556 research outputs found

    Thermodynamics of rotating black branes in (n+1)(n+1)-dimensional Einstein-Born-Infeld gravity

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    We construct a new class of charged rotating solutions of (n+1)(n+1)-dimensional Einstein-Born-Infeld gravity with cylindrical or toroidal horizons in the presence of cosmological constant and investigate their properties. These solutions are asymptotically (anti)-de Sitter and reduce to the solutions of Einstein-Maxwell gravity as the Born-Infeld parameters goes to infinity. We find that these solutions can represent black branes, with inner and outer event horizons, an extreme black brane or a naked singularity provided the parameters of the solutions are chosen suitably. We compute temperature, mass, angular momentum, entropy, charge and electric potential of the black brane solutions. We obtain a Smarr-type formula and show that these quantities satisfy the first law of thermodynamics. We also perform a stability analysis by computing the heat capacity and the determinant of Hessian matrix of mass with respect to its thermodynamic variables in both the canonical and the grand-canonical ensembles, and show that the system is thermally stable in the whole phase space.Comment: 12 pages, one figur

    Entry into primary care-based buprenorphine treatment is associated with identification and treatment of other chronic medical problems

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    BACKGROUND: Buprenorphine is an effective treatment for opioid dependence that can be provided in a primary care setting. Offering this treatment may also facilitate the identification and treatment of other chronic medical conditions. METHODS: We retrospectively reviewed the medical records of 168 patients who presented to a primary care clinic for treatment of opioid dependence and who received a prescription for sublingual buprenorphine within a month of their initial visit. RESULTS: Of the 168 new patients, 122 (73%) did not report having an established primary care provider at the time of the initial visit. One hundred and twenty-five patients (74%) reported at least one established chronic condition at the initial visit. Of the 215 established diagnoses documented on the initial visit, 146 (68%) were not being actively treated; treatment was initiated for 70 (48%) of these within one year. At least one new chronic medical condition was identified in 47 patients (28%) during the first four months of their care. Treatment was initiated for 39 of the 54 new diagnoses (72%) within the first year. CONCLUSIONS: Offering treatment for opioid dependence with buprenorphine in a primary care practice is associated with the identification and treatment of other chronic medical conditions

    Heavy Metals Residue in Cultivated Mango Samples from Iran

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    Background: Heavy metals contaminations are recognized as the serious risk to our environment. The aim of the present study was to analyze heavy metals residue in cultivated mango samples from Iran. Methods: Totally, 72 mango samples were randomly collected among six different mango genotypes cultivated in Southern Iran from June to July 2015. Lead, chromium, cadmium, and arsenic were determined using an atomic absorption spectrometer. Analysis of variance was performed with SAS 9.0. Descriptive statistics, multivariate analysis, and Duncan multiple range tests were done with a significance level of p<0.05. Results: Measurement of heavy metals in all the mango samples showed various level ranges of lead (0.008-0.05 ppm), chromium (0.01-0.1 ppm), cadmium (0.002-0.014 ppm), and arsenic (0.01-0.04 ppm). Heavy metal levels were significantly (p0.05) was seen between heavy metals residue and variety in genotypes of mango samples. Conclusion: The average amount of heavy metals residue in mango samples found in the current study were generally below the maximum acceptable levels indicating acceptable safety of these products

    Multi-locus sequence type analysis of Shigellas pp. Isolates from Tehran, Iran

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    Background and Objectives: Strains of Shigella spp. can cause shigellosis, or bacillary dysentery. That is a public health problem worldwide. The aim of this study was to describe the population structure and genetic relatedness of multidrug resistant S. sonnei and S. flexneri isolated during a one year period from children with diarrhea in Tehran, Iran. Materials and Methods: A total of 70 Shigella spp. were detected during the study period. Twenty MDR isolates of Shigella spp. were randomly selected and used in this study. Bacterial identification was performed by conventional biochemical and serological and confirmed by molecular method. After antimicrobial susceptibility testing, we used Multilocus sequence typing (MLST) for subtyping isolates. Results: We found 14 Shigella sonnei and 6 Shigella flexneri isolates. Results of MLST showed five sequence types (ST) (145, 152, 241, 245, 1502) and BURST analysis revealed the largest number of single locus variant (SLV) and highest frequency (FREQ) for ST152. ST 152 with nine members was predicted as the founder by BURST. Frequency for ST 1502 and ST 245 was four isolates and the least frequency was seen for ST 241 and 145 with one and two members, respectively. ST 145 and ST 245 were described as singletons in BURST. All isolates with ST145 and ST245 were identified as Shigella flexneri. Conclusion: Annual Multi locus sequence typing of MDR Shigella would help us in better understanding of dominant species and comparing our results with the same studies in other countries especially our neighbor countries in source tracking purposes. © Tehran University of Medical Science. All rights reserved

    Effects of benzo-α-pyren (BaP) on plasma levels of spermatogenesis related hormones (cortisol and testosterone) in functional male of yellowfin seabream, Acanthopagrus latus

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    The present study carried out to assess the effects of Benzo-α-Pyrene (BaP) as a serious member of Polycyclic Aromatic Hydrocarbons (PAH) on the plasma levels of cortisol and triiodothyronine (T3) hormones in male Seabream, Acanthopagrus latus (Sparidea). To assess the acute effects of BaP on the endocrine system, a group of fish was injected with dissolved BaP in sunflower oil (50mg/kg BaP in 2µg/l oil according to the body weight). Other fishes were injected with 2µg/l body weight as controls. Blood samples from both groups collected 3 hours after injection. In another protocol, the chronic effects of BaP on the plasma levels of cortisol and T3 were assessed. For this reason a group of fish was implanted with 50mg/kg BaP in 10µl/g coconut oil in respect to each fish body weight. As the previous protocol a control group was implanted with the same amount of oil without the BaP. Blood samples collected from both implanted groups (treatment and control) after 72 hours. According to the results, plasma levels of cortisol in yellowfin Seabream increased during both short time and long time exposure but T3 levels in the plasma decreased during the chronic stress of BaP exposure. It seems the cortisol levels are elevating to provide more energy requirement under the acute and chronic stress conditions by direct effect on glyconeogenesis and fast blood sugar level to be consumed by cells. T3 levels may be affected by inhibitory effect of Aryl hydrocarbon receptors (AhRs) which decreased it during long term exposure