Rapid Curing System of a Cyanate Ester Resin/Epoxy Resin with a Thermal Latent Polymeric Hardener Based on a Phenol–Amine Salt

We studied the thermal behavior and curing process of a cyanate ester resin (Cy)/epoxy resin (EP)/thermal latent polymeric hardener system based on a phenol–amine salt (PA-hardener) and the resulting cross-linked structure. Additionally, the physical properties of the cured product were evaluated. As a result, the curing system of Cy/EP with the PA-hardener was found to have unique thermal behavior, and an adhesion process was conducted in which the functionality and reactivity of the cyanate ester resin were utilized. The system cured rapidly at approximately 80 °C and could be completely cured at 120 °C in 1 h because the PA-hardener dissolved in the resins at an elevated temperature to give free amines, which could readily initiate the polymerization of cyanate ester resins and epoxy resins. The glass-transition temperature (Tg) of the cured products increased with increasing a triazine-rich cross-linked structure derived from the cyclotrimerization of the cyanate ester resin as the curing proceeded at a relatively low temperature. The Cy/EP/PA-hardener system was found to have a rapid curing process and excellent adhesiveness, and it afforded a cured product with heat stability

DNA Separation in Nanowall Array Chips

A nanowall array structure was fabricated on a quartz chip as a separation matrix of DNA fragments, and a 30 s separation was realized for a mixture of DNA fragments (48.5 and 1 kbp fragments) by applying the electric voltage. A longer DNA fragment migrates faster than a shorter one in a nanowall array chip, and it is completely different from the separation of DNA based on gel electrophoresis, nanopillar chips, and nanoparticle array chips. Although the result is similar to DNA separation by entropic trapping, it could not be fully explained by entropic trapping phenomena. Direct observation of single-DNA molecular dynamics inside a nanowall array structure indicates that both confined elongation and relaxation recoiling of a DNA molecule occur, and an elongated DNA molecule migrates faster than a recoiled DNA molecule. Numerical fitting of DNA molecular dynamics reveals that the balance between times for the transverse of a DNA molecule in the nanowall array chip and the relaxation-recoiling of a DNA molecule governs the separation of DNA

DNA Separation in Nanowall Array Chips

A nanowall array structure was fabricated on a quartz chip as a separation matrix of DNA fragments, and a 30 s separation was realized for a mixture of DNA fragments (48.5 and 1 kbp fragments) by applying the electric voltage. A longer DNA fragment migrates faster than a shorter one in a nanowall array chip, and it is completely different from the separation of DNA based on gel electrophoresis, nanopillar chips, and nanoparticle array chips. Although the result is similar to DNA separation by entropic trapping, it could not be fully explained by entropic trapping phenomena. Direct observation of single-DNA molecular dynamics inside a nanowall array structure indicates that both confined elongation and relaxation recoiling of a DNA molecule occur, and an elongated DNA molecule migrates faster than a recoiled DNA molecule. Numerical fitting of DNA molecular dynamics reveals that the balance between times for the transverse of a DNA molecule in the nanowall array chip and the relaxation-recoiling of a DNA molecule governs the separation of DNA

Arrangement of a Nanostructure Array To Control Equilibrium and Nonequilibrium Transports of Macromolecules

Exploiting the nonequilibrium transport of macromolecules makes it possible to increase the separation speed without any loss of separation resolution. Here we report the arrangement of a nanostructure array in microchannels to control equilibrium and nonequilibrium transports of macromolecules. The direct observation and separation of macromolecules in the nanopillar array reported here are the first to reveal the nonequilibrium transport, which has a potential to overcome the intrinsic trade-off between the separation speed and resolution

sj-pptx-2-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Supplemental material, sj-pptx-2-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal</p

sj-pptx-3-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Supplemental material, sj-pptx-3-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal</p

sj-pptx-1-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Supplemental material, sj-pptx-1-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal</p

sj-pptx-5-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Supplemental material, sj-pptx-5-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal</p

sj-docx-14-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Supplemental material, sj-docx-14-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal</p

sj-docx-7-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Supplemental material, sj-docx-7-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal</p