Deformation of face-centered cubic polycrystal and stress tensor components in grains

The transmission electron microscopy (TEM) has been used to indicate the contribution of stress tensorcomponents to internal stresses in deformed polycrystalline austenitic steel. TEM images of steel deformation demonstrate bend extinction contours the parameters of which allow detecting the stress tensor components (bending and torsional stresses of a crystal lattice). The diagrams are constructed for the contribution of stress tensor components to internal stresses in grains having different types of bending. The regularities are obtained for the stress distribution due to bending-torsion of a crystal latticein the deformed face centered cubic crystal system. The experiment shows that the contribution of bending and torsion stress components to the internal stresses is different during the increase of deformation. The torsion stress component always grows with the increase of deformation, while the bending stress component either grows or lowers. The growth in the torsion stress component is typical for grains with compound bending

Comparing alcohol consumption in central and eastern Europe to other European countries

Aims: To give an overview of the volume of alcohol consumption, beverage preference, and patterns of drinking among adults (people 15 years and older) in central and eastern Europe (Bulgaria, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia, and Slovenia) and to compare it to southern and western Europe, Russia and Ukraine. Methods: Secondary data analysis. Consumption and preferred beverage type data for the year 2002 were taken from the WHO Global Status Report on Alcohol and the WHO Global Alcohol Database. Results: Average consumption in central and eastern Europe is high with a relatively large proportion of unrecorded consumption ranging from one litre in Czech Republic and Estonia to 10.5 l in Ukraine. The proportion of heavy alcohol consumption (more than 40 g of pure alcohol per day) among men was the lowest in Bulgaria (25.8%) and the highest in Czech Republic (59.4%). Among women, the lowest proportion of heavy alcohol consumption was registered in Estonia (4.0%) and the highest in Hungary (16.0%). Patterns of drinking are detrimental with a high proportion of binge drinking, especially in the group of countries traditionally drinking vodka. In most countries, beer is now the most prevalent alcoholic beverage. Conclusions: Other studies suggest that the population drinking levels found in central and eastern Europe are linked with higher levels of detrimental health outcomes. Known effective and cost-effective programs to reduce levels of risky drinking should, therefore, be implemented, which may, in turn, lead to a reduction of alcohol-attributable burden of diseas

Canadian Children and Youth in Care: The Cost of Fetal Alcohol Spectrum Disorder

BACKGROUND: A high prevalence of prenatal alcohol exposure has been reported among children in care and thus, the risk of fetal alcohol spectrum disorder (FASD) in this population is high. OBJECTIVE: The purpose of the current study was to estimate the number of children (0–18 years) in care with FASD and to determine the associated cost by age group, gender, and province/territory in Canada in 2011. METHODS: The prevalence of children in care by province/territory was obtained from the Canadian Child Welfare Research Portal, and the number of children in care with FASD for each province/territory was estimated from available epidemiological studies. In order to calculate the total cost per province/territory, the cost per individual per day, by age group, was applied to the respective number of children in care with FASD. RESULTS: The estimated number of children in care with FASD ranged from 2,225 to 7,620, with an annual cost of care ranging from $57.9 to$198.3 million Canadian dollars (CND). The highest overall cost ($29.5 to$101.1 million CND) was for 11–15 year-olds. CONCLUSION: The study findings can be used to demonstrate the substantial economic burden that FASD places on the child welfare system. Attention towards the needs of this population and prevention efforts to reduce FASD incidence in Canada, and other countries are urgently needed

Estimation of national, regional, and global prevalence of alcohol use during pregnancy and fetal alcohol syndrome: a systematic review and meta-analysis

Background Alcohol use during pregnancy is the direct cause of fetal alcohol syndrome (FAS). We aimed to estimate the prevalence of alcohol use during pregnancy and FAS in the general population and, by linking these two indicators, estimate the number of pregnant women that consumed alcohol during pregnancy per one case of FAS. Methods We began by doing two independent comprehensive systematic literature searches using multiple electronic databases for original quantitative studies that reported the prevalence in the general population of the respective country of alcohol use during pregnancy published from Jan 1, 1984, to June 30, 2014, or the prevalence of FAS published from Nov 1, 1973, to June 30, 2015, in a peer-reviewed journal or scholarly report. Each study on the prevalence of alcohol use during pregnancy was critically appraised using a checklist for observational studies, and each study on the prevalence of FAS was critically appraised by use of a method specifi cally designed for systematic reviews addressing questions of prevalence. Studies on the prevalence of alcohol use during pregnancy and/or FAS were omitted if they used a sample population not generalisable to the general population of the respective country, reported a pooled estimate by combining several studies, or were published in iteration. Studies that excluded abstainers were also omitted for the prevalence of alcohol use during pregnancy. We then did country-specifi c randomeff ects meta-analyses to estimate the pooled prevalence of these indicators. For countries with one or no empirical studies, we predicted prevalence of alcohol use during pregnancy using fractional response regression modelling and prevalence of FAS using a quotient of the average number of women who consumed alcohol during pregnancy per one case of FAS. We used Monte Carlo simulations to derive confi dence intervals for the country-specifi c point estimates of the prevalence of FAS. We estimated WHO regional and global averages of the prevalence of alcohol use during pregnancy and FAS, weighted by the number of livebirths per country. The review protocols for the prevalence of alcohol use during pregnancy (CRD42016033835) and FAS (CRD42016033837) are available on PROSPERO. Findings Of 23 470 studies identifi ed for the prevalence of alcohol use, 328 studies were retained for systematic review and meta-analysis; the search strategy for the prevalence of FAS yielded 11 110 studies, of which 62 were used in our analysis. The global prevalence of alcohol use during pregnancy was estimated to be 9·8% (95% CI 8·9–11·1) and the estimated prevalence of FAS in the general population was 14·6 per 10 000 people (95% CI 9·4–23·3). We also estimated that one in every 67 women who consumed alcohol during pregnancy would deliver a child with FAS, which translates to about 119 000 children born with FAS in the world every year. Interpretation Alcohol use during pregnancy is common in many countries and as such, FAS is a relatively prevalent alcohol-related birth defect. More eff ective prevention strategies targeting alcohol use during pregnancy and surveillance of FAS are urgently needed

Value formation of innovative product : a way to commercialization

Purpose: The issues of studying the value formation process of an innovative product, from the idea to the prototype to the commercialization of the output from the production line, depending on the type of innovations, are the aims of this article. Design/Methodology/Approach: The conceptual framework of "value" and "innovations" is explored and the theoretical basis of the value approach is revealed at the beginning of the article. The definition of an innovative product is given and the development process and the mechanism of its value formation at each development phase are revealed. Findings: The value-added elements are specified, from the idea generation to the commercialization of the innovative product. The expenses for the calculation items and the development phases of the innovative product are estimated. Practical Implications: Categories of the innovation-based economy development, as "innovation", "innovative product", and "value" are not sufficiently studied. Intensive discussions are taking place in the scientific community regarding what an innovative product is and how its value is formed. A specific result of intellectual activity, at the initial stage of its formation represents an idea that is difficult to be estimated. Originality/Value: The problematics for further research of value formation of innovative products depending on their specific nature is put.The article was prepared in the course of carrying out research work within the framework of the project part of the state task in the field of scientific activity in accordance with the task No. 26.2758.2017 / PCh (26.2758.2017 / 4.6) for 2017-2019 on the topic "System for the formation and distribution analysis of the value of innovative products based on the infrastructure concept".peer-reviewe

Noodynamics - an Integrated Part of Healthy Personality`s Nature

The meaning of life and the pursuit of development excite every healthy person. In antiquity, Aristotle states that the ultimate goal of human development is to achieve eudaimonia (happiness). One of the aspects of eudaimonia is health and storing it for a long time has been associated with the theory of homeostasis. Researchers in the new time challenge the idea of homeostasis with another theory, i.e. of noodynamics. The aim of this study is to explore at theoretical and empirical level the importance of the meaning of life and the pursuit of self-actualization in the context of a healthy personality. We studied classical and modern scientific theories of healthy personality. Respondents were 100 people in Varna region in the stage of youth. Alternative, graphic and comparative analyses were accomplished. Our study shows that the availability of purpose that gives meaning and direction in life is extremely important for 80% of the participants. Some 60% believe that they are aware of their personal and professional development over the next 5 years. Some 80% do not accept their life-style and strongly desire certain change. Between 24% and 80% of the participants experienced emptiness in their life as a manifestation of an existential vacuum. For a healthy personality it is not so important to maintain homeostasis, as much as noodynamics related to the realization of personal purposes and goals. The existential vacuum is the result of frustrated development needs and a negative health indicator