Shift-encoded optically multiplexed imaging

In a multiplexed image, multiple fields-of-view (FoVs) are superimposed onto a common focal plane. The attendant gain in sensor FoV provides a new degree of freedom in the design of an imaging system, allowing for performance tradeoffs not available in traditional optical designs. We explore design choices relating to a shift-encoded optically multiplexed imaging system and discuss their performance implications. Unlike in a traditional imaging system, a single multiplexed image has a fundamental ambiguity regarding the location of objects in the image. We present a system that can shift each FoV independently to break this ambiguity and compare it to other potential disambiguation techniques. We then discuss the optical, mechanical, and encoding design choices of a shift-encoding midwave infrared imaging system that multiplexes six 15×15  deg FoVs onto a single one megapixel focal plane. Using this sensor, we demonstrate a computationally demultiplexed wide FoV video.United States. Air Force Office of Scientific Research (FA8721-05-C-0002

Street developments : case of Ahmedabad, India

Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning; and, (M.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1982.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ROTCH.Bibliography: p. 69-70.by Vinay Shah.M.C.P

The Test Your Memory cognitive screening tool: sociodemographic and cardiometabolic risk correlates in a population-based study of older British men.

OBJECTIVE: This study aimed to examine the association of Test Your Memory (TYM)-defined cognitive impairment groups with known sociodemographic and cardiometabolic correlates of cognitive impairment in a population-based study of older adults. METHODS: Participants were members of the British Regional Heart Study, a cohort across 24 British towns initiated in 1978-1980. Data stemmed from 1570 British men examined in 2010-2012, aged 71-92 years. Sociodemographic and cardiometabolic factors were compared between participants defined as having TYM scores in the normal cognitive ageing, mild cognitive impairment (MCI) and severe cognitive impairment (SCI) groups, defined as ≥46 (45 if ≥80 years of age), ≥33 and <33, respectively. RESULTS: Among 1570 men, 636 (41%) were classified in the MCI and 133 (8%) in the SCI groups. Compared with participants in the normal cognitive ageing category, individuals with SCI were characterized primarily by lower socio-economic position (odds ratio (OR) = 6.15, 95% confidence interval (CI) 4.00-9.46), slower average walking speed (OR = 3.36, 95% CI 2.21-5.10), mobility problems (OR = 4.61, 95% CI 3.04-6.97), poorer self-reported overall health (OR = 2.63, 95% CI 1.79-3.87), obesity (OR = 2.59, 95% CI 1.72-3.91) and impaired lung function (OR = 2.25, 95% CI 1.47-3.45). A similar albeit slightly weaker pattern was observed for participants with MCI. CONCLUSION: Sociodemographic and lifestyle factors as well as adiposity measures, lung function and poor overall health are associated with cognitive impairments in late life. The correlates of cognitive abilities in the MCI and SCI groups, as defined by the TYM, resemble the risk profile for MCI and Alzheimer's disease outlined in current epidemiological models. © 2016 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons, Ltd

Development of a syntactic-based sandwich composite for blast- Resistance modular buildings

Since the inception of the blast resistant modular (BRM) construction industry in the early 1990s, the favored material of construction has been steel. Steel is well suited for this application as the mechanical response is favorable for mitigating the overpressure from a blast event thus protecting the inhabitant and equipment inside the structure. The main drawbacks to using steel-based construction are the high weight, high maintenance cost because of corrosion and the large amounts of welding needed to manufacture such a structure. Each of these drawbacks has a direct and significant impact on increasing the life cycle cost. Incorporating composite materials can address each of these drawbacks. Drawing analogies from the evolution of commercial aircraft, we use similar light-weighting strategies to replace and reduce part-count of metal components with multifunctional, lightweight composite-based solutions. We focus on polymer-based sandwich composites with the core made from syntactic foam. We fully characterize the mechanical and physical properties of the syntactic core and sandwich panel. In addition, we present the response of a panel and the BRM structure when exposed to an eight psi, 200 milliseconds overpressure event, simulating and blast event. Finally, we will conclude with a cost-benefit analysis showing that, as seen in the aircraft industry, replacing metals with composite materials have higher initial raw material costs but will reduce the overall lifecycle costs

Design and control of a nonlinearly compliant robotic finger

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1997.Includes bibliographical references (p. 65-67).by Vinay Kishore Shah.M.S

Asymptomatic COVID-19-Associated Acquired Hemophilia A and Disseminated Intravascular Coagulation From a Bypassing Agent

Acquired hemophilia A (AHA) is a clotting disorder characterized by the presence of neutralizing antibodies that inhibit factor VIII, resulting in increased bleeding risk. Known etiologies include malignancy, autoimmune conditions, graft-vs-host disease, and more recently coronavirus disease 2019 (COVID-19) infection. In this case report, we describe an 86-year-old female who was found to have AHA incidentally during preoperative workup for meningioma resection. She was subsequently found to have COVID-19 infection which was the likely cause of her development of AHA. She was treated with factor eight inhibitor bypassing agent (FEIBA) and recombinant factor VII (rVII) for a small hematoma on her right arm along with prednisone and cyclophosphamide. She then developed disseminated intravascular coagulation (DIC) initially secondary to FEIBA and subsequently rFVII. DIC resolved after these factor concentrates were withheld. The aim of this case report was to emphasize the importance of monitoring partial thromboplastin time (PTT) in patients with COVID-19 and proceeding with AHA workup if indicated. It is also imperative to know and understand the potentially life-threatening, albeit rare, adverse effects of DIC associated with the administration of factor concentrates, especially in the elderly population and withholding these factor concentrates once DIC is suspected

TO ACCESS THE EFFECT OF PIPALLI CHOORNA AND SHATAVARI CHOORNA IN STANYAKSHAYA

Aim: To access the effect of Pipalli and Shatavari choorna with Shukhoshna godugdha in Stanyakshaya. Objective: Study of literature regarding Stanyakshaya and Pippli choorna. Observation on the effect of Pippali choorna with Godugdha on lactating mother and observe if any adverse effect.Method: Study Group: 60 patients were observed &amp; treated, Study divided in two groups 30 patients in each group. In Group A (Trial Group) 30 patients are randomly selected in which Stanyakshaya will be treated with Pipplichoorna, 500 mg twice daily after meals with Sukhoshana Godugdha. In Group B (Control Group) 30 patients are Group of randomly selected in which Stanya Jananan drug Shatavarimool choorna 2 gm twice daily with Godugdha after meal. A follow up was done on each patient after every 7 days. Initially all the signs and symptoms were noted thoroughly. Change in signs and symptoms in each follow up were observed and noted in case paper. Follow up was done for 3 weeks during treatment and for 2 weeks after treatment. The total duration of treatment was 21 days.Results: Comparing all the symptoms before and after treatment had positive results of  treatment given to group B (Shatavari Choorna) showed slightly better results over treatment given to group A (Pippali choorna). The Statistical Analysis reveals that Shatavari Choorna with Shukhoshna godugdha in the management of Stanyakshaya is more effective than Pippalichoorna with Shukhoshna godugdha. Conclusion: Treatment given to group B (Shatavari Choorna) showed better results over treatment given to group A (Pippali choorna), we can conclude that treatment Shatavari Choorna given to group B is better for this disease Stanyakshaya

Biologic and Checkpoint Inhibitor-Induced Liver Injury: A Systematic Literature Review

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked DownloadBiologics are among the most commonly prescribed medications for several chronic inflammatory diseases. Tumor necrosis factor alpha inhibitors, more so than other agents, have been observed to cause drug-induced liver injury. Additionally, because the approval and popularity of checkpoint inhibitors have grown, similar patterns of liver injury have been documented, with a majority of cases describing immune-mediated hepatitis. Although the exact mechanism of injury is unknown, various host and medication characteristics play a role in the outcome of the molecular cascade invoked by biologics. Prognosis is usually favorable with cessation of the offending agent, but cases of acute liver failure requiring liver transplantation have also been observed. Therefore, algorithms have been created to assist clinicians in treating drug-induced autoimmune hepatitis, mostly with corticosteroids. Additionally, case reports have documented successfully rechallenging patients with a different biologic without recurrence of liver injury, but data are limited. Further investigation is warranted regarding the potential for cross-reactivity and mechanism of injury to develop guidelines to aid clinicians in further management of these patients

Krill’s Disease: A Newer Management Option

Purpose: To report a case of a young female who presented with scotoma in the right eye for few days. Case Report: Krill’s disease or acute retinal pigment epithelitis (ARPE) is a self-limiting retinal disease with no specific treatment. Typical clinical and imaging features helped us to diagnose her with ARPE. Intravenous methylprednisolone (IVMP), which gives a rapid anti-inflammatory response, was advised. An SD-OCT scan post-injection showed a reduction in hyperreflectivity and height of lesion at day 3 and near total resolution by day 5. Conclusion: This case suggests rapid resolution of ARPE with the use of IVM