Supplementary Figure S5 from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Figure S5. C086 treatment does not affect the engraftment of normal bone marrow cells in NOD-SCID mice.</p

Supplementary Figure S3 from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Figure S3. Effects of C086 on cell cycle progression.</p

Supplementary Figure S4 from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Figure S4. C086 potently inhibits the growth of human leukemia progenitor/stem cells.</p

Supplementary Figure S1 from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Figure S1. C086 induces apoptosis in imatinib-sensitive and -resistant CML cells.</p

Supplementary Figure S2 from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Figure S2. C086 triggers the mitochondrial pathway of apoptosis in CML cells.</p

Supplementary Figure S6 from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Figure S6. The scheme of origins of LSCs and the effects of C086 on LSCs via eradicate leukemia cells at different mature state.</p

Supplementary Methods and Materials, Figure Legend from Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Supplementary Methods and Materials, Figure Legend</p