulation Indices and Rivaroxaban Concentrations by Tingting Wu, Shuyi Wu, Meijuan Li and Jinhua Zhang in Annals of Pharmacotherapy</p

Effects of Polyacrylonitrile/MoS₂ Composite Nanofibers on the Growth Behavior of Bone Marrow Mesenchymal Stem Cells

In recent years, molybdenum disulfide (MoS₂) as a typical class of two-dimensional (2D) materials has attracted wide attention because of its various fascinating properties. In this study, we fabricated MoS₂ composite nanofibers by electrospinning technology combined with a doping method. The as-prepared MoS₂ composite nanofibers exhibited excellent biocompatibility. In addition, the detailed investigation about the response of MoS₂ composite nanofibers on bone marrow mesenchymal stem cells (BMSCs) indicated that the obtained MoS₂ composite nanofibers could promote BMSC growth behavior, improve BMSC contact with each other, maintain cellular activity, and also provide positive promotion to regulate cellular proliferation. Moreover, the alkaline phosphatase expression significantly increased with increasing MoS₂ concentration. Compared with the excellent biocompatibility and natural extracellular-matrix-like structure, we believe that the MoS₂ composite nanofibers could provide new insight for the preparation of well-defined MoS₂ nanostructure materials and will have promising potential in biomedical applications, such as tissue engineering, photothermal therapy, etc

Strong Facet-Induced and Light-Controlled Room-Temperature Ferromagnetism in Semiconducting β‑FeSi₂ Nanocubes

Crystalline β-FeSi₂ nanocubes with two {100} facets and four {011} lateral facets synthesized by spontaneous one-step chemical vapor deposition exhibit strong room-temperature ferromagnetism with saturation magnetization of 15 emu/g. The room-temperature ferromagnetism is observed from the β-FeSi₂ nanocubes larger than 150 nm with both the {100} and {011} facets. The ferromagnetism is tentatively explained with a simplified model including both the itinerant electrons in surface states and the local moments on Fe atoms near the surfaces. The work demonstrates the transformation from a nonmagnetic semiconductor to a magnetic one by exposing specific facets and the room-temperature ferromagnetism can be manipulated under light irradiation. The semiconducting β-FeSi₂ nanocubes may have large potential in silicon-based spintronic applications

Copolymerization with Polyether Segments Improves the Mechanical Properties of Biodegradable Polyesters

To improve the properties of poly­(butylene succinate) (PBS), a series of poly­[(butylene succinate)-<i>co</i>-poly­(tetramethylene glycol)]­s (PBSTMGs) with different poly­(tetramethylene glycol) (PTMG) contents were successfully prepared by the catalyzed melt polycondensation process. The effect of introducing flexible PTMG segments on the properties was investigated, and they were compared to those of PBS. The differential scanning calorimetry results indicated that the melting temperature, crystallization temperature, and crystallinity of PBSTMG copolymers were slightly lower than those of PBS. Furthermore, these thermal parameters decreased gradually with the increase of PTMG content. Dynamic mechanical analysis showed that there was a significant decline of storage modulus (<i>E</i>′) in the overall temperature range of copolymers compared to that of PBS. The incorporation of PTMG did not modify the crystal lattice of PBS according to the wide-angle X-ray diffraction analysis. Because of copolymerization, the size of the spherulites was reduced at high PTMG contents. The soft domain in the copolymers might contribute to the enhanced tear strength of PBSTMG. The elongation at break and impact strength of PBSTMG copolymers were greatly improved as a result of the phase separation structure and lower degree of crystallinity. Especially, when the PTMG content was 10 mol %, the impact strength of the copolymer reached up to 4.5 times that of PBS. In addition, with more soft segments introduced, the biodegradability of the copolymers became much better than that of PBS

Highly Effective Multifunctional Solar Evaporator with Scaffolding Structured Carbonized Wood and Biohydrogel

A solar evaporator that utilizes solar radiation energy can be a renewable approach to deal with energy crisis and fresh water shortage. In this study, a solar evaporator was prepared by assembling composite carbonized wood of Melaleuca Leucadendron L. and biobased hydrogel. The multilayer MXene (Ti3C2Tx) was embedded in the scaffolding structure of the wood to form composite carbonized wood, where the loose and ordered scaffolding structure of the carbonized wood significantly improves the efficiency of water transportation with increased capillary force. The MXene adsorbed in the carbonized wood has high binding energy with water molecules, leading to reduction of vaporization enthalpy and contact angle. Moreover, the addition of MXene can improve the light absorbance, especially for the infrared and ultraviolet light bands. The hydrogel was fabricated by crosslinking konjac glucomannan and sodium alginate polysaccharides with Ca2+, and it has a lower thermal conductivity than water and improves the evaporation efficiency by regulating the temperature distribution and concentrating the heat on the surface of the evaporator. This solar evaporator has an evaporation rate of 3.71 kg·m–2·h–1 and an evaporation efficiency of 129.64% under 2 sun illumination and is available to generate an open-circuit voltage of 1.8 mV after a 20 min hydrovoltaic, demonstrating a high performance and versatility. Also, experiments and numerical simulation were carried out to understand the mechanism and design principles of this solar evaporators

Synergistic Effects of Conductive Three-Dimensional Nanofibrous Microenvironments and Electrical Stimulation on the Viability and Proliferation of Mesenchymal Stem Cells

In recent years, three-dimensional (3D) scaffolds have proven to be highly advantageous in mammalian cell culture and tissue engineering compared to 2D substrates. Herein, we demonstrated the fabrication of novel 3D core–shell nanofibers (3D-CSNFs) using an improved electrospinning process combined with in situ surface polymerization. The obtained 3D nanofibrous scaffold displayed excellent mechanical and electrical properties. Moreover, the cotton-like 3D structure with large internal connected pores (20–100 μm) enabled cells to easily infiltrate into the interior of the 3D scaffold with a good spatial distribution to mimic the ECM-like cell microenvironments. Stable cell–fiber composite constructs were formed in the 3D-CSNFs with relatively higher adhesion and viability compared to 2D-CSNFs. Furthermore, the human mesenchymal stem cells (hMSCs) cultured on conductive polymer coated electrically active 3D nanofibers responded with a healthy morphology and anchorage on the fibers with relatively higher viability and proliferation under electrical stimulation (ES). This study demonstrates the successful fabrication of 3D-CSNFs and the constructive interaction of the 3D microenvironment and subsequent electrical stimulations on hMSCs, thereby holding promising potential in tissue engineering and regenerative therapies aided by electro-stimulation-based differentiation strategies

Phase-Engineering-Induced Generation and Control of Highly Anisotropic and Robust Excitons in Few-Layer ReS₂

The anisotropic exciton behavior in two-dimensional materials induced by spin–orbit coupling or anisotropic spatial confinement has been exploited in imaging applications. Herein, we propose a new strategy to generate high-energy and robust anisotropic excitons in few-layer ReS₂ nanosheets by phase engineering. This approach overcomes the limitation imposed by the layer thickness, enabling production of visible polarized photoluminescence at room temperature. Ultrasonic chemical exfoliation is implemented to introduce the metallic T phase of ReS₂ into the few-layer semiconducting Td nanosheets. In this configuration, light excitation can readily produce “hot” electrons to tunnel to the Td phase via the metal–​semiconductor interface to enhance the overlap between the wave functions and screened Coulomb interactions. Owing to the strong electron–hole interaction, significant increase in the optical band gap is observed. Highly anisotropic and tightly bound excitons with visible light emission (1.5–2.25 eV) are produced and can be controlled by tailoring the T phase concentration. This novel strategy allows manipulation of polarized optical information and has great potential in optoelectronic devices