Measurement framework for assessing disruptive innovations

Assessing potential disruptiveness of innovations is an important but challenging task for incumbents. However, the extant literature focuses only on technological and marketplace aspects, and most of the documented methods tend to be case specific. In this study, we present a multidimensional measurement framework to assess the disruptive potential of product innovations. The framework is designed based on the concept that the nature of disruptive innovations is multidimensional. Three aspects are considered, i.e., technological features, marketplace dynamics and external environment. Ten indicators of the three categories are proposed and then connected based on the conceptual and literature analysis. Three innovations, namely, WeChat (successful), Modularised Mobile Phone (failed) and Virtual Reality/Augmented Reality (ongoing), are selected as case studies. A panel of industrial experts with PhD degree in engineering is surveyed. The survey results are calculated and analysed according to the framework and then compared against the developments of the innovations. We also check the robustness of this framework by surveying other groups of people, and the results are nearly identical to the previous findings. This study enables a systematic assessment of disruptive potential of innovations using the framework, providing insights for decisions in product launch and resource allocation.fi=vertaisarvioitu|en=peerReviewed

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead