5,123 research outputs found
Lectures in Applied Mathematics. Volume VI - Space Mathematics, Part 2
Applied mathematics in celestial mechanics - theory of librational motions, earth shape, and satellite orbit calculation
Lectures in Applied Mathematics. Volume 7 - Space Mathematics, Part 3
Fluid mechanic and radiation pressure effects on satellite orbits and orbital decay, and space rendezvous maneuvers - mathematics conferenc
Cloning, sequencing, and characterization of the hexahydro-1,3,5-trinitro-1,3,5-triazine degradation gene cluster from Rhodococcus rhodochrous
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a high explosive which presents an environmental hazard as a major land and groundwater contaminant. Rhodococcus rhodochrous strain 11Y was isolated from explosive contaminated land and is capable of degrading RDX when provided as the sole source of nitrogen for growth. Products of RDX degradation in resting-cell incubations were analyzed and found to include nitrite, formaldehyde, and formate. No ammonium was excreted into the medium, and no dead-end metabolites were observed. The gene responsible for the degradation of RDX in strain 11Y is a constitutively expressed cytochrome P450-like gene, xpLA, which is found in a gene cluster with an adrenodoxin reductase homologue, xplB. The cytochrome P450 also has a flavodoxin domain at the N terminus. This study is the first to present a gene which has been identified as being responsible for RDX biodegradation. The mechanism of action of XplA on RDX is thought to involve initial denitration followed by spontaneous ring cleavage and mineralization
There are no multiply-perfect Fibonacci numbers
Here, we show that no Fibonacci number (larger than 1) divides the sum of its divisors
Potential cellular and regenerative approaches for the treatment of Parkinson’s disease
Parkinson’s disease is most commonly treated with a range of pharmacotherapeutics, with the more recent introduction of surgical techniques including deep-brain stimulation. These have limited capabilities to improve symptoms of the disease in more advanced stages, thus new therapeutic strategies including the use of viral vectors and stem cells are in development. Providing a continuous supply of dopamine to the striatum in an attempt to improve the treatment of motor symptoms using enzymes in the dopamine synthesis and machinery is one approach. Alternatively, there are tools which may serve to both protect and encourage outgrowth of surviving neurons using growth factors or to directly replace lost innervation by transplantation of primary tissue or stem cell-derived dopaminergic neurons. We summarize some of the potential therapeutic approaches and also consider the recent EU directives on practical aspects of handling viral vectors, cells and tissues, and in the running of clinical trials in Europe which impact on their development
Quantitative Chevalley-Weil theorem for curves
The classical Chevalley-Weil theorem asserts that for an \'etale covering of
projective varieties over a number field K, the discriminant of the field of
definition of the fiber over a K-rational point is uniformly bounded. We obtain
a fully explicit version of this theorem in dimension 1.Comment: version 4: minor inaccuracies in Lemma 3.4 and Proposition 5.2
correcte
Fredkin Gates for Finite-valued Reversible and Conservative Logics
The basic principles and results of Conservative Logic introduced by Fredkin
and Toffoli on the basis of a seminal paper of Landauer are extended to
d-valued logics, with a special attention to three-valued logics. Different
approaches to d-valued logics are examined in order to determine some possible
universal sets of logic primitives. In particular, we consider the typical
connectives of Lukasiewicz and Godel logics, as well as Chang's MV-algebras. As
a result, some possible three-valued and d-valued universal gates are described
which realize a functionally complete set of fundamental connectives.Comment: 57 pages, 10 figures, 16 tables, 2 diagram
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