Body Temperature files

Text files containing the body temperature recordings from individual female laboratory mice housed singly, in pairs, or in groups of 5 in laboratory cages. Temperature is in Celsius (C = Celsius) and was recorded using iButton temperature dataloggers. Each line contains the date and time of the body temperature recording. The first number in the filename represents the mouse ID for that file. Singlets: SC4.1, SC10.2, SC17.4, SC35.8, SC41.10, SC43.10, SC54.12, SC56.13, SC61.14. Pairs: (SC2.1 with SC19.5), (SC7.2 with SC16.4), (Sc5.1 with SC22.5), (SC27.1 with SC60.14), (SC33.8 with SC45.11), (SC39.9 with SC59.13), (SC44.10 with SC50.12), (SC30.7 with SC46.11). Quintets: (SC3.1, SC6.2, SC13.3, SC15.4, SC23.5), (SC8.2, SC11.3, SC14.4, SC21.5, SC25.6), (SC1.1, SC9.2, SC18.4, SC20.5, SC24.6), (SC26.7, SC38.9, SC42.10, SC49.11, SC52.12), (SC31.8, SC40.9, SC47.11, SC51.12, SC58.13), (SC34.8, SC36.9, SC53.12, SC55.13, SC62.14), (SC29.7, SC32.8, SC37.9, SC48.11, SC57.13

Datasheet1_Comparison of oxygen supplementation in very preterm infants: Variations of oxygen saturation features and their application to hypoxemic episode based risk stratification.pdf

BackgroundOxygen supplementation is commonly used to maintain oxygen saturation (SpO2) levels in preterm infants within target ranges to reduce intermittent hypoxemic (IH) events, which are associated with short- and long-term morbidities. There is not much information available about differences in oxygenation patterns in infants undergoing such supplementations nor their relation to observed IH events. This study aimed to describe oxygenation characteristics during two types of supplementation by studying SpO2 signal features and assess their performance in hypoxemia risk screening during NICU monitoring.Subjects and methodsSpO2 data from 25 infants with gestational age ResultsWhile most SpO2 measures remained comparable during both supplementations, signal irregularity and complexity were elevated while on OE, pointing to more volatility in oxygen saturation during this supplementation mode. In addition, SpO2 variability measures exhibited early prognostic value in discriminating infants at higher risk of critically many IH events. Poincare plot variability at lag 1 had AUROC of 0.82, 0.86, 0.89 compared to 0.63, 0.75, 0.81 for the IH number, a clinical parameter at observation times of 30 min, 1 and 2 h, respectively. Multivariate models with two features exhibited validation AUROC > 0.80, F1 score > 0.60 and specificity >0.85 at observation times ≥ 1 h. Finally, we proposed a framework for risk stratification of infants using a cumulative risk score for continuous monitoring.ConclusionAnalysis of oxygen saturation signal routinely collected in the NICU, may have extensive applications in inferring subtle changes to cardiorespiratory dynamics under various conditions as well as in informing clinical decisions about infant care.</p

Effect of coupling dispersion on the phase response curve (PRC) of the network.

<p>Shown are PRCs with coupling dispersions (<b>A</b>), (<b>B</b>), and (<b>C</b>). Although the network shows relatively larger phase advances and delays with increased coupling dispersion, the area under the phase delay zones is greater than that under the advance zones. The PRCs were similar for all the values of .</p

Effect of coupling dispersion on the critical <i>p</i>.

<p>Shown are the cases for the 22-h (<b>A</b>) and 26-h (<b>B</b>) T cycles.</p

Effect of coupling dispersion on the amplitude of the mean fields of VL and DM.

<p>The case for the 22-h T cycle is shown for VL (<b>A</b>) and DM (<b>B</b>), and the case for the 26-h T cycle is shown for VL (<b>C</b>) and DM (<b>D</b>).</p

Effect of coupling dispersion on the period of the mean fields of VL and DM in the <i>p</i>−<i>K_f</i>

<p><b>plane.</b> The case for the 22-h T cycle is shown for VL (<b>A</b>) and DM (<b>B</b>) with and for VL (<b>C</b>) and DM (<b>D</b>) with . The corresponding case for the 26-h T cycle is represented in (<b>E</b>) - (<b>H</b>).</p

Effect of coupling dispersion on the order parameter of the network.

<p>The case for the 22-h T cycle is shown with coupling dispersion (<b>A</b>) and (<b>B</b>), and the case for the 26-h T cycle is shown with coupling dispersion (<b>C</b>) and (<b>D</b>).</p

Mean field oscillations of VL and DM during a 22-h T cycle.

<p>(<b>A</b>) VL follows the T cycle, whereas DM free runs for the parameters and . (<b>B</b>) Both VL and DM follow the T cycle for the parameters and . The dispersion of the coupling strengths, η, is set to zero in both (<b>A</b>) and (<b>B</b>). The grey bar indicates the dark phase, and the white bar the light phase, of the T cycle.</p

Effect of coupling dispersion on the ratio of the area of the delay zone to the advance zone.

<p>The ratio increases with increasing coupling dispersion.</p

Period of the mean fields of VL and DM in the <i>p</i>−<i>K_f</i> plane.

<p>The case for the 22-h T cycle is shown for VL (<b>A</b>) and DM (<b>B</b>), and the case for the 26-h T cycle is shown for VL (<b>C</b>) and DM (<b>D</b>). The coupling strengths are identical for all the oscillators (i.e., η = 0). Entrainment of the sub-network to the 22-h cycle is represented by the yellow region, and entrainment of the sub-network to the 26-h cycle is represented by the blue region.</p