130 research outputs found

    Recent Studies upon Peristalsis Recovery from Postoperative Paralytic Ileus(TOPIC)

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    Top view video corresponding to the case of 90° Originally published in Optics Express on 13 June 2016 (oe-24-12-13258

    Biosynthesis of 7,8-dihydroxyflavone glycosides via OcUGT1-catalyzed glycosylation and transglycosylation

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    <p>Herein, a flavonoid glycosyltransferase (GT) OcUGT1 was determined to be able to attack C-8 position of 7,8-dihydroxyflavone (7,8-DHF) via both glycosylation and transglycosylation reactions. OcUGT1-catalyzed glycosylation of 7,8-DHF resulted in the formation of two monoglycosides 7-<i>O</i>-β-D-glucosyl-8-hydroxyflavone (<b>1a</b>), 7-hydroxy-8-<i>O</i>-β-D-glucosylflavone (<b>1b</b>), as well as one diglycoside 7,8-di-<i>O</i>-β-D-glucosylflavone (<b>1c</b>). Under the action of OcUGT1, inter-molecular trans-glycosylations from aryl β-glycosides to 7,8-DHF to form monoglycosides <b>1a</b> and <b>1b</b> were observable.</p

    Fuzzy logic-based arbitration for shared control in continuous human-robot collaboration

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    In human-robot collaboration (HRC) tasks, the role of the robot should be naturally and smoothly transitioned between the leader and the follower to guarantee task performance. To realize this, the arbitration of the shared control between the human and the robot needs to be properly designed to assign a degree of leadership to the robot. In this paper, we propose a fuzzy logic-based arbitration rule with the help of Kalman filter (KF). Based on this rule, the arbitration can be continuously regulated between zero and one according to the interaction force and the velocity of the human-robot collaboration system with human intention taken into account. Besides, the distance between the system and the obstacle and more generally the environment is also served as a fuzzy input, so that the possible interaction with the environment, e.g., obstacle avoidance, can be considered to ensure system safety. Since our proposed arbitration rule is based on a fuzzy logic, it endows the robot with the capability of continuous reasoning without an explicit form. The effectiveness of the proposed algorithm is evaluated by experiments.</p

    Comparison of ΔVAS in different time intervals.

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    <p>* Statistically significant between less than 6 months group and 6–12 months group (LSD-t test).</p><p>* Statistically significant between less than 6 months group and more than 12 months group (LSD-t test).</p><p>Comparison of ΔVAS in different time intervals.</p

    Comparison of the general information between the first and second surgery in staged TKA.

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    <p>Comparison of the general information between the first and second surgery in staged TKA.</p

    DataSheet_1_Causal association between celiac disease and inflammatory bowel disease: A two-sample bidirectional Mendelian randomization study.doc

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    BackgroundAn epidemiological link between celiac disease (CeD) and inflammatory bowel disease (IBD) has been well established recently. In this study, Mendelian randomization (MR) analysis was performed employing pooled data of publicly available genome-wide association studies (GWAS) to determine the causal relationship between CeD and IBD, encompassing ulcerative colitis (UC) and Crohn’s disease (CD).MethodsDataset of CeD was acquired from GWAS for 12,041 cases and 12,228 controls. A GWAS of more than 86,000 patients and controls was used to identify genetic variations underlying IBD. MR analyses were performed with an inverse-variance-weighted approach, an MR-Egger regression, a weighted-mode approach, a weighted-median method, and sensitivity analyses of MR pleiotropy residual sum and outlie (MR-PRESSO).ResultsMR demonstrated that genetic predisposition to CeD was linked to a augmented risk of IBD (OR: 1.1408; 95% CI: 1.0614-1.2261; P = 0.0003). In the analysis of the two IBD subtypes, genetic predisposition to CeD was also linked to increased risks of UC (OR: 1.1646; 95% CI: 1.0614-1.2779; P = 0.0012) and CD (OR: 1.1865; 95% CI: 1.0948-1.2859; P = 3.07E-05). Reverse MR analysis results revealed that genetic susceptibility to IBD and CD was correlated with an augmented risk of CeD. However, there was no genetic correlation between UC and CeD. All of the above results were validated with other GWAS databases.ConclusionThere is a bidirectional causal relationship of CeD with IBD and CD. However, UC only augments the risk of developing CeD.</p
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