20 research outputs found
Иновации в езиковото и специализирано обучение: теоретични аспекти и паралели
The report presents some of the theoretical aspects related to the topic, as well as the practical orientation of innovations related to language and specialized training in various public spheres. Among the highlights of the topic are the analysis and parallels with approaches, including in the context of the "Innovations in language and specialized training" project of TU-Gabrovo.Настоящата тема, е разработена и реализирана като част от проекта „Иновации в езиковото и специализирано обучение“ (I етап) за научни изследвания по научните направления на Технически университет – Габрово
Post COVID-19 Conditions and the Cardiovascular System
One out of four patients affected by COVID-19 will experience persistent (>3-4 weeks) signs and symptoms (Post COVID-19 conditions or Post-Acute Sequelae of SARS-CoV-2 – PASC) and this fact will have a major significance for the healthcare and economic systems in the upcoming years. The cardiovascular system is one of the key targets for the Post COVID-19 syndrome, given the pathogenesis of the virus and prevalence of ACE-2 receptors. According to our initial personal experience via the campaign “Life after COVID” of the Bulgarian Cardiac Institute, a substantial proportion of patients having suffered from COVID-19 develop long-term cardiovascular consequences. They could range from rhythm disorder and blood pressure variation, through impairment of myocardial mechanics and heart failure, and to acute vascular manifestations of Post COVID-19 conditions, such as acute coronary syndrome, acute pulmonary embolism, and acute limb ischemia. These cardiovascular complications require special and dedicated medical attention, and we could share our personal experience on the matter
Модернизација на главниот транспорт на ровната руда во рудникот Саса со примена на јамски камиони
Во трудот е презентирана модернизацијата на главниот транспорт на ровната руда во рудникот "Саса" со примена на современи транспортни средства - јамски камиони. Прикажан е развојниот пат во примената на јамските камиони, а посебен акцент е ставен на главниот транспорт на ровната руда на хор.XIVb, ревир Свиња Река
How to decide which COVID-19 patient with myocardial infarction to send to the Cath Lab? - A case series of COVID-19 patients with myocardial infarction (Preprint)
BACKGROUND
The Coronavirus pandemic has hit the world with its vast contagiousness, high morbidity, and mortality. Apart from the direct damage to the lung tissue, the corona virus infection is able to predispose patients to thrombotic disease, thus causing cerebral or coronary incidents.
OBJECTIVE
The aim of this study was to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with myocardial infarction (MI), who have an infarct-related artery (IRA) and therefore, require immediate revascularization, and those, who have no IRA.
METHODS
This was a single-center, observational study of 10 consecutive patients with COVID-19, who were admitted with confirmed MI.
RESULTS
In our study group the mean age was 67.5 ± 8.3 years, half of the patients were female; all of them had arterial hypertension; 8 patients (80%) had dyslipidemy; 4 (40%) had diabetes. 30% of the patients with MI did not have an IRA, and did not require pPCI. Patients with MI and IRA had significantly higher hsTrI values (48.9 ± 43.2 vs 0.6 ± 0.7, p=0.007) and exclusively typical chest pain 100% vs 0%, p=0.007), compared to patients with MI without an IRA. The ECG changes had only marginal statistical significance. Our results suggest that using a higher cut-off value for hsTrI (>7.5 times upper reference range) increases the specificity and positive predictive value for diagnosing a MI with the presence of IRA and need for pPCI, to 100%
CONCLUSIONS
In our analysis we confirm that a higher cut-off value for hsTrI helps distinguish between COVID patients with MI, who have IRA and therefore, require immediate revascularization, compared to those, who have no IRA.
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How to decide which COVID-19 patient with myocardial infarction to send to the Cath Lab? - A case series of COVID-19 patients with myocardial infarction
AbstractINTRODUCTIONThe Coronavirus pandemic has hit the world with its vast contagiousness, high morbidity, and mortality. Apart from the direct damage to the lung tissue, the corona virus infection is able to predispose patients to thrombotic disease, thus causing cerebral or coronary incidents.AIMSThe aim of this study was to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with myocardial infarction (MI), who have an infarct-related artery (IRA) and therefore, require immediate revascularization, and those, who have no IRA.METHODSThis was a single-center, observational study of 10 consecutive patients with COVID-19, who were admitted with confirmed MI.RESULTSIn our study group the mean age was 67.5 ± 8.3 years, half of the patients were female; all of them had arterial hypertension; 8 patients (80%) had dyslipidemy; 4 (40%) had diabetes. 30% of the patients with MI did not have an IRA, and did not require pPCI. Patients with MI and IRA had significantly higher hsTrI values (48.9 ± 43.2 vs 0.6 ± 0.7, p=0.007) and exclusively typical chest pain 100% vs 0%, p=0.007), compared to patients with MI without an IRA. The ECG changes had only marginal statistical significance. Our results suggest that using a higher cut-off value for hsTrI (>7.5 times upper reference range) increases the specificity and positive predictive value for diagnosing a MI with the presence of IRA and need for pPCI, to 100%CONCLUSIONIn our analysis we confirm that a higher cut-off value for hsTrI helps distinguish between COVID patients with MI, who have IRA and therefore, require immediate revascularization, compared to those, who have no IRA.</jats:sec
Agency conflicts and cash: Estimates from a structural model, Working paper
We estimate a dynamic model of firm investment and cash accumulation to ascertain whether agency problems affect corporate cash policy. We model three specific mechanisms that misalign managerial and shareholder incentives: limited managerial ownership of the firm, compensation based on firm size, and managerial perquisite consumption. Our estimates indicate that agency issues related to perquisites are more important for explaining corporate cash balances but that agency issues related to firm size are more important for firm value. We find that firms with lower blockholder and institutional ownership have higher managerial perquisite consumption. We also find that lower managerial ownership is a key factor in the secular upward trend in cash holding. Electronic copy available at