Family Matters: Adjustment to genetic cancer susceptibility testing

Cancer is generally feared because it is associated with death and severe physical suffering. It is one of the most common causes of death in the Netherlands. Breast and colon cancer are the most prevalent types of cancer among women. Frequently occurring types in men are cancer of colon, lung and prostate. About 5% of colorectal and breast cancer arises as a result of a mutation in an inherited cancer susceptibility gene. Knowledge about these cancer susceptibility genes has been accumulating in an impressive manner over the last decades, resulting in the clinical availability of genetic testing from the mid-nineties onward. Through genetic testing, an individual’s risk to develop cancer can be determined more precisely. This can reduce feelings of uncertainty about the r