Arabian adventures

The United Arab Emirates (UAE) is one of the world’s most rapidly urbanising countries. Despite the recent downturn in the economy, the region continues to undergo rapid development, particularly around Abu Dhabi and Dubai. Consequently the country is host to many major civil engineering projects including the world’s tallest building, artificial offshore islands, new international airports, metro systems and high-speed rail networks

The ethical infrastructure of legal practice in larger law firms: values, policy and behaviour

The article examines the impact of the cultures and organisational structures of large law firms on individual lawyers' ethics. The paper suggests that large law firms in Australia should consciously design and implement 'ethical infrastructures' to both counteract pressures for misbehaviour and positively promote ethical behaviour and discussion. The paper goes on to explain what implementing ethical infrastructures in law firms could and should mean by reference to what Australian law firms are already doing and US innovations in this area. Finally, the paper warns that the 'ethical infrastructure' of a firm should not be seen merely as the formal ethics policies explicitly enunciated by management. Formal and legalistic ethical infrastructures that fail to support or encourage the development of individual lawyers' awareness oftheir own ethical values and ethical judgment in practice will be useless

Seasonal and interannual behaviour of groundwater catchment boundaries in a Chalk aquifer

Groundwater catchment boundaries and their associated groundwater catchment areas are typically assumed to be fixed on a seasonal basis. We investigated whether this was true for a highly permeable carbonate aquifer in England, the Berkshire and Marlborough Downs Chalk aquifer, using both borehole hydrograph data and a physics-based distributed regional groundwater model. Borehole hydrograph data time series were used to construct a monthly interpolated water table surface, from which was then derived a monthly groundwater catchment boundary. Results from field data showed that the mean annual variation in groundwater catchment area was about 20% of the mean groundwater catchment area, but interannual variation can be very large, with the largest estimated catchment size being approximately 80% greater than the smallest. The flow in the river was also dependent on the groundwater catchment area. Model results corroborated those based on field data. These findings have significant implications for issues such as definition of source protection zones, recharge estimates based on water balance calculations and integrated conceptual modelling of surface water and groundwater system

Osmotic and stimulant laxatives for the management of childhood constipation

Background Constipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals to manage constipation in children, there has been a long standing paucity of high quality evidence to support this practice. Objectives We set out to evaluate the efficacy and safety of osmotic and stimulant laxatives used to treat functional childhood constipation. Search methods We searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, and the Cochrane IBD Group Specialized Trials Register from inception to 10 March 2016. There were no language restrictions. We also searched the references of all included studies, personal contacts and drug companies to identify studies. Selection criteria Randomised controlled trials (RCTs) which compared osmotic or stimulant laxatives to placebo or another intervention, with participants aged 0 to 18 years old were considered for inclusion. The primary outcome was frequency of defecation. Secondary endpoints included faecal incontinence, disimpaction, need for additional therapies and adverse events. Data collection and analysis Relevant papers were identified and two authors independently assessed the eligibility of trials, extracted data and assessed methodological quality using the Cochrane risk of bias tool. The primary outcome was frequency of defecation. Secondary endpoints included faecal incontinence, disimpaction, need for additional therapies and adverse events. For continuous outcomes we calculated the mean difference (MD) and 95% confidence interval (CI) using a fixed-effect model. For dichotomous outcomes we calculated the risk ratio (RR) and 95% CI using a fixed-effect model. The Chi2 and I2 statistics were used to assess statistical heterogeneity. A random-effects model was used in situations of unexplained heterogeneity. We assessed the overall quality of the evidence supporting the primary and secondary outcomes using the GRADE criteria. Main results Twenty-five RCTs (2310 participants) were included in the review. Fourteen studies were judged to be at high risk of bias due to lack of blinding, incomplete outcome data and selective reporting. Meta-analysis of two studies (101 patients) comparing polyethylene glycol (PEG) with placebo showed a significantly increased number of stools per week with PEG (MD 2.61 stools per week, 95% CI 1.15 to 4.08). Common adverse events in the placebo-controlled studies included flatulence, abdominal pain, nausea, diarrhoea and headache. Participants receiving high dose PEG (0.7 g/kg) had significantly more stools per week than low dose PEG (0.3 g/kg) participants (1 study, 90 participants, MD 1.30, 95% 0.76 to 1.84). Meta-analysis of 6 studies with 465 participants comparing PEG with lactulose showed a significantly greater number of stools per week with PEG (MD 0.70 , 95% CI 0.10 to 1.31), although follow-up was short. Patients who received PEG were significantly less likely to require additional laxative therapies. Eighteen per cent (27/154) of PEG patients required additional therapies compared to 31% (47/150) of lactulose patients (RR 0.55, 95% CI 0.36 to 0.83). No serious adverse events were reported with either agent. Common adverse events in these studies included diarrhoea, abdominal pain, nausea, vomiting and pruritis ani. Meta-analysis of 3 studies with 211 participants comparing PEG with milk of magnesia showed that the stools per week were significantly greater with PEG (MD 0.69, 95% CI 0.48 to 0.89). However, the magnitude of this difference was quite small and may not be clinically significant. One child was noted to be allergic to PEG, but there were no other serious adverse events reported. One study found a significant difference in stools per week favouring milk of magnesia over lactulose (MD -1.51, 95% CI -2.63 to -0.39, 50 patients), Meta-analysis of 2 studies with 287 patients comparing liquid paraffin (mineral oil) with lactulose revealed a relatively large statistically significant difference in the number of stools per week favouring liquid paraffin (MD 4.94 , 95% CI 4.28 to 5.61). No serious adverse events were reported. Adverse events included abdominal pain, distention and watery stools. No statistically significant differences in the number of stools per week were found between PEG and enemas (1 study, 90 patients, MD 1.00, 95% CI -1.58 to 3.58), dietary fibre mix and lactulose (1 study, 125 patients, P = 0.481), senna and lactulose (1 study, 21 patients, P > 0.05), lactitol and lactulose (1 study, 51 patients, MD -0.80, 95% CI -2.63 to 1.03), hydrolyzed guar gum and lactulose (1 study, 61 patients, MD 1.00, 95% CI -1.80 to 3.80), PEG and flixweed (1 study, 109 patients, MD 0.00, 95% CI -0.33 to 0.33), PEG and dietary fibre (1 study, 83 patients, MD 0.20, 95% CI -0.64 to 1.04), and PEG and liquid paraffin (2 studies, 261 patients, MD 0.35, 95% CI -0.24 to 0.95). Authors' conclusions The pooled analyses suggest that PEG preparations may be superior to placebo, lactulose and milk of magnesia for childhood constipation. GRADE analyses indicated that the overall quality of the evidence for the primary outcome (number of stools per week) was low or very low due to sparse data, inconsistency (heterogeneity), and high risk of bias in the studies in the pooled analyses. Thus, the results of the pooled analyses should be interpreted with caution because of quality and methodological concerns, as well as clinical heterogeneity, and short follow-up. There is also evidence suggesting the efficacy of liquid paraffin (mineral oil). There is no evidence to demonstrate the superiority of lactulose when compared to the other agents studied, although there is a lack of placebo controlled studies. Further research is needed to investigate the long term use of PEG for childhood constipation, as well as the role of liquid paraffin. The optimal dose of PEG also warrants further investigation

Inverse Scattering Transform for the Camassa-Holm equation

An Inverse Scattering Method is developed for the Camassa-Holm equation. As an illustration of our approach the solutions corresponding to the reflectionless potentials are explicitly constructed in terms of the scattering data. The main difference with respect to the standard Inverse Scattering Transform lies in the fact that we have a weighted spectral problem. We therefore have to develop different asymptotic expansions.Comment: 17 pages, LaTe

Spindown of massive rotating stars

Models of rapidly rotating massive stars at low metallicities show significantly different evolution and higher metal yields compared to non-rotating stars. We estimate the spin-down time-scale of rapid rotating non-convective stars supporting an alpha-Omega dynamo. The magnetic dynamo gives rise to mass loss in a magnetically controlled stellar wind and hence stellar spin down owing to loss of angular momentum. The dynamo is maintained by strong horizontal rotation-driven turbulence which dominates over the Parker instability. We calculate the spin-down time-scale and find that it could be relatively short, a small fraction of the main-sequence lifetime. The spin-down time-scale decreases dramatically for higher surface rotations suggesting that rapid rotators may only exhibit such high surface velocities for a short time, only a small fraction of their main-sequence lifetime.Comment: Accepted by MNRA

Definition of input data to assess GHG default emissions from biofuels in EU legislation: Version 1c - July 2017

The Renewable Energy Directive (RED) (2009/28/EC) and the Fuel Quality Directive (FQD) (2009/30/EC), amended in 2015 by Directive (EU) 2015/1513 (so called ‘ILUC Directive’), fix a minimum requirement for greenhouse gas (GHG) savings for biofuels and bioliquids for the period until 2020, and set the rules for calculating the greenhouse impact of biofuels, bioliquids and their fossil fuels comparators. To help economic operators to declare the GHG emission savings of their products, default and typical values for a number of spefic pathways are listed in the annexes of the RED and FQD. The EC Joint Research Center (JRC) is in charge of defining input values to be used for the calculation of default GHG emissions for biofuels, bioliquids, solid and gaseous biomass pathways. An update of the GHG emissions in Annex V has been carried out for the new Proposal of a Directive on the Promotion of the Use of Energy from Renewable Sources (COM(2016)767 - RED-2), for the post-2020 framework. This report describes the assumptions made by the JRC when compiling the new updated data set used to calculate default and typical GHG emissions for the different biofuels pathways as proposed in the new RED-2 document.JRC.C.4-Sustainable Transpor

RELACIÓN ENTRE EL RENDIMIENTO ACADÉMICO DE LOS INGRESANTES Y EL ABANDONO DE LOS ESTUDIOS UNIVERSITARIOS: COMPARACIÓN ENTRE CARRERAS DE INGENIERÍA Y ECONOMICAS

La preocupación por orientar adecuadamente los recursos que se afectan a los programas de apoyo a los estudiantes de primer año de las carreras, nos llevó a trabajar intentando generar un modelo que sea capaz de determinar, anticipadamente, que estudiantes se encontrarían en situación de abandonar sus estudios. En una primera aplicación del modelo, se analizó la correlación entre el rendimiento académico y el abandono para diez cohortes de ingresantes, de las dos carreras de Ingeniería que ofrece la Universidad Nacional de Luján, observándose una significativa correlación entre el rendimiento académico del estudiante en el primer cuatrimestre y el abandono de los estudios durante el segundo, tercero y cuarto cuatrimestre. En este trabajo, presentamos los resultados que se alcanzaron al aplicar el mismo modelo a las diez cohortes, equivalentes, de estudiantes de las dos carreras del campo de las Ciencias Económicas que se ofrecen en la misma Institución: Licenciatura en Administración y Licenciatura en Comercio Internacional. Las principales conclusiones a las que arribamos es que el modelo se valida positivamente al cambiar el origen disciplinar de las carreras en las que se aplica. Por otra parte, existe mayor correlación entre el rendimiento académico en el primer cuatrimestre y el momento en que se abandonan los estudios para los estudiantes de carreras de Ciencias Económicas que la observada en los de Ingeniería. Se repite el fenómeno observado para las carreras de Ingeniería, de disminuir la correlación entre el rendimiento académico y el abandono para la cohorte 2002. También se detecta una diferencia significativa respecto de la moda para la cantidad de asignaturas aprobadas durante el primer cuatrimestre para las cuatro carreras

Alluvial fan records from southeast Arabia reveal multiple windows for human dispersal

The dispersal of human populations out of Africa into Arabia was most likely linked to episodes of climatic amelioration, when increased monsoon rainfall led to the activation of drainage systems, improved freshwater availability, and the development of regional vegetation. Here we present the first dated terrestrial record from southeast Arabia that provides evidence for increased rainfall and the expansion of vegetation during both glacial and interglacial periods. Findings from extensive alluvial fan deposits indicate that drainage system activation occurred during Marine Isotope Stage (MIS) 6 (ca. 160–150 ka), MIS 5 (ca. 130–75 ka), and during early MIS 3 (ca. 55 ka). The development of active freshwater systems during these periods corresponds with monsoon intensity increases during insolation maxima, suggesting that humid periods in Arabia were not confined to eccentricity-paced deglaciations, and providing paleoenvironmental support for multiple windows of opportunity for dispersal out of Africa during the late Pleistocene