Additional file 1: of Use of existing systematic reviews for evidence assessments in infectious disease prevention: a comparative case study

Case study A: flow chart for the systematic literature search and study selection. (DOCX 87 kb

Monthly outbreaks – Mandatory outbreak reporting in Germany, 1 November 2011 to 31 October 2012.

<p>Monthly outbreaks – Mandatory outbreak reporting in Germany, 1 November 2011 to 31 October 2012.</p

Additional file 2: of The rise in vancomycin-resistant Enterococcus faecium in Germany: data from the German Antimicrobial Resistance Surveillance (ARS)

Figure S1. Sensitivity analyses of time trend of vancomycin-resistant E. faecium. (DOCX 91 kb

Number of outbreaks, number of all cases, colonisations, symptomatic infections and fatalities in HAI-outbreaks due to multidrug resistant organisms, Germany, 1 November 2011 to 31 October 2012.

<p>Note: Numbers of colonised, symptomatic infected and fatalities may not add up to number of all cases (see discussion). Percentages may not add up to 100% due to rounding. MRSA: Methicillin-resistant <i>Staphylococcus aureus.</i></p

Additional file 1: of The rise in vancomycin-resistant Enterococcus faecium in Germany: data from the German Antimicrobial Resistance Surveillance (ARS)

Table S1. Ratio between the total numbers of E. faecium and E. faecalis isolates in the ARS database from continuously and non-continuously participating hospitals. (DOCX 16 kb

Number of outbreaks by reporting hospital ward, Germany; 1 November 2011 to 31 October 2012.

<p>Note: Percentages may not add up to 100% due to rounding. Multidrug resistant organisms (MDROs).</p

Number of received notifications and their relation to outbreaks matching the case definition – Mandatory outbreak reporting in Germany, 1 November 2011 to 31 October 2012.

<p>Number of received notifications and their relation to outbreaks matching the case definition – Mandatory outbreak reporting in Germany, 1 November 2011 to 31 October 2012.</p

Pathogens identified in reported HAI-outbreaks (n = 578), Germany, 1 November 2011 to 31 October 2012.

<p>Median and range as min. and max. within outbreaks. Note: Numbers of colonised, symptomatic infected and fatalities may not add up to number of all cases (see discussion). Percentages may not add up to total 100% due to rounding.</p

Additional file 3: of The rise in vancomycin-resistant Enterococcus faecium in Germany: data from the German Antimicrobial Resistance Surveillance (ARS)

Table S2. Multivariable regression analysis assessing the interaction between region and year of sampling. (DOCX 18 kb

Number of outbreaks by healthcare setting and reporting healthcare facility, Germany, 1 November 2011 to 31 October 2012.

<p>Note: Percentages may not add up to 100% due to rounding. Multidrug resistant organisms (MDROs).</p