Features and interventions of cardiac arrest events by neurological status at hospital discharge.

Features and interventions of cardiac arrest events by neurological status at hospital discharge.</p

Multivariate survival analysis for termination of cardiopulmonary resuscitation efforts using a Cox’s proportional hazards model.

Multivariate survival analysis for termination of cardiopulmonary resuscitation efforts using a Cox’s proportional hazards model.</p

Outcomes of Adult In-Hospital Cardiac Arrest Treated with Targeted Temperature Management: A Retrospective Cohort Study

<div><p>Aim</p><p>Targeted temperature management (TTM) for in-hospital cardiac arrest (IHCA) is given different recommendation levels within international resuscitation guidelines. We aimed to identify whether TTM would be associated with favourable outcomes following IHCA and to determine which factors would influence the decision to implement TTM.</p><p>Methods</p><p>We conducted a retrospective observational study in a single medical centre. We included adult patients suffering IHCA between 2006 and 2014. We used multivariable logistic regression analysis to evaluate associations between independent variables and outcomes.</p><p>Results</p><p>We included a total of 678 patients in our analysis; only 22 (3.2%) patients received TTM. Most (81.1%) patients met at least one exclusion criteria for TTM. In all, 144 (21.2%) patients survived to hospital discharge; among them, 60 (8.8%) patients displayed favourable neurological status at discharge. TTM use was significantly associated with favourable neurological outcome (OR: 3.74, 95% confidence interval [CI]: 1.19–11.00; <i>p</i>-value = 0.02), but it was not associated with survival (OR: 1.41, 95% CI: 0.54–3.66; <i>p</i>-value = 0.48). Arrest in the emergency department was positively associated with TTM use (OR: 22.48, 95% CI: 8.40–67.64; <i>p</i> value < 0.001) and having vasopressors in place at the time of arrest was inversely associated with TTM use (OR: 0.08, 95% CI: 0.004–0.42; <i>p</i>-value = 0.02).</p><p>Conclusion</p><p>TTM might be associated with favourable neurological outcome of IHCA patients, irrespective of arrest rhythms. The prevalence of proposed exclusion criteria for TTM was high among IHCA patients, but these factors did not influence the use of TTM in clinical practice or neurological outcomes after IHCA.</p></div

Additional file 3: Table S2. of Monitoring of serum lactate level during cardiopulmonary resuscitation in adult in-hospital cardiac arrest

Baseline characteristics of study patients stratified by lactate level. (DOCX 17 kb

Validation of the Cardiac Arrest Survival Postresuscitation In-hospital (CASPRI) score in an East Asian population

BackgroundThe Cardiac Arrest Survival Postresuscitation In-hospital (CASPRI) score is a useful tool for predicting neurological outcome following in-hospital cardiac arrest (IHCA), and was derived from a cohort selected from the Get With The Guidelines-Resuscitation registry between 2000 and 2009 in the United States. In an East Asian population, we aimed to identify the factors associated with outcomes of resuscitated IHCA patients and assess the validity of the CASPRI score.MethodsA retrospective study was conducted in a single centre in Taiwan. Patients with IHCA between 2006 and 2014 were screened.ResultsAmong the 796 included patients, 94 (11.8%) patients achieved neurologically intact survival. Multivariable logistic regression analyses identified factors significantly associated with neurological outcome. Six of these factors were also components of the CASPRI score, including duration of resuscitation, neurological status before IHCA, malignant disease, initial arrest rhythms, renal insufficiency and age. In univariate logistic regression analysis, the CASPRI score was significantly associated with neurological outcome (odds ratio [OR]: 0.83, 95% confidence interval [CI]: 0.80–0.87); the area under the receiver operating characteristics curve was 0.79 (95% CI: 0.74–0.84).ConclusionIn this retrospective study conducted in a single centre at Taiwan, we identified the common prognosticators of IHCA shared by both East Asian and Western societies. As a composite prognosticator, CASPRI score predicts outcomes with excellent accuracy among successfully resuscitated IHCA patients in an East Asian population. This tool allows accurate IHCA prognostication in an East Asian population.</div

Baseline characteristics of study patients by neurological status at hospital discharge.

Baseline characteristics of study patients by neurological status at hospital discharge.</p

MOESM2 of Associations between blood glucose level and outcomes of adult in-hospital cardiac arrest: a retrospective cohort study

Additional file 2: Table S2. Baseline characteristics of study patients stratified by the presence of measurement of blood glucose level after sustained return of spontaneous circulation

Additional file 2: Figure S1. of Monitoring of serum lactate level during cardiopulmonary resuscitation in adult in-hospital cardiac arrest

Generalized additive model plot for non-parametric modelling of the effect of serum lactate level on the logit of probability for survival to hospital discharge. (TIFF 23 kb

Features, interventions, and outcomes of cardiac arrest events stratified by the presence of family members at initiation of cardiopulmonary resuscitation efforts.

Features, interventions, and outcomes of cardiac arrest events stratified by the presence of family members at initiation of cardiopulmonary resuscitation efforts.</p

Baseline characteristics of study patients stratified by the presence of family members at initiation of cardiopulmonary resuscitation efforts.

Baseline characteristics of study patients stratified by the presence of family members at initiation of cardiopulmonary resuscitation efforts.</p