sj-csv-1-sgo-10.1177_21582440241228696 – for Information Network Among Farmers: A Case Study in Ghana

sj-csv-1-sgo-10.1177_21582440241228696 for Information Network Among Farmers: A Case Study in Ghana by Qian Yu and Patience Pokuaa Gambrah in SAGE Open</p

sj-csv-2-sgo-10.1177_21582440241228696 – for Information Network Among Farmers: A Case Study in Ghana

sj-csv-2-sgo-10.1177_21582440241228696 for Information Network Among Farmers: A Case Study in Ghana by Qian Yu and Patience Pokuaa Gambrah in SAGE Open</p

Enantioselective Syntheses of Monotetrahydrofuran Annonaceous Acetogenins Tonkinecin and Annonacin Starting from Carbohydrates

The total synthesis of two mono-THF acetogenins, tonkinecin (1) and annonacin (2), is reported in full detail. Terminal acetylene 3 prepared from d-glucono-δ-lactone and asymmetric dihydroxylation was employed as a common intermediate for both targets 1 and 2. Pd(0)-catalyzed coupling reaction of 3 with vinyl iodides 4 and 5, the chiral centers of which were taken from d-xylose and S-(−)-ethyl lactate, afforded enyne 26 and 27, respectively. Selective hydrogenation of 26 or 27 with diimide followed by removal of MOM ethers completed the synthesis of 1. A coupling reaction between the lithium derivative of 3 and epoxide 6 in the presence of boron trifluoride etherate gave 42. Both chiral centers in epoxide 6 were taken from l-ascorbic acid. Subsequent catalytic hydrogenation and MOM protection led to 43b. Introduction of the butenolide moiety by aldol condensation of protected S-lactal followed by cleavage of all MOM ethers completed the synthesis of 2

DataSheet1_Preparation of Plasmonic Ag@PS Composite via Seed-Mediated In Situ Growth Method and Application in SERS.docx

The colloidal polystyrene (PS) was synthesized and decorated with silver nanoparticles (Ag NPs). The plasmonic Ag@PS nanocomposite was prepared by loading Ag NPs on PS microsphere through a seed-mediated in situ growth route. The property of Ag NPs deposited on the PS microsphere could be precisely controlled by adjusting the concentration of the chemicals used in the growth medium. The growth step is only limited by the diffusion of growing species in the growth media to the surface of the Ag seed. The Ag@PS prepared via the in situ growth method exhibited two advantages compared with the self-assembled PS/Ag. First, the high-density of Ag NPs were successfully deposited on the surface of PS as the electroless-deposited Ag seed process, which brings nearly three times SERS enhancement. Second, the rapid preparation process for in situ growth method (half an hour, 10 h for the self-assembled method). The PS/Ag could detect Nile blue A (NBA) down to 10–7 M by SERS. Furthermore, the plasmonic Ag@PS SERS substrate was used for pesticide identification. The on-site monitoring malachite green (MG) from fish was achieved by portable Raman spectrometer, and the limit of detection (LOD) was 0.02 ppm. The Ag@PS substrate has also shown capability for simultaneously sensing multiple pesticides by SERS.</p

Reorganized functional connectivity of language centers as a possible compensatory mechanism for basal ganglia aphasia

Primary Object: To investigate the functional connectivity (FC) of cortical language centers in patients who have regained fluent speech after basal ganglia aphasia and identify the possible compensatory mechanism. Methods & Procedures: A retrospective cohort of 12 patients and 17 healthy controls were studied using resting-state functional MRI (rs-fMRI). All patients suffered from an ischemic stroke with lesions confined to the basal ganglia and showed impaired language functions at admission. Seven patients had lesions in the left basal ganglia, three in the right, and two in both sides. The rs-fMRI was performed after the patients regained fluent speech. Broca’s area, Wernicke’s area, and their contralateral homologues were selected as the region-of-interest (ROI) for both voxel-wise and ROI-wise FC studies. Results: We discovered that the interhemispheric FC of the language centers (i.e. Broca’s area and Wernicke’s area) decreased and the intrahemispheric FC of the language centers increased in these patients who regained fluent speech after basal ganglia aphasia. Conclusions: We speculated that damages to the basal ganglia disrupted the cortico-subcortical circuits that facilitated the transhemispheric communications of language functions, resulting in decreased interhemispheric FC. Consequently, the intrahemispheric FC increased as a possible compensatory mechanism to restore the language functions.</p

Data_Sheet_1_Assessment of the prognostic value of preoperative high-sensitive troponin T for myocardial injury and long-term mortality for groups at high risk for cardiovascular events following noncardiac surgery: a retrospective cohort study.docx

BackgroundFew studies explored the association between high-sensitive cardiac troponin T (hs-cTnT) and long-term mortality for patients after surgery. This study was conducted to assess the association of hs-cTnT with long-term mortality and to investigate the extent to which this association is mediated via myocardial injury after noncardiac surgery (MINS).MethodsThis retrospective cohort study included all patients with hs-cTnT measurements who underwent non-cardiac surgery at Sichuan University West China Hospital. Data were collected from February 2018 and November 2020, with follow-up through February 2022. The primary outcome was all-cause mortality within 1 year. As secondary outcomes, MINS, length of hospital stay (LOS), and ICU admission were analyzed.ResultsThe cohort included 7,156 patients (4,299 [60.1%] men; 61.0 [49.0–71.0] years). Among 7,156 patients, there were 2,151 (30.05%) with elevated hs-cTnT(>14 ng/L). After more than 1 year of follow-up, more than 91.8% of mortality information was available. During one-year follow-up after surgery, there were 308 deaths (14.8%) with a preoperative hs-cTnT >14 ng/L, compared with 192 deaths (3.9%) with a preoperative hs-cTnT ConclusionPreoperative elevated hs-cTnT concentrations have a significant association with long-term mortality after noncardiac surgery, one-third of which may by accounted for by MINS.</p

Total Synthesis of (10<i>R</i>)- and (10<i>S</i>)-Corossolin: Determination of the Stereochemistry at C-10 of the Natural Corossolin and the Differential Toxicity toward Cancer Cells Caused by the Configuration at C-10

(10R) and (10S)-corossolin have been synthesized by coupling of the alkyne intermediate 18 with epoxide 27 or 29, respectively. Comparison of the physical data of both synthetic corossolins with those reported for the natural one shows that the configuration at C-10 of the natural corossolin is highly likely to be R. The R isomer is found to be 18 times as active as the S isomer in the preliminary in vitro tests against the B16BL6 cell line

Supramolecular Coordination Complexes with 5-Sulfoisophthalic Acid and 2,5-Bipyridyl-1,3,4-Oxadiazole: Specific Sensitivity to Acidity for Cd(II) Species

A series of CdII, CoII, NiII, and PbII mixed-ligand coordination complexes 1−8 based on 5-sulfoisophthalic acid (H3sip) and the bent dipyridyl ligand 2,5-bis(3-pyridyl)-1,3,4-oxadiazole (3-bpo) or its 4-pyridyl N-donor analogue (4-bpo) have been synthesized and fully characterized by IR spectra, microanalyses, and single crystal and powder X-ray diffraction techniques. The significant pH effect on assembly of the CdII complexes 1−4 has been demonstrated, which leads to the formation of distinct crystalline products, whereas the CoII, NiII, and PbII systems 5−8 are independent to pH condition of the synthetic reaction. Complexes 1−8 display various coordination motifs with different existing forms, conformations, and coordination modes of the organic ligands. Further, extended supramolecular networks are constructed via secondary interactions such as hydrogen-bonding and aromatic stacking. Solid-state properties of thermal stability and fluorescence for these crystalline materials are also presented

Supramolecular Coordination Complexes with 5-Sulfoisophthalic Acid and 2,5-Bipyridyl-1,3,4-Oxadiazole: Specific Sensitivity to Acidity for Cd(II) Species

A series of CdII, CoII, NiII, and PbII mixed-ligand coordination complexes 1−8 based on 5-sulfoisophthalic acid (H3sip) and the bent dipyridyl ligand 2,5-bis(3-pyridyl)-1,3,4-oxadiazole (3-bpo) or its 4-pyridyl N-donor analogue (4-bpo) have been synthesized and fully characterized by IR spectra, microanalyses, and single crystal and powder X-ray diffraction techniques. The significant pH effect on assembly of the CdII complexes 1−4 has been demonstrated, which leads to the formation of distinct crystalline products, whereas the CoII, NiII, and PbII systems 5−8 are independent to pH condition of the synthetic reaction. Complexes 1−8 display various coordination motifs with different existing forms, conformations, and coordination modes of the organic ligands. Further, extended supramolecular networks are constructed via secondary interactions such as hydrogen-bonding and aromatic stacking. Solid-state properties of thermal stability and fluorescence for these crystalline materials are also presented

Comprehensive Study of the Interaction and Mechanism between Bistetrazole Ionic Salt and Ammonium Nitrate Explosive in Thermal Decomposition

Bistetrazole energetic ionic salts, such as dihydroxylammonium 5,5′-bistetrazole-1,1′-diolate (TKX-50) and diamino 5,5′-bistetrazole-1,1′-diolate (ABTOX), are new insensitive materials and have great potential applications because of their good energy and safety performance. Prior to pure explosive preparation into PBX, the interactions between the components must be evaluated. Examination of interactions between bistetrazole ionic salt and ammonium nitrate explosive in thermal decomposition is beneficial in revealing the interactive mechanism of these two kinds of energetic materials in decomposition, as well as in the evaluation of compatibility, safety, and reliability of PBX explosive based on TKX-50, ABTOX, HMX, and RDX. Herein, the thermal decomposition behavior of TKX-50/HMX, ABTOX/HMX, TKX-50/RDX, and ABTOX/RDX is investigated. Ammonium nitrate explosives can significantly reduce the thermal decomposition peak temperature of the bistetrazole ionic salt. For example, HMX reduces the decomposition peak temperatures of the first and second stages of TKX-50 by 4 and 15 K, respectively, and ABTOX by 26 K (heating rate 5 K min–1). Utilizing HMX, the interaction mechanism between ammonium nitrate explosives and bistetrazole ionic material in thermal decomposition was investigated in detail. Changes in gas products, morphology, and molecular structure of the materials during decomposition show that TKX-50 induces HMX to HONO elimination decomposition, while ABTOX induces HMX open-loop decomposition. Furthermore, the heat generated by HMX decomposition accelerates the decomposition of TKX-50 and ABTOX. Moreover, the melting characteristics of HMX and molten product formation in the decomposition of TKX-50 and ABTOX promote the interaction between solid phase materials. Additionally, using calculation simulation, we confirmed that NH3OH+ in TKX-50 transfers hydrogen to the HMX nitro group, resulting in the HONO elimination of HMX, while the bistetrazole N-oxide anion in ABTOX and its alkaline decomposition intermediate product captures the hydrogen of the HMX main ring and causes HMX ring-opening decomposition