24 research outputs found

    Co-evaporation of Co-Cr at intermediate oblique incidence

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    The Co-evaPoration technique has been used for deposition of Co-Cr layers. Deposition has been done under intermediate angle of incidence of opposing vapour streams. The layers showed a single Phase hcP poly-crystalline structure. The (002) plane turned out to be tilted towards the direction of the CO source. The layers showed good perpendicular magnetic behaviour although the magnetic anisotropy axis was also inclined towards the Co-source. Because of the opposing angle of incidence for Co and Cr atoms, a process-induced segregation takes place which causes a relative high coercivity also at low Process temFeratures. A simple model for the segregation effect can explain the relation between the existance of a non-magnetic region and an increased coercivity of th Co-Cr film

    Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

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    BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

    Non-AIDS defining cancers in the D:A:D Study-time trends and predictors of survival : a cohort study

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    BACKGROUND:Non-AIDS defining cancers (NADC) are an important cause of morbidity and mortality in HIV-positive individuals. Using data from a large international cohort of HIV-positive individuals, we described the incidence of NADC from 2004-2010, and described subsequent mortality and predictors of these.METHODS:Individuals were followed from 1st January 2004/enrolment in study, until the earliest of a new NADC, 1st February 2010, death or six months after the patient's last visit. Incidence rates were estimated for each year of follow-up, overall and stratified by gender, age and mode of HIV acquisition. Cumulative risk of mortality following NADC diagnosis was summarised using Kaplan-Meier methods, with follow-up for these analyses from the date of NADC diagnosis until the patient's death, 1st February 2010 or 6 months after the patient's last visit. Factors associated with mortality following NADC diagnosis were identified using multivariable Cox proportional hazards regression.RESULTS:Over 176,775 person-years (PY), 880 (2.1%) patients developed a new NADC (incidence: 4.98/1000PY [95% confidence interval 4.65, 5.31]). Over a third of these patients (327, 37.2%) had died by 1st February 2010. Time trends for lung cancer, anal cancer and Hodgkin's lymphoma were broadly consistent. Kaplan-Meier cumulative mortality estimates at 1, 3 and 5 years after NADC diagnosis were 28.2% [95% CI 25.1-31.2], 42.0% [38.2-45.8] and 47.3% [42.4-52.2], respectively. Significant predictors of poorer survival after diagnosis of NADC were lung cancer (compared to other cancer types), male gender, non-white ethnicity, and smoking status. Later year of diagnosis and higher CD4 count at NADC diagnosis were associated with improved survival. The incidence of NADC remained stable over the period 2004-2010 in this large observational cohort.CONCLUSIONS:The prognosis after diagnosis of NADC, in particular lung cancer and disseminated cancer, is poor but has improved somewhat over time. Modifiable risk factors, such as smoking and low CD4 counts, were associated with mortality following a diagnosis of NADC

    Improved properties of CoCr made by co-evaporation

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    CoCr was made by a co-evaporation process. Good properties could be obtained by applying a Ti seedlayer. Furtheron we confirmed that "process-induced" segregation, resulting in increased perpendicular coercivity, can be controlled by angle of incidence

    Simulation model for a silicon Hall sensor in an absolute digital position detection system

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    The performance of a digital position detection system with silicon Hall sensors for the detection of coded absolute position data has been investigated. The position information is fixed in one single track as a maximum length sequence of bits by means of longitudinal saturation recording in a hard-magnetic layer. The Hall elements are positioned with their surface parallel to the hard-magnetic layer.\ud \ud An efficient computer simulation model has been realized which calculates the response of a Hall element in the fringing field. The computed results are compared with experimental data on Hall elements which were realised using MOS-IC technology. The simulation model appeared to be sufficiently accurate for a first-order estimation of the performance of an absolute position detection system on the basis of silicon Hall elements. The resolution which can be realized depends strongly on the noise level in the elements and will be of the order of a few hundred μm

    Factors Influencing Interventions on Behalf of Victims of Bullying: A Counterfactual Approach to the Social Cognitions of Outsiders and Defenders

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    While both outsiders and defenders have antibullying attitudes, only defenders have the reputation to defend victims. However, outsiders—despite their reputation of avoiding involvement in bullying—do receive some defender nominations and thus defend victims at least occasionally. This study investigated the relationship between these behavioral reputations and social-cognitive antecedents of students’ provictim intervention decision: Is provictim intervention related to a cost-reward analysis or to an analysis based on the presence and reactions of others? A sample of 489 Dutch early adolescents ((Formula presented.

    Differential personality correlates of early adolescents' bullying-related outsider and defender behavior

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    This study investigated personality correlates of early adolescents’ tendency to either defend victims of bullying or to avoid involvement in bullying situations. Participants were 591 Dutch fifth- and sixth-grade students ((Formula presented.) = 11.42 years). Hierarchical regression models were run to predict these students’ peer-reported defender and outsider behavior by their self-reported Big Five and Reinforcement Sensitivity scores. Agreeableness (i.e., politeness) positively predicted both behaviors. Emotional stability (i.e., impulse control) positively and extraversion (i.e., dominance) negatively predicted only outsider behavior. Finally, punishment sensitivity positively and reward sensitivity negatively predicted only outsider behavior. While agreeableness seems conducive to executing provictim interventions, lacking in dominance and a strong impulse control make actively avoiding involvement in bullying situations more likely. The latter also holds for early adolescents who are afraid of punishment and unresponsive to rewards. The findings suggest that antibullying interventions aiming at promoting defending in outsiders need to take the influence of personality into account

    Children's intervention strategies in situations of victimization by bullying: Social cognitions of outsiders versus defenderd.

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    This study examined the social cognitions of outsiders and defenders about intervening in situations of victimization by bullying. Do outsiders and defenders behave differently in victimization situations because of differences in competence beliefs, or because of a selectivity effect in intervening? These issues were examined in a sample of 102 outsiders and 107 defenders who were classified into these bullying roles through a peer-nomination procedure out of a total sample of 761 10- to 14-year-old Dutch children. These children were presented with imaginary victimization events. They answered questions about their cognitions and self-efficacy beliefs about intervening in victimization situations and about handling such situations. Outsiders, compared to defenders, claimed to intervene indirectly in victimization situations rather than directly. Defenders, compared to outsiders, claimed to intervene directly in victimization situations rather than indirectly. Both outsiders and defenders claimed to be more likely to intervene when a friend was being victimized than when a neutral classmate was being victimized. Outsiders and defenders did not differ in their self-efficacy for indirect intervention, but only defenders claimed a high self-efficacy for direct intervention. Both outsiders and defenders claimed to benefit from direct help when they themselves are victimized, but only outsiders also reported to need indirect help. The results suggest that outsiders and defenders behave differently in victimization situations because of differences in competence beliefs rather than because of a selectivity effect. More generally, the results suggest that not only defenders but also outsiders have the intention to help children who are being bullied. However, outsiders' anti-bullying attempts are likely to be indirect and less firm than those of defenders. © 2013 Society for the Study of School Psychology
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