Evaluation of time-series registration methods in dynamic area telethermometry for breast cancer detection

Automated motion reduction in 3D dynamic infrared imaging is on demand in many applications. Few methods for registering time-series dynamic infrared frames have been proposed. Almost all such methods are feature based algorithms requiring manual intervention. We apply different automated registration methods based on spatial displacement to 11 datasets of Breast Dynamic Infrared Imaging (DIRI) and evaluate the results in terms of both the image similarity and anatomical consistency of the transformation. The aim is to optimize the registration strategy for breast DIRI in order to improve the spectral analysis of temperature modulation; thus facilitating the acquisition procedure in a Dynamic Area Telethermometry framework. The results show that symmetric diffeomorphic demons registration outperforms both warped frames similarity and smoothness of deformation fields; hence proving effective for time-series dynamic infrared registratio

Evaluation of time-series registration methods in dynamic area telethermometry for breast cancer detection

Automated motion reduction in 3D dynamic infrared imaging is on demand in many applications. Few methods for registering time-series dynamic infrared frames have been proposed. Almost all such methods are feature based algorithms requiring manual intervention. We apply different automated registration methods based on spatial displacement to 11 datasets of Breast Dynamic Infrared Imaging (DIRI) and evaluate the results in terms of both the image similarity and anatomical consistency of the transformation. The aim is to optimize the registration strategy for breast DIRI in order to improve the spectral analysis of temperature modulation; thus facilitating the acquisition procedure in a Dynamic Area Telethermometry framework. The results show that symmetric diffeomorphic demons registration outperforms both warped frames similarity and smoothness of deformation fields; hence proving effective for time-series dynamic infrared registration

Pelvic ring fractures: External fixation comparative numerical structural analysis

External fixation (EF) is commonly practiced for pelvic ring fractures management. Many parameters influence mechanical performances of external fixators. Our virtual 3D model of the pelvic ring introduces the advantage of differentiating the mechanical properties of cortical and cancellous bone along with the complex boundary conditions of major ligaments. We assessed stiffness variations by increasing fixator pins depth and we evaluated dislocation related to load intensity and sitting angle

Unveiling Glutamate Dynamics: Cognitive Demands in Human Short-Term Memory Learning Across Frontal and Parieto-Occipital Cortex: A Functional MRS Study.

Background: Acquiring new knowledge necessitates alterations at the synaptic level within the brain. Glutamate, a pivotal neurotransmitter, plays a critical role in these processes, particularly in learning and memory formation. Although previous research has explored glutamate’s involvement in cognitive functions, a comprehensive understanding of its real-time dynamics remains elusive during memory tasks. Objective: This study aimed to investigate glutamate modulation during memory tasks in the right Dorsolateral Prefrontal Cortex (DLPFC) and parieto-occipital regions using functional Magnetic Resonance Spectroscopy (fMRS). Material and Methods: This experimental research applied fMRS acquisition concurrently with a modified Sternberg’s verbal working memory task for fourteen healthy right-handed participants (5 females, mean age=30.64±4.49). The glutamate/total-creatine (Glu/tCr) ratio was quantified by LCModel in the DLPFC and parieto-occipital voxels while applying the tissue corrections. Results: The significantly higher Glu/tCr modulation was observed during the task with a trend of increased modulation with memory load in both the DLPFC (19.9% higher, P-value=0.018) and parieto-occipital (33% higher, P-value=0.046) regions compared to the rest. Conclusion: Our pioneering fMRS study has yielded groundbreaking insights into brain functions during S-term Memory (STM) and learning. This research provides valuable methodological advancements for investigating the metabolic functions of both healthy and disordered brains. Based on the findings, cognitive demands directly correlate with glutamate levels, highlighting the neurochemical underpinnings of cognitive processing. Additionally, the obtained results potentially challenge the traditional left-hemisphere-centric model of verbal working memory, leading to the deep vision of hemispheric contributions to cognitive functions

Reviews of the three essential elements of intensive cities: Compactness, Convenience and safety

Cities are energy-using systems in their own right, and they can use energy in dramatically more or less efficient ways. Hence urban settlement forms could have a disproportionately large effect over the Energy consumption and consequently on any effective long-term strategy for reducing C02 greenhouse gases and emission in atmosphere. This paper demonstrates through the study case of Barcelona, how to transform an existing neighborhood into a lower energy consumption and better performing system. Based on IMM (Integrated Modification Methodology) the research discusses how the urban system performance could be optimized, expanding the energy efficiency goals from buildings to the urban scale. With available an average solar radiation of about 1500 kWh/m2/year city of Barcelona has a potential to produce a significant amount of energy. Then possible mitigating solution for the Urban Heat Island effect has been considered. In this approach, the city of Barcelona, considered as a Complex Adaptive System, has been transformed with a symbiotic integration, of built-up mass layer; open spaces, streets, etc. layer; land use layer; Transportation and Mobility Layer, in order to improve the sustainability as well the living conditions, comfort and health for inhabitants in the urban and building environment. A cluster of buildings in the Eixample neighborhood has been grouped together to be the subject of potential solar power installations and associated together with the UHI (Urban Heat Island) mitigation method and then retrofitte