1_Data_integration

R Script to load input files and collate into a single matched data frame containing fitness, growth rate, and genetic and biolog distance dat

3_PLSregression_&_correlations

Script to perform ANOVA testing for mutation effect variation over different recipient strains and to perform partial least squares (PLS) regression and plot contribution of independent variables to each componen

fitness_estimates

Fitness estimates of engineered strain

biolog

Biolog profiles of engineered strain

2_mutation_effect_ANOVA

R Script to perform ANOVA to: (i) examine variation in effect of each mutations over strains, (ii) examine variation in average effect of mutations per strain, and (iii) determine average effect of each mutatio

2a_Recipient strains on Broad phylo

R Script to identify engineered strains in context of broader E. coli phylogen