Polysaccharide Blend Fibres Formed from NaOH, N-Methylmorpholine-N-oxide and 1-Ethyl-3-methylimidazolium acetate

Article disponible sur le site de l'éditeur : http://www.fibtex.lodz.pl/article330.htmlInternational audienceThe aim of the study was to find new structured biopolymer blends bearing adjustable properties able to produce innovative materials. Apart from cellulose and three solvents (NaOH, N-methylmorpholine-N-oxide [NMMO] and 1-ethyl-3-methylimidazolium acetate [EMIMac]), 15 different polysaccharides were chosen to study the interactions ofpolysaccharides or their mixtures in solutions, as well as the solid state after forming. Dissolution screenings yielded promising polysaccharides, which were used for the preparation of cellulose/ polysaccharide solutions and subsequently for the shaping of blends with cellulose. The solubility and miscibility were evaluated by microscopy, DSC, particle analysis and rheology. Polysaccharides with a structure similar to that of cellulose, e.g., xylan, carrageenan or cellulose carbamate were not miscible, showing globular morphologies, whereas high-molar and side chains containing polysaccharides such as xanthan or tragacanth gum form co-continuous morphologies. The forming of blend fibres was nevertheless possible for all three solvents. The textile-physical properties of the blend fibres were slightly decreased compared to those of the unmodified fibre, in which fibres from NMMO and EMIMac had the highest performance. The presence of blended polysaccharides in the fibres produced was verified by residue sugar analysis, in which the highest amounts occurred for EMIMac fibres

Exciton Spin Dynamics in Semiconductor Quantum Wells

In this paper we will review Exciton Spin Dynamics in Semiconductor Quantum Wells. The spin properties of excitons in nanostructures are determined by their fine structure. We will mainly focus in this review on GaAs and InGaAs quantum wells which are model systems.Comment: 55 pages, 27 figure

Will Patients Benefit from Regionalization of Gynecologic Cancer Care?

OBJECTIVE: Patient chances for cure and palliation for a variety of malignancies may be greatly affected by the care provided by a treating hospital. We sought to determine the effect of volume and teaching status on patient outcomes for five gynecologic malignancies: endometrial, cervical, ovarian and vulvar carcinoma and uterine sarcoma. METHODS: The Florida Cancer Data System dataset was queried for all patients undergoing treatment for gynecologic cancers from 1990-2000. RESULTS: Overall, 48,981 patients with gynecologic malignancies were identified. Endometrial tumors were the most common, representing 43.2% of the entire cohort, followed by ovarian cancer (30.9%), cervical cancer (20.8%), vulvar cancer (4.6%), and uterine sarcoma (0.5%). By univariate analysis, although patients treated at high volume centers (HVC) were significantly younger, they benefited from an improved short-term (30-day and/or 90-day) survival for cervical, ovarian and endometrial cancers. Multivariate analysis (MVA), however, failed to demonstrate significant survival benefit for gynecologic cancer patients treated at teaching facilities (TF) or HVC. Significant prognostic factors at presentation by MVA were age over 65 (HR = 2.6, p<0.01), African-American race (HR = 1.36, p<0.01), and advanced stage (regional HR = 2.08, p<0.01; advanced HR = 3.82, p<0.01, respectively). Surgery and use of chemotherapy were each significantly associated with improved survival. CONCLUSION: No difference in patient survival was observed for any gynecologic malignancy based upon treating hospital teaching or volume status. Although instances of improved outcomes may occur, overall further regionalization would not appear to significantly improve patient survival

On the massive stellar population of the Super Star Cluster Westerlund 1

We present new spectroscopic and photometric observations of the young Galactic open cluster Westerlund 1 (Wd 1) that reveal a unique population of massive evolved stars. We identify ~200 cluster members and present spectroscopic classifications for ~25% of these. We find that all stars so classified are unambiguously post-Main Sequence objects, consistent with an apparent lack of an identifiable Main Sequence in our photometric data to V~20. We are able to identify rich populations of Wolf Rayet stars, OB supergiants and short lived transitional objects. Of these, the latter group consists of both hot (Luminous Blue Variable and extreme B supergiants) and cool (Yellow Hypergiant and Red Supergiant) objects - we find that half the known Galactic population of YHGs resides within Wd1. We obtain a mean V-M_V ~25 mag from the cluster Yellow Hypergiants, implying a Main Sequence turnoff at or below M_V =-5 (O7 V or later). Based solely on the masses inferred for the 53 spectroscopically classified stars, we determine an absolute minimum mass of \~1.5 x 10^3 Msun for Wd 1. However, considering the complete photometrically and spectroscopically selected cluster population and adopting a Kroupa IMF we infer a likely mass for Wd 1 of ~10^5 Msun, noting that inevitable source confusion and incompleteness are likely to render this an underestimate. As such, Wd 1 is the most massive compact young cluster yet identified in the Local Group, with a mass exceeding that of Galactic Centre clusters such as the Arches and Quintuplet. Indeed, the luminosity, inferred mass and compact nature of Wd 1 are comparable with those of Super Star Clusters - previously identified only in external galaxies - and is consistent with expectations for a Globular Cluster progenitor.Comment: A&A in press, 24 pages with 19 figures. For full resolution version see http://www.edpsciences.org/articles/aa/pdf/press-releases/PRAA200506.pdf (now correct url

Anticipatory versus Reactive Spatial Attentional Bias to Threat

This is the peer reviewed version of the following article: Gladwin, T.E., Mobius, M., McLoughlin, S., & Tyndall, I. (2019). Anticipatory versus reactive spatial attentional bias to threat. British Journal of Psychology 110(1) pp. 3-14, which has been published in final form at https://doi.org/10.1111/bjop.12309 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-ArchivingDot-probe or visual probe tasks (VPTs) are used extensively to measure attentional biases. A novel variant termed the cued VPT (cVPT) was developed to focus on the anticipatory component of attentional bias. This study aimed to establish an anticipatory attentional bias to threat using the cVPT and compare its split-half reliability with a typical dot-probe task. A total of 120 students performed the cVPT task and dot-probe tasks. Essentially, the cVPT uses cues that predict the location of pictorial threatening stimuli, but on trials on which probe stimuli are presented the pictures do not appear. Hence, actual presentation of emotional stimuli did not affect responses. The reliability of the cVPT was higher at most cue–stimulus intervals and was .56 overall. A clear anticipatory attentional bias was found. In conclusion, the cVPT may be of methodological and theoretical interest. Using visually neutral predictive cues may remove sources of noise that negatively impact reliability. Predictive cues are able to bias response selection, suggesting a role of predicted outcomes in automatic processes

Cell–cell and cell–matrix dynamics in intraperitoneal cancer metastasis

The peritoneal metastatic route of cancer dissemination is shared by cancers of the ovary and gastrointestinal tract. Once initiated, peritoneal metastasis typically proceeds rapidly in a feed-forward manner. Several factors contribute to this efficient progression. In peritoneal metastasis, cancer cells exfoliate into the peritoneal fluid and spread locally, transported by peritoneal fluid. Inflammatory cytokines released by tumor and immune cells compromise the protective, anti-adhesive mesothelial cell layer that lines the peritoneal cavity, exposing the underlying extracellular matrix to which cancer cells readily attach. The peritoneum is further rendered receptive to metastatic implantation and growth by myofibroblastic cell behaviors also stimulated by inflammatory cytokines. Individual cancer cells suspended in peritoneal fluid can aggregate to form multicellular spheroids. This cellular arrangement imparts resistance to anoikis, apoptosis, and chemotherapeutics. Emerging evidence indicates that compact spheroid formation is preferentially accomplished by cancer cells with high invasive capacity and contractile behaviors. This review focuses on the pathological alterations to the peritoneum and the properties of cancer cells that in combination drive peritoneal metastasis

Prediction of second neurological attack in patients with clinically isolated syndrome using support vector machines

The aim of this study is to predict the conversion from clinically isolated syndrome to clinically definite multiple sclerosis using support vector machines. The two groups of converters and non-converters are classified using features that were calculated from baseline data of 73 patients. The data consists of standard magnetic resonance images, binary lesion masks, and clinical and demographic information. 15 features were calculated and all combinations of them were iteratively tested for their predictive capacity using polynomial kernels and radial basis functions with leave-one-out cross-validation. The accuracy of this prediction is up to 86.4% with a sensitivity and specificity in the same range indicating that this is a feasible approach for the prediction of a second clinical attack in patients with clinically isolated syndromes, and that the chosen features are appropriate. The two features gender and location of onset lesions have been used in all feature combinations leading to a high accuracy suggesting that they are highly predictive. However, it is necessary to add supporting features to maximise the accuracy. © 2013 IEEE