55 research outputs found

    Prognostic and predictive value of the 21 gene recurrence sore assay in breast cancer : preliminary report

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    Por├│wnanie wynik├│w testu Oncotype DX z danymi klinicznymi dotycz─ůcymi 2 chorych na raka piersi, z grupy tzw. ┼Ťredniego ryzyka nawrotu, wskazuje, ┼╝e test ten mo┼╝e mie─ç istotne warto┼Ťci prognostyczne i predykcyjne. Szczeg├│lnie warto┼Ťciowa jest wskaz├│wka co do ewentualnej uzupe┼éniaj─ůcej chemioterapii. W naszych warunkach przeszkod─ů dla stosowania testu jest jego stosunkowo wysoka cena, tj. oko┼éo 10 573 PLN/test. Z tego powodu wskazane by┼éoby opracowanie podobnego molekularnego testu rokowniczego przez polskie o┼Ťrodki naukowe.A comparison of the results of the Oncotype DX test with the clinical data of 2 patients with node-negative estrogen receptor positive early breast cancer has shown that 21 gene recurrence score assay has both a prognostic and a predictive value, especially regarding adjuvant chemotherapy

    Fulminant heart failure due to giant cell myocarditis affecting the left ventricle

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    A 56-year-old woman, previously healthy, was hospitalized after an episode of ventricular tachycardia in the course of infection. In view of the fulminant course of heart failure the patient was connected to an extracorporeal membrane oxygenation (ECMO) system. After 3 weeks of treatment with ECMO the patient received a heart transplant. A histopathological examination of the tissues of the explanted heart revealed giant cell myocarditis. The patient was treated with immunosuppression based on induction therapy followed by a standard regimen with steroids. Currently, the patient remains in good general condition with an left ventricular ejection fraction of 60%
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