L'Écho : grand quotidien d'information du Centre Ouest

11 février 19401940/02/11 (A69).Appartient à l’ensemble documentaire : PoitouCh

Additional file 1: of Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer

Properties of GBC cell lines used in the study. (XLS 27 kb

Additional file 8: of Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer

Representative images of MIF by immunohistochemistry. Representative sections from cholecystitis tissues (moderate staining) – (i) stained with hematoxylin and eosin; (ii) probed with anti-MIF antibody. Representative sections from gallbladder adenocarcinoma tissue (weak staining); (iii) stained with hematoxylin and eosin; (iv) probed with anti-MIF antibody. (PDF 1714 kb

Additional file 16: Figure S7. of A multi-omic analysis of human naĂŻve CD4+ T cells

Comparison of a protein’s abundance versus its transcriptional abundance. Scatterplot of protein abundance versus transcript abundance is shown. Transcript abundance is represented as FPKM (log2) on the x-axis and protein abundance is represented as normalized iBAQ (log2) on the y-axis. (PDF 487 kb

Additional file 2: Figure S2. of A multi-omic analysis of human naĂŻve CD4+ T cells

Sequence variants identified in the genome and classification of SNPs in protein coding regions. (A) Total number of SNPs, insertions, deletions and substitutions identified from whole genome sequencing data. (B) Proportion of synonymous and non-synonymous SNPs identified in the coding region of the genome among non-synonymous SNPs (nsSNPs), proportion of conservative and non-conservative homozygous and heterozygous changes are shown. (C) nsSNP frequency across various molecular classes of genes. (PDF 68 kb

Additional file 18: Figure S9. of A multi-omic analysis of human naïve CD4+ T cells

DNA methylation pattern across various gene features on all protein coding genes in naïve CD4+ T cells. The x-axis represents various gene features in protein coding genes (TSS1500 - 1,500 bp upstream of transcription start site, TSS200 - 200 bp upstream of transcription start site, 5′ UTR – 5′ untranslated region, 1st exon, gene body and 3′ UTR – 3′ untranslated region) and the y-axis represents beta value which is an estimate of methylation level. Box-Whisker plots show median methylation levels at each gene feature across all protein coding genes in naïve CD4+ T cells. (PDF 1313 kb

Additional file 20: Figure S11. of A multi-omic analysis of human na誰ve CD4+ T cells

Correlation of methylation and transcript levels of genes between memory and na誰ve CD4+ T cells. (A) Intersection of promoter methylation and mRNA expression data from na誰ve and memory T cells. Genes marked in red in the upper left quadrant showed significantly reduced expression in na誰ve CD4+ T cells due to promoter hypermethylation. Genes that showed the opposite trend are shown in the bottom right quadrant. (PDF 185 kb

L'Écho : grand quotidien d'information du Centre Ouest

06 juin 19201920/06/06 (A49).Appartient à l’ensemble documentaire : PoitouCh

L'Écho : grand quotidien d'information du Centre Ouest

10 juin 19431943/06/10 (A72,N518).Appartient à l’ensemble documentaire : PoitouCh

Additional file 13: Table S7. of A multi-omic analysis of human naĂŻve CD4+ T cells

A list of peptides supporting novel exons or exon extensions identified using proteogenomics strategy. (XLSX 9 kb