Annotations of two examples about Markov process

In this paper, we discuss an incorrect example that a Markov process does not satisfy strong Markov property, and analyzes the reason of mistake. In the end, we point out it is not reasonable to define strong Markov property by using transition probability functions since transition probability functions might not be one and only

Figure_S1_pdf – Supplemental material for Dysregulation of miR-605-5p/STAT2 axis predicts an unfavorable survival in patients with gastric cancer

Supplemental material, Figure_S1_pdf for Dysregulation of miR-605-5p/STAT2 axis predicts an unfavorable survival in patients with gastric cancer by Yang Teng, Rong Tang and Shao-Jie Jiang in European Journal of Inflammation</p

Figure_S2_pdf – Supplemental material for Dysregulation of miR-605-5p/STAT2 axis predicts an unfavorable survival in patients with gastric cancer

Supplemental material, Figure_S2_pdf for Dysregulation of miR-605-5p/STAT2 axis predicts an unfavorable survival in patients with gastric cancer by Yang Teng, Rong Tang and Shao-Jie Jiang in European Journal of Inflammation</p

Supplementary_data – Supplemental material for Dysregulation of miR-605-5p/STAT2 axis predicts an unfavorable survival in patients with gastric cancer

Supplemental material, Supplementary_data for Dysregulation of miR-605-5p/STAT2 axis predicts an unfavorable survival in patients with gastric cancer by Yang Teng, Rong Tang and Shao-Jie Jiang in European Journal of Inflammation</p

Data_Sheet_1_The effects of cognitive behavioral therapy in women with polycystic ovary syndrome: A meta-analysis.ZIP

BackgroundCognitive behavioral therapy (CBT) has well-characterized benefits in alleviating diseases associated with depression, anxiety, and obesity, resulting in a marked improvement in the patient’s quality of life. There are some studies regarding the effects of CBT on patients with polycystic ovary syndrome (PCOS). However, there is still no report of a meta-analysis for systematic assessment.ObjectivesThis study aimed to evaluate the effectiveness of CBT in improving weight loss, anxiety, depression, life quality, compliance, and pregnancy outcomes in patients with PCOS.MethodsStudies regarding CBT related to PCOS in PubMed, Cochrane library, Embase, ClinicalTrials.gov, CNKI, and WANFANG DATA were searched for up to 19 November 2020. A random-effects model was used to perform a meta-analysis.ResultsEight trials regarding CBT compared with lifestyle modification and routine treatments were included. No differences in depression (SMD –1.11; 95% CI –2.28, 0.07; P > 0.05), body mass index (BMI) (SMD 0.88; 95% CI –0.94, 2.71; P > 0.05), or overall life quality (SMD 1.24; 95% CI –0.44, 2.92; P > 0.05) were evident between CBT and control groups; however, anxiety (SMD –1.12; 95% CI –2.1, –0.13; P ConclusionCBT exhibited obvious advantages in the alleviation of anxiety, improvement of quality of life in hirsutism, and increase of compliance and pregnancy rate in patients with PCOS. Larger and higher-quality randomized controlled trials are needed to clarify the role of CBT in PCOS.Systematic review registration[https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD42021225856].</p

Data_Sheet_2_The effects of cognitive behavioral therapy in women with polycystic ovary syndrome: A meta-analysis.PDF

BackgroundCognitive behavioral therapy (CBT) has well-characterized benefits in alleviating diseases associated with depression, anxiety, and obesity, resulting in a marked improvement in the patient’s quality of life. There are some studies regarding the effects of CBT on patients with polycystic ovary syndrome (PCOS). However, there is still no report of a meta-analysis for systematic assessment.ObjectivesThis study aimed to evaluate the effectiveness of CBT in improving weight loss, anxiety, depression, life quality, compliance, and pregnancy outcomes in patients with PCOS.MethodsStudies regarding CBT related to PCOS in PubMed, Cochrane library, Embase, ClinicalTrials.gov, CNKI, and WANFANG DATA were searched for up to 19 November 2020. A random-effects model was used to perform a meta-analysis.ResultsEight trials regarding CBT compared with lifestyle modification and routine treatments were included. No differences in depression (SMD –1.11; 95% CI –2.28, 0.07; P > 0.05), body mass index (BMI) (SMD 0.88; 95% CI –0.94, 2.71; P > 0.05), or overall life quality (SMD 1.24; 95% CI –0.44, 2.92; P > 0.05) were evident between CBT and control groups; however, anxiety (SMD –1.12; 95% CI –2.1, –0.13; P ConclusionCBT exhibited obvious advantages in the alleviation of anxiety, improvement of quality of life in hirsutism, and increase of compliance and pregnancy rate in patients with PCOS. Larger and higher-quality randomized controlled trials are needed to clarify the role of CBT in PCOS.Systematic review registration[https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD42021225856].</p

Data_Sheet_1_Microbiome of Co-cultured Fish Exhibits Host Selection and Niche Differentiation at the Organ Scale.PDF

Fish are the most widespread aquaculture species and maintain complex associations with microbial consortiums. However, the ecology of these associations present in multiple microhabitats in fish remains elusive, especially on the microbial assembly in fish external (skin and gill) and internal (stomach and intestine) niches, and the relationship with the rearing environment. To understand host dependence and niche differentiation of organ-specific microbiome signatures using a 16S rRNA gene-based sequencing technique, we systematically provided characterizations of a comparative framework relevant to the microbiome of stomach, regional intestine, skin, and gill in two important farmed fish species, herbivorous grass carp (Ctenopharyngodon idella) and carnivorous southern catfish (Silurus meridionalis), and of the rearing water. The different feeding habits of grass carp and southern catfish showed a significant separation of microbial community structure, with great compositional differences across body sites within each species. Site-driven divergences relied on host species: the same types of microhabitats between grass carp and southern catfish harbored differential microbiome. Additionally, body sites had remarkably distinct communities and displayed lower alpha diversity compared to rearing water. Unexpectedly, the stomach of southern catfish had the highest microbial diversity in the digestive tract of the two co-cultured fish species. For external sites within each species, a higher diversity occurred in gill of grass carp and in skin of southern catfish. Our results unveil different topographical microbiome signatures of the co-cultured species, indicating host selection in individual-level microbial assemblages and niche differentiation at the organ scale. This work represents a foundation for understanding the comprehensive microbial ecology of cohabiting farmed fish, suggesting potential applications associated with fish microbiome that urgently needs to be assessed in polycultured operations in aquaculture.</p

Data_Sheet_2_Genome Analysis and Description of Three Novel Diazotrophs Geomonas Species Isolated From Paddy Soils.xlsx

Five strictly anaerobic strains, designated RG2T, RG3, RG10T, RF4T, and RG29, were isolated from paddy soils in China. Strains RG2T, RF4T, RG10T, RG3, and RG29 grew at temperatures ranging 5–42°C and pH ranging 5.5–8.5. Strains RG2T, RF4T, RG3, and RG29 could tolerate NaCl up to 0–0.7% (w/v) while strain RG10T could tolerate NaCl up to 0–0.8% (w/v). The isolated strains showed the highest 16S rRNA gene sequence similarities to the type strains of Geomonas terrae Red111T and Geomonas paludis Red736T. In phylogenetic (based on 16S rRNA gene sequence) and phylogenomic trees, strains clustered with the members of the genus Geomonas. Menaquinone-8 was the predominant quinone present in all strains. The major fatty acid profiles of all strains were C15:1 ω6c, C16:0, iso-C15:0, and Summed Feature 3. The digital DNA–DNA hybridization (dDDH) and average nucleotide identity (ANI) values between the isolated strains and the closely related Geomonas species were lower than the cutoff value (ANI 95–96% and dDDH 70%) for prokaryotic species delineation. Based on physiological, biochemical, and chemotaxonomic properties, strains RG2T, RG10T, and RF4T could easily be differentiated with the members of the genus Geomonas. Additionally, all the isolated strains possessed nifHDK clusters and catalytic compartments of nitrogenase. Based on the above results, the isolated five strains represent three novel species of the genus Geomonas, for which the names Geomonas oryzisoli sp. nov., Geomonas subterranea sp. nov., and Geomonas nitrogeniifigens sp. nov. are proposed. The type strains are RG10T (= GDMCC1.2537T = KCTC 26318T), RG2T (= GDMCC1.2536T = KCTC 25317T), and RF4T (= GDMCC 1.2547T = KCTC 25316T).</p

Obstetric and neonatal outcomes by BMI category in women with PCOS.

Obstetric and neonatal outcomes by BMI category in women with PCOS.</p