3-D surface modelling of the human body and 3-D surface anthropometry

This thesis investigates three-dimensional (3-D) surface modelling of the human body and 3-D surface anthropometry. These are two separate, but closely related, areas. 3-D surface modelling is an essential technology for representing and describing the surface shape of an object on a computer. 3-D surface modelling of the human body has wide applications in engineering design, work space simulation, the clothing industry, medicine, biomechanics and animation. These applications require increasingly realistic surface models of the human body. 3-D surface anthropometry is a new interdisciplinary subject. It is defined in this thesis as the art, science, and technology of acquiring, modelling and interrogating 3-D surface data of the human body. [Continues.

Of Natural Killer cells and Hepatitis C Virus

Natural Killer (NK) cells are important effector cells in Hepatitis C Virus (HCV) infection, a virus that chronically infects around 2.5% of the world population and is a major cause of liver disease and hepatocellular carcinoma. The exact mechanisms, however, through which NK cells are activated in response to HCV remain elusive. Using the well-established HCV replicon cell-culture model we show that after co- culture of HCV replicon-carrying hepatocytes with peripheral blood mononuclear cells (PBMCs), NK cells increase expression of the high-affinity IL-2 receptor chain CD25, proliferate rapidly and produce IFN-gamma. Activation of NK cells was dependent on IL-2, most likely produced by T cells and on cell-cell contact mediated signals from monocytes. Monocytes from replicon-carrying co-cultures showed increased expression of OX40L, a member of the tumor necrosis factor family and concurrently its receptor OX40 was increased on NK cells. Blocking of OX40L in those co-cultures, as well as depletion of CD14+ monocytes abrogated the virus-induced activation and effector functions of NK cells. Together, our data reveals a novel mechanism of monocyte mediated NK cell activation against virus-infected cells involving the OX40/OX40L axis with potential relevance for therapeutic intervention by e.g. agonistic antibodies against OX40, which are already tested in cancer therapy

Assessing slope forest effect on flood process caused by a short-duration storm in a small catchment

Land use has significant impact on the hydrologic and hydraulic processes in a catchment. This work applies a hydrodynamic based numerical model to quantitatively investigate the land use effect on the flood patterns under various rainfall and terrain conditions in an ideal V-shaped catchment and a realistic catchment, indicating the land use could considerably affect the rainfall-flood process and such effect varies with the catchment terrain, land use scenario and the rainfall events. The rainfall-flood process is less sensitive for the side slope than the channel slope. For a channel slope lower than the critical value in this work, the forest located in the middle of the catchment slope could most effectively attenuate the flood peak. When the channel slope is higher than the critical one, forest located in the downstream of the catchment could most significantly mitigate the peak discharge. Moreover, the attenuation effect becomes more obvious as the rainfall becomes heavier. The fragmentation of vegetation does not reduce the flood peak in a more obvious way, compared with the integral vegetation patterns with the same area proportion. The research can help more reasonably guide the land use plan related to flood risk

Visualization 1.avi

Dynamic mapping of the BGC response during OGTT with the capillary resolutio

Visualization 1

FLS-evoked hemodynamic responses of mouse retina in viv

3-D surface modelling of the human body and 3-D surface anthropometry

This thesis investigates three-dimensional (3-D) surface modelling of the human body and 3-D surface anthropometry. These are two separate, but closely related, areas. 3-D surface modelling is an essential technology for representing and describing the surface shape of an object on a computer. 3-D surface modelling of the human body has wide applications in engineering design, work space simulation, the clothing industry, medicine, biomechanics and animation. These applications require increasingly realistic surface models of the human body. 3-D surface anthropometry is a new interdisciplinary subject. It is defined in this thesis as the art, science, and technology of acquiring, modelling and interrogating 3-D surface data of the human body. [Continues.

MOESM1 of Genome-wide characterization of the Rab gene family in Gossypium by comparative analysis

Additional file 1. List of Rab genes in G. raimondii, G. hirsutum, G. barbadense and G. arboreum, respectively

Patient characteristics.

PurposeExcision of intracranial meningioma has been associated with major intraoperative blood loss (IBL). The objective of the study was to identify factors affecting IBL during removal of meningioma.MethodsWe retrospectively studied medical records of 530 adult patients who underwent surgery for intracranial meningioma at Sichuan Provincial People’s Hospital between September 2018 and May 2022. We obtained the following data from each patient’s medical chart: age, sex, height, weight, comorbidities, blood pressure, history of smoking and alcohol, imaging examination findings, pathologic diagnosis, albumin, creatinine, calcium, magnesium, hemoglobin (Hb), hematocrit, platelet count, activated partial thromboplastin time, international normalized ratio, fibrinogen concentration and blood transfusion. Univariate and multivariate analyses were performed to identify risk factors for greater IBL during removal of intracranial meningioma.ResultsA total of 530 patients were included in our study. Univariate analysis revealed that sex (p = 0.004), two-dimensional (2D) tumor area (p p = 0.014), World Health Organization grade (p = 0.015), preoperative albumin level (p = 0.032), preoperative Hb level (p = 0.001) and preoperative platelet count (p = 0.004) were significantly associated with greater IBL. Multivariate analysis revealed that greater 2D tumor area (p p = 0.029) and higher preoperative platelet count (p = 0.03) were independent risk factors for greater IBL in resection of intracranial meningioma.ConclusionLarger tumor size, higher preoperative albumin concentration and higher preoperative platelet count were identified as independent risk factors for greater IBL in resection of intracranial meningioma.</div

Univariate analysis of association between each factor and IBL.

Univariate analysis of association between each factor and IBL.</p

Supplementary Material.docx

Supplement 1</p