Copper-Catalyzed Oxidative C–H Amination of Tetrahydrofuran with Indole/Carbazole Derivatives

A simple α-C–H amination of cyclic ether with indole/carbazole derivatives has been accomplished by employing copper­(II) chloride/bipy as the catalyst system. In the presence of the di-<i>tert</i>-butyl peroxide oxidant, cyclic ethers such as tetrahydrofuran, 1,4-dioxane, and tetrahydropyran successfully undergo C–H/N–H cross dehydrogenative coupling (CDC) with various carbazole or indole derivatives in good-to-excellent yields

Rh-Catalyzed Highly Enantioselective Hydroalkynylation Reaction of Norbornadiene Derivatives

The complexes of various Rh precusors with ferrocenyl chiral ligand (<i>R</i>,<i>S</i>)-Cy₂PF-PPh₂ were found effective catalysts for the asymmetric hydroalkynylation reaction of norbornadiene derivatives. When RhCl₃·3H₂O was employed, good yields (up to 98%) and high enantioselectivities (up to >99.9% <i>ee</i>) could be obtained for the reactions of a broad scope of substrates