30 research outputs found

    CONSIDERATIONS REGARDING THE DEVELOPMENT OF NEW EQUIPMENT USED FOR HEMP HARVESTING

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    The important potential of cultivating hemp for fiber and cannabidiol extraction for medicinal use, makes this plant return to the attention of agronomists and medical researchers. Another strength of this plant is the potential of produced fibers to contribute to the decrease in the use of plastic in the near future, helping to reduce dependence on fossil fuels. In addition, hemp could be a more economically attractive alternative for ethanol generation or even for the production of high-strength construction materials. The paper aims to present several technologies used for hemp harvesting

    REVIEW OF THE MAIN EQUIPMENT USED FOR SEPARATING CONTAMINANTS FROM WHEAT SEEDS, CLASSIFICATION ACCORDING TO THEIR FUNCTIONAL ROLE

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    Wheat seed cleaning require a complex set of operations to be performed in order to remove impurities from the grain mass and obtain high quality final products. These operations are carried out in a technological flow, starting from harvesting until the final processing stage, depending on the crop destination. The stages used to clean the wheat grain are usually following the operations: cleaning in aerodynamic separators, cleaning with sieves, sorting in indent cylinder separator, additional cleaning in special cleaning machines. The paper presents a synthesis of the primary processing phases of wheat seeds for the use in the food industry depending on their functional role

    Classification of autism spectrum disorder using supervised learning of brain connectivity measures extracted from synchrostates

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    This is the author accepted manuscript. The final version is available from IOP Publishing via the DOI in this record.OBJECTIVE: The paper investigates the presence of autism using the functional brain connectivity measures derived from electro-encephalogram (EEG) of children during face perception tasks. APPROACH: Phase synchronized patterns from 128-channel EEG signals are obtained for typical children and children with autism spectrum disorder (ASD). The phase synchronized states or synchrostates temporally switch amongst themselves as an underlying process for the completion of a particular cognitive task. We used 12 subjects in each group (ASD and typical) for analyzing their EEG while processing fearful, happy and neutral faces. The minimal and maximally occurring synchrostates for each subject are chosen for extraction of brain connectivity features, which are used for classification between these two groups of subjects. Among different supervised learning techniques, we here explored the discriminant analysis and support vector machine both with polynomial kernels for the classification task. MAIN RESULTS: The leave one out cross-validation of the classification algorithm gives 94.7% accuracy as the best performance with corresponding sensitivity and specificity values as 85.7% and 100% respectively. SIGNIFICANCE: The proposed method gives high classification accuracies and outperforms other contemporary research results. The effectiveness of the proposed method for classification of autistic and typical children suggests the possibility of using it on a larger population to validate it for clinical practice.The work presented in this paper was supported by FP7 EU funded MICHELANGELO project, Grant Agreement #288241. URL: www.michelangelo-project.eu/

    RESEARCH OF THE MAIN PROCESSING WORKS FOR ESTABLISHING A JERUSALEM ARTICHOKE CROP ON DIFFICULT AND CONTAMINATED SOILS

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    Jerusalem artichoke, is a technical plant that have some special features which make it suitable to be cultivated on degraded and difficult soils. However, processing difficult lands can cause major problems for farmers, in terms of using the right technology and reducing investment costs. The paper aim to address to the main challenges faced in preparing the soil for a Jerusalem artichoke culture, in order to maximize the productivity and efficiency

    CONSTRUCTION TYPES OF TECHNICAL EQUIPMENT FOR DOSING, WEIGHING, PACKAGING AND PROCEDURES USED IN MILLING UNITS

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    The paper presents several types of technical equipment for dosing, weighing, packaging and the procedures used in the milling units. The weighing systems take into account several important criteria for their design, namely: how the weight or mass of the load is offset and how the result is transferred

    CONSIDERATIONS ON ENERGETIC CROPS POTENTIAL

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    In order to breathe fresh and clean air, nature and terrestrial atmosphere should be preserved and protected. Carbon emissions represent one of the main enemies of air quality. Recently, carbon emissions have surpassed all the predictions because the excessive industrialization, becoming the determining factor for global warming. A viable alternative to carbon emissions reduction is the utilization of energy sources that can diminish the noxious substances emissions up to zero. This can be done by using the power of wind, sun, water, energy plants, etc. Among the energetic potential plants, the biomass is obtained- a form of renewable energy which final product is biofuel

    Susceptibility to fatty acid-induced β-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: A potential link between β-cell lipotoxicity and islet inflammation

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    β-Cell lipotoxicity is thought to play an important role in the development of type 2 diabetes. However, no study has examined its role in type 1 diabetes, which could be clinically relevant for slow-onset type 1 diabetes. Reports of enhanced cytokine toxicity in fat-laden islets are consistent with the hypothesis that lipid and cytokine toxicity maybe synergistic. Thus, β-cell lipotoxicity could be enhanced in models of autoimmune diabetes. To determine this, we examined the effects of prolonged free fatty acids elevation on β-cell secretory function in the prediabetic diabetes-prone BioBreeding (dp-BB) rat, its diabetes-resistant BioBreeding (dr-BB) control, and normal Wistar-Furth (WF) rats. Rats received a 48-h iv infusion of saline or Intralipid plus heparin (IH) (to elevate free fatty acid levels ∼2-fold) followed by hyperglycemic clamp or islet secretion studies ex vivo. IH significantly decreased β-cell function, assessed both by the disposition index (insulin secretion corrected for IH-induced insulin resistance) and in isolated islets, in dp-BB, but not in dr-BB or WF, rats, and the effect of IH was inhibited by the antioxidant N-acetylcysteine. Furthermore, IH significantly increased islet cytokine mRNA and plasma cytokine levels (monocyte chemoattractant protein-1 and IL-10) in dp-BB, but not in dr-BB or WF, rats. All dp-BB rats had mononuclear infiltration of islets, which was absent in dr-BB and WF rats. In conclusion, the presence of insulitis was permissive for IH-induced β-cell dysfunction in the BB rat, which suggests a link between β-cell lipotoxicity and islet inflammation. Copyright © 2013 by The Endocrine Society

    EQUIPMENT FOR EXTRACTING AND PLANTING EARTH BALE ROOT PLANTS

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    Trees are one of the biggest  organisms living on the planet and their role is extremely important, namely that to maintain the purity of air we breathe, improve water quality, prevent soil erosion, reduce noise level, ensure food, construction materials and eventually people comfort. Plantation and transplantation of trees by means of specialized equipment  in comparison with human force leads to an increased planting speed and higher yield, economically speaking. This paper is designed to present different constructive variants, at world level, of equipment for extracting and planting trees with earth bale at their roots, necessary for afforestation, landscape design, tree nurseries

    Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish

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    Aminoacyl tRNA synthetases (ARSs) link specific amino acids with their cognate transfer RNAs in a critical early step of protein translation. Mutations in ARSs have emerged as a cause of recessive, often complex neurological disease traits. Here we report an allelic series consisting of seven novel and two previously reported biallelic variants in valyl-tRNA synthetase (VARS) in ten patients with a developmental encephalopathy with microcephaly, often associated with early-onset epilepsy. In silico, in vitro, and yeast complementation assays demonstrate that the underlying pathomechanism of these mutations is most likely a loss of protein function. Zebrafish modeling accurately recapitulated some of the key neurological disease traits. These results provide both genetic and biological insights into neurodevelopmental disease and pave the way for further in-depth research on ARS related recessive disorders and precision therapies
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