85 research outputs found
A Living, Breathing Revolution: How Libraries Can Use “Living Archives� to Support, Engage, and Document Social Movements
IFLA World Library and Information Congress paper in Singapore. Published in IFLA Sage JournalWhere does and should the future of libraries lie? What were once concrete, brick, and glass structures have since become a third place where community, art, and culture reside. What is next? The #searchunderoccupy exhibit in the Sheila C. Johnson Design Center in New York City is a “living archive� that visually displays the creative and critical responses of the New School’s student community to the Occupy Wall Street movement. It is composed not only of elements such as video, photographs, audio and performance projects, but also text-based works such as live feed tag clouds,
posters, and blogs. By their very nature, libraries are poised to become forces for social change and using this exhibit as an example, libraries themselves can show the life of their communities by putting their responses on display to support their involvement in social movements, engage others, and document for the future. There are many iterations of the living archive in libraries such as the digitization of audio-visual materials or allowing people to share their memories, knowledge, photos
and opinions through a virtual space. The closest to the #searchunderoccupy exhibit example is capturing the activities and conversations of designer William McDonough for the Stanford University libraries. Unlike these projects, the New School’s method allows for a greater range of self-expression through visual mediums and accounts for the technology of today. Social media is what has helped spread the social movements of the current generation and with its ever changing nature, this version of a living archive presents a future library full of infinite possibilities
Recycling the First-Year One-Shot Workshop: Using Interactive Technology to Flip the Classroom
Connect with your Users: Usability Testing and How User Experience May Actually Work for You
For a library, User Experience (UX) refers to studying the emotions and attitudes of its users regarding the library building, website, or services. This can be executed through usability testing, which allows you to truly learn how users experience the library in all its forms. In this poster, a library system conducted a pilot project, a usability test, to research optimal staffing configurations with the goal of developing a sustainable UX strategy. A task force identified and tested a webpage common to both libraries in the two-library system - the Database List. Faculty and student users were tested and recorded as they completed various tasks using the original Database List and then subsequent redesigned versions. As a result of the study, the Database List was redesigned, personas - fictional characters of users created from actual user data- were developed, and the task force submitted recommendations for the best staffing model for sustainable UX. The presenters will outline the methods and tools used for the usability study, with the benefits and drawbacks of the different staffing models, and exhibit the findings of the project. This poster is a must-see for anyone who is interested in the best way to implement UX in their library
Thermal Performance Testing of EMU and CSAFE Liquid Cooling Garments
Future exploration missions require the development of a new liquid cooling garment (LCG) that offers greater system reliability, is more comfortable, and maximizes thermal performance. To inform the development of a future LCG a thermal performance test was conducted to evaluate three factors: (1) the effect of the thermal comfort undergarment (TCU) on tactile and thermal comfort, (2) the comparable thermal performance of an CSAFE developed engineering evaluation unit (EEU) LCG, which uses a commercial-off-the-shelf (COTS) wicking garment as the base, and (3) the performance of a torso or upper body only LCG configuration to evaluate a proposed auxiliary loop configuration. To evaluate the thermal performance of each configuration a metabolic suit test was conducted, utilizing suited subjects to generate metabolic heat by walking on a treadmill at various speeds. Three (3) test subjects of similar height and weight produced a metabolic load for five tests by either resting (300-600 BTU/hr), walking at a slow pace (1200 BTU/hr), and walking at a brisk pace (2200 BTU/hr). During the test, data was collected that would allow us to track the heat transfer to the LCG and ventilation system to determine the thermal performance of the LCG configurations. Four different test configurations were tested, with one configuration tested twice. The test results show that the CSAFE EEU LCG and EMU LCG had comparable performance. The testing also showed that an auxiliary loop LCG, sized similarly to the shirt-only configuration, should provide adequate cooling for contingency scenarios. Finally, the testing showed the previous analysis that assumed a UA deterioration from the TCU was too conservative and the TCU may prove to be acceptable for future development with additional analysis and testing
Thermal Performance Testing of EMU and CSAFE Liquid Cooling Gannents
Future exploration missions require the development of a new liquid cooling garment (LCG) to support the next generation extravehicular activity (EVA) suit system. The new LCG must offer greater system reliability, optimal thermal performance as required by mission directive, and meet other design requirements including improved tactile comfort. To advance the development of a future LCG, a thermal performance test was conducted to evaluate: (1) the comparable thermal performance of the EMU LCG and the CSAFE developed engineering evaluation unit (EEU) LCG, (2) the effect of the thermal comfort undergarment (TCU) on the EMU LCG tactile and thermal comfort, and (3) the performance of a torso or upper body only LCG shirt to evaluate a proposed auxiliary loop. To evaluate the thermal performance of each configuration, a metabolic test was conducted using the Demonstrator Spacesuit to create a relevant test environment. Three (3) male test subjects of similar height and weight walked on a treadmill at various speeds to produce three different metabolic loads - resting (300-600 BTU/hr), walking at a slow pace (1200 BTU/hr), and walking at a brisk pace (2200 BTU/hr). Each subject participated in five tests - two wearing the CSAFE full LCG, one wearing the EMU LCG without TCUs, one wearing the EMU LCG with TCUs, and one with the CSAFE shirt-only. During the test, performance data for the breathing air and cooling water systems and subject specific data was collected to define the thermal performance of the configurations. The test results show that the CSAFE EEU LCG and EMU LCG with TCU had comparable performance. The testing also showed that an auxiliary loop LCG, sized similarly to the shirt-only configuration, should provide adequate cooling for contingency scenarios. Finally, the testing showed that the TCU did not significantly hinder LCG heat transfer, and may prove to be acceptable for future suit use with additional analysis and testing
“Do you want to build a snowman?�: Methods for Library Outreach and Collaboration
This session will review the following Online Librarian practices: embedded librarianship, online monthly workshops on demand, and collaborative service-learning courses. Three librarians from various North Carolina libraries will review their best practices and suggestions for implementation for the three practices. Participants will be encouraged to ask questions and take away the process to create their own need-specific programs.
Learning Objectives for the Session:
Explain the concept of “embedded librarianship� and how to implement a comprehensive strategy to market embedded librarianship and maintain collaborative faculty relationships.
Review the need and strategies for developing online monthly workshops and discuss the process for implementation.
What service-learning courses are and how they could be useful to libraries and how to implement a collaboration with a service-learning course
HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus
Endoplasmic reticulum (ER) stress is a condition in which the protein folding capacity of the ER becomes overwhelmed by an increased demand for secretion or by exposure to compounds that disrupt ER homeostasis. In yeast and other fungi, the accumulation of unfolded proteins is detected by the ER-transmembrane sensor IreA/Ire1, which responds by cleaving an intron from the downstream cytoplasmic mRNA HacA/Hac1, allowing for the translation of a transcription factor that coordinates a series of adaptive responses that are collectively known as the unfolded protein response (UPR). Here, we examined the contribution of IreA to growth and virulence in the human fungal pathogen Aspergillus fumigatus. Gene expression profiling revealed that A. fumigatus IreA signals predominantly through the canonical IreA-HacA pathway under conditions of severe ER stress. However, in the absence of ER stress IreA controls dual signaling circuits that are both HacA-dependent and HacA-independent. We found that a ΔireA mutant was avirulent in a mouse model of invasive aspergillosis, which contrasts the partial virulence of a ΔhacA mutant, suggesting that IreA contributes to pathogenesis independently of HacA. In support of this conclusion, we found that the ΔireA mutant had more severe defects in the expression of multiple virulence-related traits relative to ΔhacA, including reduced thermotolerance, decreased nutritional versatility, impaired growth under hypoxia, altered cell wall and membrane composition, and increased susceptibility to azole antifungals. In addition, full or partial virulence could be restored to the ΔireA mutant by complementation with either the induced form of the hacA mRNA, hacAi, or an ireA deletion mutant that was incapable of processing the hacA mRNA, ireAΔ10. Together, these findings demonstrate that IreA has both HacA-dependent and HacA-independent functions that contribute to the expression of traits that are essential for virulence in A. fumigatus
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated with various adult diseases. Using 1000 Genomes Project-imputed genotype data in up to similar to 370,000 women, we identify 389 independent signals (P <5 x 10(-8)) for age at menarche, a milestone in female pubertal development. In Icelandic data, these signals explain similar to 7.4% of the population variance in age at menarche, corresponding to similar to 25% of the estimated heritability. We implicate similar to 250 genes via coding variation or associated expression, demonstrating significant enrichment in neural tissues. Rare variants near the imprinted genes MKRN3 and DLK1 were identified, exhibiting large effects when paternally inherited. Mendelian randomization analyses suggest causal inverse associations, independent of body mass index (BMI), between puberty timing and risks for breast and endometrial cancers in women and prostate cancer in men. In aggregate, our findings highlight the complexity of the genetic regulation of puberty timing and support causal links with cancer susceptibility
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