88 research outputs found

    As artes visuais no processo de aprendizagem infantil

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    O relat√≥rio de investiga√ß√£o intitulado ‚ÄúAs Artes Visuais no Processo de Aprendizagem Infantil‚ÄĚ tem como principal finalidade perceber o modo como as Artes Visuais s√£o trabalhadas, pelos educadores, com crian√ßas em Educa√ß√£o Pr√©-Escolar. Sendo a crian√ßa um ser curioso, criativo e capaz de se relacionar de diferentes formas com o mundo que a rodeia, procuramos tentar perceber ao longo do relat√≥rio, tanto com fundamenta√ß√£o te√≥rica mas tamb√©m atrav√©s da parte metodol√≥gica, as in√ļmeras potencialidades adquiridas pelas crian√ßas, com o contacto com a arte desde cedo, analisando a forma como os educadores as incluem nas suas atividades. Como meio de explorar esta tem√°tica foram delineadas duas perguntas de partida, sendo estas ‚ÄúDe que modo √© que as artes visuais podem contribuir para o processo de aprendizagem infantil? ‚Äúe ‚ÄúDe que forma √© que as artes visuais podem estimular a criatividade nas crian√ßas?‚ÄĚ, para as quais se definiram objetivos passando estes por: perceber de que modo √© que as Artes Visuais podem contribuir para o processo de aprendizagem infantil; entender quais as estrat√©gias e m√©todos que se poder√£o utilizar ao n√≠vel das artes visuais de modo a cativar o interesse das crian√ßas; compreender a import√Ęncia do papel do educador nas artes visuais e analisar de que forma √© que as Artes Visuais s√£o trabalhadas na Educa√ß√£o Pr√©-Escolar. Assim sendo, a investiga√ß√£o do estudo decorre atrav√©s do car√°cter qualitativo, tendo por base as entrevistas como t√©cnica de recolha de dados, tendo sido estas realizadas junto de educadores de inf√Ęncia de diversas institui√ß√Ķes em diferentes pontos do pa√≠s (Portugal). A aplica√ß√£o e an√°lise das entrevistas teve como principal objetivo compreender, principalmente, a vis√£o dos educadores perante as Artes Visuais atrav√©s da partilha das suas pr√°ticas no dia a dia no jardim de inf√Ęncia. Em suma, e perante a an√°lise da investiga√ß√£o, os dados revelaram que de facto as Artes Visuais s√£o valorizadas pelos educadores de inf√Ęncia, tendo estes o cuidado de as incluir junto das crian√ßas no seu quotidiano, organizando o ambiente educativo para que possam explorar os diversos materiais presentes e indo tamb√©m desta forma, de um modo mais l√ļdico, adquirindo certas compet√™ncias que contribuem para o seu desenvolvimento. Palavras-chave: Artes Visuais; Educa√ß√£o Pr√©-Escolar; Compet√™ncias; Aprendizage

    Analytical assessment and nutritional adequacy of school lunches in Sintra’s public primary schools

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    © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).School meals present several cost benefits overtime at the short, medium, and long term for individuals and society. This cross-sectional study aims to analyse the nutritional composition and evaluate the adequacy of school lunches. One hundred and fifty-eight samples were collected and analysed from 10 primary schools in Sintra's municipality, served during one week. On average, energy (27.7% daily energetic requirements) and carbohydrate (48.1%) contents did not reach the reference values, and the content of protein (19.5%) exceeded the reference value (p < 0.05). The mean total fat (28.8%) and saturated fatty acids (5.4%) content complied with the recommendations. The mean salt (1.7 g) and dietary fibre (8.3 g) content exceeded the reference value but did not differ significantly from the recommendations. Addressing school canteens is crucial, not only in a nutritional approach, but also as an opportunity to achieve healthier, sustainable, and accessible food systems, aligned with the Sustainable Development Goals 2030. We highlighted the importance of evaluating evidence-based practices and disseminated practice-based evidence regarding the adequacy of school lunches.info:eu-repo/semantics/publishedVersio

    Sintra Grows Healthy: development and implementation of a food literacy curriculum for primary schools

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    Project Calouste Gulbenkian Foundation no. 231980 (Gulbenkian Academies of Knowledge).Objective: Describe the process of development and implementation of Health at the Table - a food literacy curriculum for primary school-aged children. Design: Through a community-based research process, Health at the table development and implementation took place in four stages: exploratory study, production, implementation, and monitoring. Setting: Primary schools of Sintra's municipality, Portugal. Participants: Children (6 to 10 years), teachers, school staff, and children's legal guardians of three primary schools during the pilot project and eight primary schools in the second year. Results: During the needs assessment phase, 99.1% (n=341) of the children's legal guardians, 100% (n=34) of the teachers, and 100% (n=19) of the school staff considered that the school plays an important or very important role in children's food literacy (stage 1). During the pilot project, a manual with 60 session plans was developed (stage 2). In the second year, Health at the Table was implemented by 72 trained teachers during one school year (stage 3). Most of the teachers agreed that the curriculum was appropriate (69.2%) and that children developed health, wellness/well-being, and environmental skills (83.1%). Most of the children said they had learned about healthy eating (86.3%) and claimed to eat healthier since the Health at the Table implementation (58.9%) (stage 4). Conclusions: Health at the Table is a food literacy curriculum that can be reproduced in similar contexts in a sustainable way. The need to combine educational strategies with a healthy school food environment is reinforced to increase the effectiveness in tackling childhood obesity.info:eu-repo/semantics/publishedVersio

    Enrichment of IFN- producing cells in different murine adipose tissue depots upon infection with an apicomplexan parasite.

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    Here we report that lean mice infected with the intracellular parasite Neospora caninum show a fast but sustained increase in the frequency of IFN-ő≥-producing cells noticeable in distinct adipose tissue depots. Moreover, IFN-ő≥-mediated immune memory could be evoked in vitro in parasite antigen-stimulated adipose tissue stromal vascular fraction cells collected from mice infected one year before. Innate or innate-like cells such as NK, NK T and TCRő≥őī(+) cells, but also CD4(+) and CD8(+) TCRő≤(+) lymphocytes contributed to the IFN-ő≥ production observed since day one of infection. This early cytokine production was largely abrogated in IL-12/IL23 p40-deficient mice. Moreover, production of IFN-ő≥ by stromal vascular fraction cells isolated from these mice was markedly lower than that of wild-type counterparts upon stimulation with parasite antigen. In wild-type mice the increased IFN-ő≥ production was concomitant with up-regulated expression of genes encoding interferon-inducible GTPases and nitric oxide synthase, which are important effector molecules in controlling intracellular parasite growth. This increased gene expression was markedly impaired in the p40-deficient mice. Overall, these results show that NK cells but also diverse T cell populations mediate a prompt and widespread production of IFN-ő≥ in the adipose tissue of N. caninum infected mice

    Protease inhibitor activity of plant natural products as leishmanicine agents / Atividade de inibidores de proteases de produtos naturais contra agentes leishmanicidas

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    Objective: Investigate plant natural products with inhibitory activity of Leishmania proteases, because the inhibition of certain proteases induce the parasite death. Methods: Descriptive/exploratory study, integrative review type. The search was performed in the following databases: Scientific Electronic Library OnLine (SciELO), Medical Literature Analysis and Retrieval System Online (MEDLINE), Latin American and Caribbean Health Science Literature Database (LILACS) and PUBMED. The descriptors were used in combination, from the consultation in the Descriptors in Health Sciences (DECS) and Medical Subject Headings (MeSH), were: (Leishmania) AND (Protease Inhibitor) AND (Vegetable extracts); (Leishmania) AND (Protease Inhibitor) AND (Plant Extracts). Studies in English and Portuguese, published between 2000 and 2020, were included. Finally, the articles were categorized and analyzed. Results and discussion: This review included eight studies, published between 2000 and 2020. There were two publications in 2014, 2017 and 2019, in relation to the language, all eight studies were published in English. Five studies were carried out in India, two in Brazil and one in Iran. Seven of these were found in PUBMED database and one from MEDLINE, all were experimental, comprising in vitro research or using mice as animal models. Conclusions: It was noted that they use similar protocols for the isolation of protease inhibitor from plant species (affinity chromatography) and proteases from Leishmania sp. (cell lysis and protein precipitation and affinity chromatography). However, research involving Leishmania protease inhibitors are still scarce, requiring further studies on the subject, since the understanding of the functioning of these molecules has much to contribute to the development of new therapeutic targets

    Patient-physician discordance in assessment of adherence to inhaled controller medication: a cross-sectional analysis of two cohorts

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    We aimed to compare patient's and physician's ratings of inhaled medication adherence and to identify predictors of patient-physician discordance.(SFRH/BPD/115169/2016) funded by Funda√ß√£o para a Ci√™ncia e Tecnologia (FCT); ERDF (European Regional Development Fund) through the operations: POCI-01-0145-FEDER-029130 ('mINSPIRERS‚ÄĒmHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases‚ÄĒgeneralisation and evaluation of gamification, peer support and advanced image processing technologies') cofunded by the COMPETE2020 (Programa Operacional Competitividade e Internacionaliza√ß√£o), Portugal 2020 and by Portuguese Funds through FCT (Funda√ß√£o para a Ci√™ncia e a Tecnologia).info:eu-repo/semantics/publishedVersio

    Morphological and Postural changes in the foot during pregnancy and puerperium : a longitudinal study

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    The aim of this study is to observe the morphological and postural changes to the foot that take place during pregnancy and the puerperium. Method: In this descriptive, observational, longitudinal study, we analysed 23 pregnant women, with particular attention to morphological and postural aspects of the foot, at three time points during and after pregnancy: in weeks 9-13 of gestation, weeks 32-35 of gestation and weeks 4-6 after delivery. The parameters considered were changes in foot length, the Foot Posture Index (FPI) and the Hern√°ndez Corvo Index, which were analysed using a pedigraph and taking into account the Body Mass Index (BMI). The same procedure was conducted in each review. Results: The statistical analyses obtained for each foot did not differ significantly between the three measurement times. A pronator-type footprint was most frequently observed during the third trimester of pregnancy; it was predominantly neutral during the postpartum period. Statistically significant differences between the measurement times were obtained in the right foot for cavus vs. neutral foot type (between the first and third trimesters and also between the first trimester and the puerperium) (in both cases, p < 0.0001). Conclusions: Foot length increases in the third trimester and returns to normal in the puerperium. According to FPI findings, the third trimester of pregnancy is characterised by pronation, while the posture returns to neutrality during the postpartum period. During pregnancy, the plantar arch flattens, and this persists during the puerperium. The incidence of cavus foot increases significantly in the third trimester and in the puerperium

    Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in Portugal

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    Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the highest impact on case numbers and fitted them into a global context, finding evidence that several international sublineages probably emerged or spread early in Portugal. We estimated a 62% infection reporting rate and that 1.3% of the population of men who have sex with men in Portugal were infected. We infer the critical role played by sexual networks and superspreader gatherings, such as sauna attendance, in the dissemination of mpox virus. Overall, our findings highlight genomic epidemiology as a tool for the real-time monitoring and control of mpox epidemics, and can guide future vaccine policy in a highly susceptible population.info:eu-repo/semantics/publishedVersio

    Identification of clusters of asthma control: A preliminary analysis of the inspirers studies

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    This work was funded by ERDF (European Regional Development Fund) through the operations: POCI- -01-0145-FEDER-029130 (‚ÄúmINSPIRERS‚ÄĒmHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases - generalisation and evaluation of gamification, peer support and advanced image processing technologies‚ÄĚ) co-funded by the COMPETE2020 (Programa Operacional Competitividade e Internacionaliza√ß√£o), Portugal 2020 and by Portuguese Funds through FCT (Funda√ß√£o para a Ci√™ncia e a Tecnologia).¬© 2020, Sociedade Portuguesa de Alergologia e Imunologia Clinica. All rights reserved. Aims: To identify distinct asthma control clusters based on Control of Allergic Rhinitis and Asthma Test (CARAT) and to compare patients‚Äô characteristics among these clusters. Methods: Adults and adolescents (‚Č•13 years) with persistent asthma were recruited at 29 Portuguese hospital outpatient clinics, in the context of two observational studies of the INSPIRERS project. Demographic and clinical characteristics, adherence to inhaled medication, beliefs about inhaled medication, anxiety and depression, quality of life, and asthma control (CARAT, >24 good control) were collected. Hierarchical cluster analysis was performed using CARAT total score (CARAT-T). Results: 410 patients (68% adults), with a median (percentile 25‚Äďpercentile 75) age of 28 (16-46) years, were analysed. Three clusters were identified [mean CARAT-T (min-max)]: cluster 1 [27(24-30)], cluster 2 [19(14-23)] and cluster 3 [10(2-13)]. Patients in cluster 1 (34%) were characterised by better asthma control, better quality of life, higher inhaler adherence and use of a single inhaler. Patients in clusters 2 (50%) and 3 (16%) had uncontrolled asthma, lower inhaler adherence, more symptoms of anxiety and depression and more than half had at least one exacerbation in the previous year. Further-more, patients in cluster 3 were predominantly female, had more unscheduled medical visits and more anxiety symp-toms, perceived a higher necessity of their prescribed inhalers but also higher levels of concern about taking these inhalers. There were no differences in age, body mass index, lung function, smoking status, hospital admissions or specialist physician follow-up time among the three clusters. Conclusion: An unsupervised method based on CARAT--T, identified 3 clusters of patients with distinct, clinically meaningful characteristics. The cluster with better asthma control had a cut-off similar to the established in the validation study of CARAT and an additional cut-off seems to distinguish more severe disease. Further research is necessary to validate the asthma control clusters identified.publishersversionpublishe

    SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal

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    Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration with more than 50 laboratories distributed nationwide. Methods By applying recent phylodynamic models that allow integration of individual-based travel history, we reconstructed and characterized the spatio-temporal dynamics of SARSCoV-2 introductions and early dissemination in Portugal. Results We detected at least 277 independent SARS-CoV-2 introductions, mostly from European countries (namely the United Kingdom, Spain, France, Italy, and Switzerland), which were consistent with the countries with the highest connectivity with Portugal. Although most introductions were estimated to have occurred during early March 2020, it is likely that SARS-CoV-2 was silently circulating in Portugal throughout February, before the first cases were confirmed. Conclusions Here we conclude that the earlier implementation of measures could have minimized the number of introductions and subsequent virus expansion in Portugal. This study lays the foundation for genomic epidemiology of SARS-CoV-2 in Portugal, and highlights the need for systematic and geographically-representative genomic surveillance.We gratefully acknowledge to Sara Hill and Nuno Faria (University of Oxford) and Joshua Quick and Nick Loman (University of Birmingham) for kindly providing us with the initial sets of Artic Network primers for NGS; Rafael Mamede (MRamirez team, IMM, Lisbon) for developing and sharing a bioinformatics script for sequence curation (https://github.com/rfm-targa/BioinfUtils); Philippe Lemey (KU Leuven) for providing guidance on the implementation of the phylodynamic models; Joshua L. Cherry (National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health) for providing guidance with the subsampling strategies; and all authors, originating and submitting laboratories who have contributed genome data on GISAID (https://www.gisaid.org/) on which part of this research is based. The opinions expressed in this article are those of the authors and do not reflect the view of the National Institutes of Health, the Department of Health and Human Services, or the United States government. This study is co-funded by Fundação para a Ciência e Tecnologia and Agência de Investigação Clínica e Inovação Biomédica (234_596874175) on behalf of the Research 4 COVID-19 call. Some infrastructural resources used in this study come from the GenomePT project (POCI-01-0145-FEDER-022184), supported by COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation (POCI), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal Regional Operational Programme (CRESC Algarve2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), and by Fundação para a Ciência e a Tecnologia (FCT).info:eu-repo/semantics/publishedVersio
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