Nowa Konstytucja Państwa Litewskiego

Digitalizacja i deponowanie archiwalnych zeszytów RPEiS sfinansowane przez MNiSW w ramach realizacji umowy nr 541/P-DUN/201

Population genetic dataset Anopheles sundaicus Mpi long alignment

DNA alignment of a fragment of Mpi (mannose phosphatase isomerase) gene from Anopheles sundaicus s.l. used for ecological study. Individual haplotypes are submitted to GenBank Popset number 261599516 and details for each specimen are given in publication Supplementary table S1

CO1_MSN

Minimum spanning network created using Arlequin

Arlequin input file of the CO1 dataset.

Arlequin input file of the CO1 dataset. Haplotypes for all individual reported separately

Arlequin input file of the Mpi dataset

Arlequin input file of the Mpi dataset. Haplotypes for all individual reported separately

Arl_MSN

Minimum spanning network created using the software Arlequin

Population genetic dataset Anopheles sundaicus ITS2 alignment

DNA alignment of a fragment of ITS2 (ribosomal internal transcribed spacer 2) from Anopheles sundaicus s.l. used for biogeographical study. Individual haplotypes are submitted to GenBank Popset number 261599508 and details for each specimen are given in publication Supplementary table S1

Therapeutic coverage of ivermectin treatment in all study villages.

<p>The plots show the percentage of the overall population treated at each ivermectin round since mass ivermectin distribution began: <b>(A)</b> Asubende and <b>(B)</b> Agborlekame in the Brong-Ahafo Region; <b>(C)</b> Asukawkaw Ferry, <b>(D)</b> Dodi Papase and <b>(E)</b> Pillar 83 in the Volta Region; <b>(F)</b> Bosomase in the Western Region, and <b>(G)</b> Gyankobaa in the Ashanti Region. The dashed lines are the best fit least squares polynomial functions to the data, presented to facilitate visual inspection of the coverage trends. Biannual ivermectin distribution started in 2009 in Asubende, Agborlekame and Gyankobaa, whilst annual distribution has continued in the remaining villages.</p

Proportions of infected and infective flies by season and sampling method for Bosomase and Gyankobaa.

<p>Data and error bars are as in Fig 3, but excluding the 2006 Bellec-caught flies collected at Bosomase, as during the pilot study comparisons with other fly collection methods were not conducted.</p

Vector control and ivermectin treatment history, current strategy and infection levels per village.

<p>^<b>a</b> CMFL = community microfilarial load as defined in [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003688#pntd.0003688.ref019" target="_blank">19</a>], expressed as microfilariae (mf) per skin snip (ss)</p><p>^<b>b</b> CDTI = community-directed treatment with ivermectin</p><p>^<b>c</b> Flies infected with any <i>O</i>. <i>volvulus</i> larval stage</p><p>^<b>d</b> Flies infected with <i>O</i>. <i>volvulus</i> L3 larvae in heads and thoraces (the percentages of infected and infective flies were calculated from all flies, collected by both oviposition and host-seeking methods. Details of the total numbers dissected for each collection technique per village per season are presented in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003688#pntd.0003688.s002" target="_blank">S2 Table</a>)</p><p>^<b>e</b> pre-treatment baseline prevalence unknown, with 2000 the earliest date available; multiple ivermectin treatments from 1993 to 1997. In 1992, a mapping survey of the Onchocerciasis Control Programme in West Africa extension stated that ‘the site of Djodji presents the highest transmission potentials of the Eastern extension’[<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003688#pntd.0003688.ref095" target="_blank">95</a>].</p><p>Vector control and ivermectin treatment history, current strategy and infection levels per village.</p