International Migration in Ireland, 2015

This working paper is the Irish report to the OECD Expert Group on Migration. As such, the focus of the report is largely shaped by the reporting requirements for the preparation of the annual OECD International Migration Outlook. The purpose of the paper is to outline major developments and trends in migration and integration data and policy. The principal reference year is 2014, although information relating to early- 2015 is included where available and relevant. The Executive Summary provides an overview of the main findings of the report. Section 2 discusses the main developments in migration and integration policy in Ireland in 2014, including topics related to migration in the public debate. Section 3 discusses the statistics on inward and outward migration movements. Section 4 examines trends in the population. Migration and the labour market are discussed in Section 5.Department of Justice and Equalit

Ensuring the Stability of the Genome: DNA Damage Checkpoints

The cellular response to DNA damage is vital for the cell�s ability to maintain genomic integrity. Checkpoint signalling pathways, which induce a cell cycle arrest in response to DNA damage, are an essential component of this process. This is reflected by the functional conservation of these pathways in all eukaryotes from yeast to mammalian cells. This review will examine the cellular response to DNA damage throughout the cell cycle. A key component of the DNA damage response is checkpoint signalling, which monitors the state of the genome prior to DNA replication (G1/S) and chromosome segregation (G2/M). Checkpoint signalling in model systems including mice, Xenopus laevis, Drosophila melanogaster, and the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have been useful in elucidating these pathways in mammalian cells. An examination of this research, with emphasis on the function of checkpoint proteins, their relationship to DNA repair, and their involvement in oncogenesis is undertaken here

A two centre single blind randomised controlled trial to assess the effect of a patient information website on patients understanding of orthognathic surgery

Aim: To evaluate the effectiveness of a bespoke patient information website on patients understanding of orthognathic surgery and the treatment care pathway. Method: A two-centre, single blinded prospective, randomised controlled trial was conducted. A total of 51 adult patients (26 male, 25 female) aged between 15 and 45 years were recruited and enrolled in the study from the orthodontic department at the Birmingham Dental Hospital, and Solihull Hospital, United Kingdom. Patients were randomly allocated to either receive access to a bespoke patient information website or the standard British Orthodontic Society patient information leaflet on orthognathic surgery. The primary outcome measure: patients knowledge regarding orthodontic–orthognathic treatment and their attitude towards their care, was assessed using a questionnaire completed at their subsequent orthodontic appointment. Age, gender and stage of orthodontic treatment were also recorded. Results: All patients who entered the study completed the questionnaire. There was no influence on the total questionnaire score for age, gender or stage of orthodontic treatment which patients were at. No significant difference was found between the two groups with regards to their level of knowledge (p=0.06). When a per protocol analysis was carried out, the compliers in the website group scored 5.7 points higher than participants in the leaflet group for the total score. This was statistically significant (p=0.01) Conclusion: A bespoke patient information website has the potential to provide patients with more information of the orthognathic surgery care pathway when compared to the BOS patient information leaflet, however some patients may chose not to access the website. Information should be made available using both modes of delivery

Ultraviolet Imaging of the Globular Cluster 47 Tucanae

We have used the Ultraviolet Imaging Telescope to obtain deep far-UV (1620 Angstrom), 40' diameter images of the prototypical metal-rich globular cluster 47 Tucanae. We find a population of about 20 hot (Teff > 9000 K) objects near or above the predicted UV luminosity of the hot horizontal branch (HB) and lying within two half-light radii of the cluster center. We believe these are normal hot HB or post-HB objects rather than interacting binaries or blue stragglers. IUE spectra of two are consistent with post-HB phases. These observations, and recent HST photometry of two other metal-rich clusters, demonstrate that populations with rich, cool HB's can nonetheless produce hot HB and post-HB stars. The cluster center also contains an unusual diffuse far-UV source which is more extended than its V-band light. It is possible that this is associated with an intracluster medium, for which there was earlier infrared and X-ray evidence, and is produced by C IV emission or scattered light from grains.Comment: 13 pages AASLaTeX including one postscript figure and one bitmapped image, JPEG format. Submitted to the Astronomical Jorunal. Full Postscript version available at http://www.astro.virginia.edu/~bd4r

Epidemiology of the effects of residential exposure to ultrafine particles from vehicular traffic

A separate but related investigated of a database of respiratory and cardiovascular admissions revealed a significant variation by category of road but the observed associations were not what were expected.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Epidemiology of the effects of residential exposure to ultrafine particles from vehicular traffic

A separate but related investigated of a database of respiratory and cardiovascular admissions revealed a significant variation by category of road but the observed associations were not what were expected.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Ultraviolet Imagery of NGC 6752: A Test of Extreme Horizontal Branch Models

We present a 1620 A image of the nearby globular cluster NGC 6752 obtained with the Ultraviolet Imaging Telescope (UIT) during the Astro-2 mission of the Space Shuttle Endeavour in 1995 March. An ultraviolet-visible color-magnitude diagram (CMD) is derived for 216 stars matched with the visible photometry of Buonanno et al. (1986). This CMD provides a nearly complete census of the hot horizontal branch (HB) population with good temperature and luminosity discrimination for comparison with theoretical tracks. The observed data show good agreement with the theoretical zero-age horizontal branch (ZAHB) of Sweigart (1996) for an assumed reddening of E(B-V) = 0.05 and a distance modulus of 13.05. The observed HB luminosity width is in excellent agreement with the theoretical models and supports the single star scenario for the origin of extreme horizontal branch (EHB) stars. However, only four stars can be identified as post-EHB stars, whereas almost three times this many are expected from the HB number counts. If this effect is not a statistical anomaly, then some non-canonical effect may be decreasing the post-EHB lifetime. The recent non-canonical models of Sweigart (1996), which have helium-enriched envelopes due to mixing along the red giant branch, cannot explain the deficit of post-EHB stars, but might be better able to explain their luminosity distribution.Comment: 14 pages, AASTeX, includes 4 EPS figures ApJ Letters accepte

Epidemiology of the effects of residential exposure to ultrafine particles from vehicular traffic

A separate but related investigated of a database of respiratory and cardiovascular admissions revealed a significant variation by category of road but the observed associations were not what were expected