Cummulative incidence of peptic ulcer compared between patients with and without EOC.

Patients with EOC had a higher cumulative incidence of peptic ulcer than those without EOC.</p

Comparison of incidence and hazard ratio of peptic ulcer disease stratified by sex, age and comorbidity between patients with and without early-onset cataract.

Comparison of incidence and hazard ratio of peptic ulcer disease stratified by sex, age and comorbidity between patients with and without early-onset cataract.</p

Demographic characteristics and comorbidities of patients with and without early-onset cataract.

Demographic characteristics and comorbidities of patients with and without early-onset cataract.</p

Flow chart of patients of two cohorts.

Flow chart of patients of two cohorts.</p

Incidence of retinopathy of prematurity by birth weight and Cox proportional hazards regression analysis estimated adjusted hazard ratio associated with mechanical ventilation.

Incidence of retinopathy of prematurity by birth weight and Cox proportional hazards regression analysis estimated adjusted hazard ratio associated with mechanical ventilation.</p

Incidence of retinopathy of prematurity by birth weight and Cox proportional hazards regression analysis estimated adjusted hazard ratio associated with of ROP using normal birthweight of singleton as reference.

Incidence of retinopathy of prematurity by birth weight and Cox proportional hazards regression analysis estimated adjusted hazard ratio associated with of ROP using normal birthweight of singleton as reference.</p

Incidence and Cox proportional hazards regression analysis estimated adjusted hazard ratio of retinopathy of prematurity associated with mechanical ventilation use at birth.

Incidence and Cox proportional hazards regression analysis estimated adjusted hazard ratio of retinopathy of prematurity associated with mechanical ventilation use at birth.</p

Incidence of retinopathy of prematurity and Cox proportional hazards regression analysis estimated twin to singleton adjusted hazard ratio by demographic status.

Incidence of retinopathy of prematurity and Cox proportional hazards regression analysis estimated twin to singleton adjusted hazard ratio by demographic status.</p

Demographic status of singleton and twin cohorts.

Demographic status of singleton and twin cohorts.</p

DataSheet_1_Association between immune checkpoint inhibitor medication and uveitis: a population-based cohort study utilizing TriNetX database.pdf

ObjectiveTo explore the associations between the use of immune checkpoint inhibitors (ICIs) and the risk of developing uveitis among cancer patients.MethodsCancer patients who received ICI therapy and a comparison group of cancer patients who did not receive ICI therapy were retrospectively recruited from the TriNetX electronic heath-record registry. The outcome of interest was the development of new-onset uveitis. Propensity score matching based on a 1:1 ratio was conducted in order to reduce bias. Multi-variate cox proportional hazard models and Kaplan Meier method were also utilized to assess for the risk of uveitis among cancer patients who received ICI therapy.Results71931 cancer patients (54.7% male; 76.5% white; mean age at index 63.6 ± 12.2 years) who received ICI treatment (ICI group) and 71931 cancer patients (54.7% male; 77% white; mean age at index 63.5 ± 12.4 years) who never received ICI (comparison group) were recruited. Associated Kaplan-Meier curves showed significantly increased uveitis risk among the ICI group for all follow-up years (pConclusionA significantly increased risk for uveitis diseases was found among the ICI group from the first year of follow-up. Increased awareness should be promoted on the occurrence of uveitis among cancer patients receiving ICI therapy.</p