Dynamic Regimes in Films with a Periodic Array of Antidots

We have studied the dynamic response of Pb thin films with a square array of antidots by means of ac susceptibility chi(T,H) measurements. At low enough ac drive amplitudes h, vortices moving inside the pinning potential give rise to a frequency- and h-independent response together with a scarce dissipation. For higher amplitudes, the average distance travelled by vortices surpasses the pinning range and a critical state develops. We found that the boundary h*(H,T) between these regimes smoothly decreases as T increases whereas a step-like behavior is observed as a function of field. We demonstrate that these steps in h*(H) arise from sharp changes in the pinning strength corresponding to different vortex configurations. For a wide set of data at several fields and temperatures in the critical state regime, we show that the scaling laws based on the simple Bean model are satisfied.Comment: 7 pages, 5 figure

Flux pinning properties of superconductors with an array of blind holes

We performed ac-susceptibility measurements to explore the vortex dynamics and the flux pinning properties of superconducting Pb films with an array of micro-holes (antidots) and non-fully perforated holes (blind holes). A lower ac-shielding together with a smaller extension of the linear regime for the lattice of blind holes indicates that these centers provide a weaker pinning potential than antidots. Moreover, we found that the maximum number of flux quanta trapped by a pinning site, i.e. the saturation number ns, is lower for the blind hole array.Comment: 6 figures, 6 page

Dendritic flux penetration in Pb films with a periodic array of antidots

We explore the flux-jump regime in type-II Pb thin films with a periodic array of antidots by means of magneto-optical measurements. A direct visualization of the magnetic flux distribution allows to identify a rich morphology of flux penetration patterns. We determine the phase boundary $H^*(T)$ between dendritic penetration at low temperatures and a smooth flux invasion at high temperatures and fields. For the whole range of fields and temperatures studied, guided vortex motion along the principal axes of the square pinning array is clearly observed. In particular, the branching process of the dendrite expansion is fully governed by the underlying pinning topology. A comparative study between macroscopic techniques and direct local visualization shed light onto the puzzling $T-$ and $H-$independent magnetic response observed at low temperatures and fields. Finally, we find that the distribution of avalanche sizes at low temperatures can be described by a power law with exponent $\tau \sim 0.9(1)$

Field-dependent Vortex Pinning Strength in a Periodic Array of Antidots

We explore the dynamic response of vortex lines in a Pb thin film with a periodic array of antidots by means of ac-susceptibility measurements. For low drive field amplitudes, within the Campbell regime, vortex motion is of intra-valley type and the penetration depth is related to the curvature of the pinning potential well, $\alpha$. For dc-fields below the first matching field $H_1$, $\alpha$ reaches its highest value associated with a Mott Insulator-like phase where vortex lines are strongly localized at the pinning sites. For $H_1<H_{dc}<H_2$, the response is mainly due to the interstitial vortices and $\alpha$ drops to smaller values as expected for this metallic-like regime. Strikingly, for $H_2<H_{dc}<H_3$, we observe that $\alpha$ reduces further down. However, for $H_3<H_{dc}<H_4$, a reentrance in the pinning strength is observed, due to a specific configuration of the flux line lattice which strongly restricts the mobility of vortices. We present a possible explanation for the measured $\alpha(H_{dc})$ dependence based on the different flux line lattice configurations.Comment: 5 pages, to be published in Phys. Rev.

Distant non-obvious mutations influence the activity of a hyperthermophilic Pyrococcus furiosus phosphoglucose isomerase

The cupin-type phosphoglucose isomerase (PfPGI) from the hyperthermophilic archaeon Pyrococcus furiosus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. We investigated PfPGI using protein-engineering bioinformatics tools to select functionally-important residues based on correlated mutation analyses. A pair of amino acids in the periphery of PfPGI was found to be the dominant co-evolving mutation. The position of these selected residues was found to be non-obvious to conventional protein engineering methods. We designed a small smart library of variants by substituting the co-evolved pair and screened their biochemical activity, which revealed their functional relevance. Four mutants were further selected from the library for purification, measurement of their specific activity, crystal structure determination, and metal cofactor coordination analysis. Though the mutant structures and metal cofactor coordination were strikingly similar, variations in their activity correlated with their fine-tuned dynamics and solvent access regulation. Alternative, small smart libraries for enzyme optimization are suggested by our approach, which is able to identify non-obvious yet beneficial mutations

Occurrence of L-iduronic acid and putative D-glucuronyl C5-epimerases in prokaryotes

Glycosaminoglycans (GAGs) are polysaccharides that are typically present in a wide diversity of animal tissue. Most common GAGs are well-characterized and pharmaceutical applications exist for many of these compounds, e.g. heparin and hyaluronan. In addition, also bacterial glycosaminoglycan-like structures exist. Some of these bacterial GAGs have been characterized, but until now no bacterial GAG has been found that possesses the modifications that are characteristic for many of the animal GAGs such as sulfation and C5-epimerization. Nevertheless, the latter conversion may also occur in bacterial and archaeal GAGs, as some prokaryotic polysaccharides have been demonstrated to contain L-iduronic acid. However, experimental evidence for the enzymatic synthesis of L-iduronic acid in prokaryotes is as yet lacking. We therefore performed an in silico screen for D-glucuronyl C5-epimerases in prokaryotes. Multiple candidate C5-epimerases were found, suggesting that many more microorganisms are likely to exist possessing an L-iduronic acid residue as constituent of their cell wall polysaccharides

Guided vortex motion in superconductors with a square antidot lattice

We have measured the in-plane anisotropy of the vortex mobility in a thin Pb film with a square array of antidots. The Lorentz force, acting on the vortices, was rotated by adding two perpendicular currents and keeping the amplitude of the net current constant. One set of voltage probes was used to detect the vortex motion. We show that the pinning landscape provided by the square antidot lattice influences the vortex motion in two different ways. First, the modulus of the vortex velocity becomes angular dependent with a lower mobility along the diagonals of the pinning array. Second, the vortex displacement is preferentially parallel to the principal axes of the underlying pinning lattice, giving rise to a misalignment between the vortex velocity and the applied Lorentz force. We show that this anisotropic vortex motion is temperature dependent and progressively fades out when approaching the normal state.Comment: 5 pages, 4 figure

Ac response of Pb thin films with a periodic pinning potential

We have studied the dynamic response of Pb thin films with a square array of antidots by means of ac susceptibility chi(T, H) measurements. For low amplitudes h of the ac excitation, the field dependence of the ac susceptibility exhibits a series of distinctive features associated with the presence of different dynamic regimes. For fields below a certain characteristic field H-s, vortices strongly pinned by the antidots perform an oscillatory movement inside the pinning potential induced by the external ac drive. For fields between H-s and H-p, interstitial vortices, performing an intra-valley motion in the weak potential wells produced by the repulsive interaction of their pinned neighbors, dominate the ac response. For H-p < H < H-t, the interstitial vortices are driven out of their pinning sites while vortices in the antidots remain trapped. For higher fields all vortices are set in motion and a critical state develops. We show that the characteristic h-independent field H-s allows one to clearly identify the maximum number of flux quanta per hole. Unlike H-s, the fields H-p and H-t, signaling the onset of motion of interstitial vortices and vortices trapped by the antidots, respectively, strongly depend on h. (C) 2004 Elsevier B.V. All rights reserved