Conjunction analysis of <i>desirable > undesirable</i> (displayed at the threshold <i>P_uncorrected <</i>0.001).

<p>Peak activity was located in superior orbito-frontal cortex (−4, 46, −6 SVC) and is shown in sagittal section (A). Parameter estimates for the three stimulus categories and for the three desirability classifications (B). A proximal voxel (−6, 46, −4, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003027#pone-0003027-g006" target="_blank">Fig 6A</a>) exhibits a linear relationship with desirability. Figure (C) shows the overlap in areas of cortex activated by each stimulus category (in red, green, and yellow) on sections through a template brain at −4, 46, −6.</p

Conjunction analysis of <i>desirable > indifferent</i> (displayed at the threshold <i>P_uncorrected <</i>0.001).

<p>Peak activity was located in the mid-cingulate cortex (MC above) (0, 2, 36, SVC). Another activation was in anterior cingulate cortex (AC above) (0, 34, 4 SVC). Both are shown in sagittal section (A). Parameter estimates for the three stimulus categories and for the three desirability classifications for MC (B) and for AC (C). The peak activity voxel in MC at 0, 2, 36 falls within the cluster of active voxels shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003027#pone-0003027-g006" target="_blank">Fig 6B</a> which exhibit a quadratic relationship with desirability.</p

Locations shown in sagittal section and parameter estimates showing modulation by desirability rating (A) linear (1^st order) relationship in SOFC at −6, 46, −4, (B) quadratic (2^nd order) relationship in MC at −2, 2, 36.

<p>Locations shown in sagittal section and parameter estimates showing modulation by desirability rating (A) linear (1^st order) relationship in SOFC at −6, 46, −4, (B) quadratic (2^nd order) relationship in MC at −2, 2, 36.</p

Areas in which brain activity for three stimulus categories showed parametric modulation by desirability rating (<i>P_uncorrected <</i>0.001); (A) linear (1^st order) relationship, (B) quadratic (2^nd order) relationship.

<p>Activations are shown superimposed on successive sagittal sections (x = −4, 0, 4).</p

Behavioral data collected in the fMRI study.

<p>(A) Distribution of desirability classifications by stimulus category, averaged over all subjects. Range shows minimum and maximum percentages among subjects. (B) Averaged response times in milliseconds by stimulus category and response classification. S.D. shows sample standard deviation. Range shows minimum and maximum response times, which were averaged within subject, among subjects. Each stimulus category includes 72 trials (a total of 216 trials for a subject).</p

Examples of stimuli for (A) ‘events’ (upper, cycling; middle, fireworks; lower, swimming) (B) ‘persons’ (upper, politician; middle, anonymous male; lower, anonymous female), and (C) ‘objects’ (upper, cake; middle, mobile phone; lower, car).

<p>Only events stimuli had subtitles.</p

Statistical parametric maps rendered onto a template structural brain, showing category-specific activity as assessed by conjunction analysis, in the comparisons of (A) <i>events > non-events</i>, (B) <i>persons > non-persons</i>, and (C) <i>objects > non-objects</i>.

<p>Statistical parametric maps rendered onto a template structural brain, showing category-specific activity as assessed by conjunction analysis, in the comparisons of (A) <i>events > non-events</i>, (B) <i>persons > non-persons</i>, and (C) <i>objects > non-objects</i>.</p