Height and Weight by among girls aged 5–6 in the ABBY Project.

<p>(Upper) Lowess smoother of height and age for each group compared with the UK 1990 Growth References, (Lower) Lowess smoother of weight and age for each group compared with the UK 1990 Growth References.</p

Sample characteristics of ABBY project participants; reported as mean (SD) for continuous variables or number and percent for categorical variables.

†<p>indicates statistical difference between Sylheti and the other group at the p<0.05 cut off.</p><p>Sample characteristics of ABBY project participants; reported as mean (SD) for continuous variables or number and percent for categorical variables.</p

Hazard ratios (95% C I) of adrenarche onset among girls <9.5 years adjusted for height, weight, BMI, and waist circumference.

<p>Hazard ratios (95% C I) of adrenarche onset among girls <9.5 years adjusted for height, weight, BMI, and waist circumference.</p

Salivary DHEAS pg/ml by age groups in Sylheti, first-generation, second-generation and European girls, aged 5-16 years.

†<p>indicates statistical difference between Sylheti and first-generation girls at the p<0.05 cut off.</p><p>Salivary DHEAS pg/ml by age groups in Sylheti, first-generation, second-generation and European girls, aged 5-16 years.</p

Lowess smoother of the log of DHEAS by age among all girls Aged 5–16 years.

<p>Triangle shows inflection point where log salivary DHEAS reaches 5.5–6 pg/ml, signifying the clinical threshold for adrenarche.</p

Plot of the density function of beta distributions parameterized by mean and heterogeneity factor .

<p>On each subplot the density is shown for two choices of namely  = 0.2 (solid line) and  = 0.25 (dotted lines).</p

Principal components plots of AABC and selected HapMap samples.

<p>Principal components plots of AABC and selected HapMap samples.</p

Quantile-quantile plot of p-values from association tests in the hypothesized case-control study in which cases from the CBCS and controls from the MEC are used.

<p>The plotted values indicate adjustment for 0 (uncorrected heavy solid line), 1 (dashed line), 10 (dotted line) and 200 (thin solid line) eigenvectors, by using these components in the calculation of .</p

Plot of estimate of proportion of African ancestry from STRUCTURE by participating AABC study.

<p>Plot of estimate of proportion of African ancestry from STRUCTURE by participating AABC study.</p

Plot of non-centrality parameter for the Bourgain test for a case-control study using two incompletely admixed populations as sources of cases and controls respectively.

<p>The parameters chosen refer to a test of a variant associated with disease which has 40 percent overall allele frequency and which is associated with a 10 percent difference in frequency between cases and controls (OR = 1.5 per copy). Cases are assumed to have average admixture percentage of 20 percent and controls 25 percent. The within population heterogeneity is specified by a single common heterogeneity parameter as used in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1001096#pgen-1001096-g001" target="_blank">Figure 1</a>.</p