689 research outputs found

    Modeling Siberian ibex (Capra sibirica) occupancy in Ikh Nart Nature Reserve, Mongolia

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    As the world becomes increasingly populated, humans continue to modify habitats to suit their needs. Mongolia is one of many Asian countries currently undergoing human-induced landscape change, namely in the form of increased grazing pressure on the land by domesticated animals. There is uncertainty as to how wildlife will be impacted by this change. The Siberian ibex (Capra sibirica) is an ungulate classified as IUCN Near Threatened in Mongolia and an important species for tourism. I developed an occupancy model for the species based on radio- telemetry locations (n = 920) collected in Ikh Nart Nature Reserve, then estimated the effect of habitat reductions as expected under increasing levels of grazing. I developed 13 candidate models that include combinations of habitat and human variables, and used model selection techniques to evaluate the best-supported model in the set. The model with the most support indicated that rocky outcrop, open plain, and their interaction best described ibex occupancy. Average occupancy was 5.7% across the northern Ikh Nart landscape, 7.4% within the borders of the reserve, and 17.4% within the reserve’s core protected area. Simulations showed that in the absence of open plain habitat, average occupancy declined to 1.9%, 2.1%, and 5.0% respectively in these areas. The results provide a description of how landscape factors shape the distribution of the species. Because livestock grazing is concentrated in open plain habitats, these results may be used to inform decision-making about ibex conservation in the region

    Developing Online Learning Materials for Higher Education: An Overview of Current Issues

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    The changing roles and challenges for higher education and the increased productivity required of faculty are driving forces for the development of more diverse and efficient teaching methods. Educational trends are toward more learner-centered materials. In response to these trends, colleges and universities are now offering courses at a distance and in forms other than traditional delivery. Online courseware materials may be a viable means of fulfilling these numerous requirements but are very resource-intensive to develop. Multiple approaches to developing online learning have been tried, with limited success. The primary approach has been for faculty to enter their own course materials into the computer. To maximize university resources, the most effective approach for developing online learning materials must be determined and institutionalized. While faculty are the most logical persons to provide course content and design, faculty should not be expected to complete the technical tasks associated with developing online learning materials

    An x-ray probe of laser-aligned molecules

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    We demonstrate a hard x-ray probe of laser-aligned small molecules. To align small molecules with optical lasers, high intensities at nonresonant wavelengths are necessary. We use 95 ps pulses focused to 40 mum from an 800 nm Ti:sapphire laser at a peak intensity of 10^12 W/cm^2 to create an ensemble of aligned bromotrifluoromethane (CF3Br) molecules. Linearly polarized, 120 ps x-ray pulses, focused to 10 mum, tuned to the Br 1s --> sigma* pre-edge resonance at 13.476 keV, probe the ensemble of laser-aligned molecules. The demonstrated methodology has a variety of applications and can enable ultrafast imaging of laser-controlled molecular motions with Angstrom-level resolution.Comment: 4 pages, 4 figures, RevTeX4, corrected typo

    Rape and Mental Health Outcomes Among Women: Examining the Moderating Effects of “Healthy” Fear Levels

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    This study examined the mediating and moderating impact of fear of victimization on the relationships between forcible and vicarious rape on depression and PTSD among college women. Forcible and vicarious rape positively affected PTSD and depression symptomology, but fear did not mediate these relationships. Fear moderated the impact of forcible rape on PTSD, but was not a moderator for depression. Findings suggest that there may be “healthy” levels of fear in the aftermath of victimization where having too little fear may leave women unnecessarily vulnerable to victimization, while having too much fear may lead to social isolation and withdrawal

    Barriers to Adoption of a Child-Abuse Clinical Decision Support System in Emergency Departments

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    Introduction: Child abuse is a leading cause of morbidity and mortality in children. The rate of missed child abuse in general emergency departments (ED), where 85% of children are evaluated, is higher than in pediatric EDs. We sought to evaluate the impact of an electronic health record (EHR)-embedded child-abuse clinical decision support system (CA-CDSS) in the identification and evaluation of child maltreatment in a network of EDs three years after implementation. Methods: We anonymously surveyed all 196 ED attending physicians and advanced practice practitioners (APP) in the University of Pittsburgh Medical Center network. The survey evaluated practitioner awareness of, attitudes toward, and changes in clinical practice prompted by the CA-CDSS. We also assessed practitioner recognition and evaluation of sentinel injuries. Results: Of the 71 practitioners (36%) who responded to the survey, 75% felt the tool raised child abuse awareness, and 72% had a face-to-face discussion with the child’s nurse after receiving a CA-CDSS alert. Among APPs, 72% consulted with the attending physician after receiving an alert. Many practitioners were unaware of at least one function of the CA-CDSS; 38% did not know who completed the child abuse screen (CAS); 54% were unaware that they could view the results of the CAS in the EHR, and 69% did not recognize the clinical decision support dashboard icon. Slightly over 20% of respondents felt that the CA-CDSS limited autonomy; and 4.5% disagreed with the recommendations in the physical abuse order set, which reflects American Academy of Pediatrics (AAP) guidelines. Greater than 90% of respondents correctly identified an intraoral injury and torso bruise in an infant as sentinel injuries requiring an evaluation for abuse. Conclusion: A child-abuse clinical decision support system embedded in the electronic health record was associated with communication among practitioners and was overall perceived as improving child abuse awareness in our system. Practitioners correctly recognized injuries concerning for abuse. Barriers to improving identification and evaluation of abuse include gaps in knowledge about the CA-CDSS and the presence of practitioners who disagree with the AAP recommendations for physical abuse evaluation and/or felt that clinical decision support in general limited their clinical autonomy

    Impacts of Census Differential Privacy for Small-Area Disease Mapping to Monitor Health Inequities

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    The US Census Bureau will implement a new privacy-preserving disclosure avoidance system (DAS), which includes application of differential privacy, on publicly-released 2020 census data. There are concerns that the DAS may bias small-area and demographically-stratified population counts, which play a critical role in public health research, serving as denominators in estimation of disease/mortality rates. Employing three DAS demonstration products, we quantify errors attributable to reliance on DAS-protected denominators in standard small-area disease mapping models for characterizing health inequities. We conduct simulation studies and real data analyses of inequities in premature mortality at the census tract level in Massachusetts and Georgia. Results show that overall patterns of inequity by racialized group and economic deprivation level are not compromised by the DAS. While early versions of DAS induce errors in mortality rate estimation that are larger for Black than non-Hispanic white populations in Massachusetts, this issue is ameliorated in newer DAS versions

    Dual Roles of Fer Kinase Are Required for Proper Hematopoiesis and Vascular Endothelium Organization during Zebrafish Development

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    Fer kinase, a protein involved in the regulation of cell-cell adhesion and proliferation, has been shown to be required during invertebrate development and has been implicated in leukemia, gastric cancer, and liver cancer. However, in vivo roles for Fer during vertebrate development have remained elusive. In this study, we bridge the gap between the invertebrate and vertebrate realms by showing that Fer kinase is required during zebrafish embryogenesis for normal hematopoiesis and vascular organization with distinct kinase dependent and independent functions. In situ hybridization, quantitative PCR and fluorescence activated cell sorting (FACS) analyses revealed an increase in both erythrocyte numbers and gene expression patterns as well as a decrease in the organization of vasculature endothelial cells. Furthermore, rescue experiments have shown that the regulation of hematopoietic proliferation is dependent on Fer kinase activity, while vascular organizing events only require Fer in a kinase-independent manner. Our data suggest a model in which separate kinase dependent and independent functions of Fer act in conjunction with Notch activity in a divergent manner for hematopoietic determination and vascular tissue organization

    LSST Science Book, Version 2.0

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    A survey that can cover the sky in optical bands over wide fields to faint magnitudes with a fast cadence will enable many of the exciting science opportunities of the next decade. The Large Synoptic Survey Telescope (LSST) will have an effective aperture of 6.7 meters and an imaging camera with field of view of 9.6 deg^2, and will be devoted to a ten-year imaging survey over 20,000 deg^2 south of +15 deg. Each pointing will be imaged 2000 times with fifteen second exposures in six broad bands from 0.35 to 1.1 microns, to a total point-source depth of r~27.5. The LSST Science Book describes the basic parameters of the LSST hardware, software, and observing plans. The book discusses educational and outreach opportunities, then goes on to describe a broad range of science that LSST will revolutionize: mapping the inner and outer Solar System, stellar populations in the Milky Way and nearby galaxies, the structure of the Milky Way disk and halo and other objects in the Local Volume, transient and variable objects both at low and high redshift, and the properties of normal and active galaxies at low and high redshift. It then turns to far-field cosmological topics, exploring properties of supernovae to z~1, strong and weak lensing, the large-scale distribution of galaxies and baryon oscillations, and how these different probes may be combined to constrain cosmological models and the physics of dark energy.Comment: 596 pages. Also available at full resolution at http://www.lsst.org/lsst/sciboo
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