Measuring the recreational use value of migratory shorebirds on the Delaware Bay

In this article we estimate the recreational use value of household trips to view shorebirds during the annual horseshoe crab/shorebird migration on the Delaware Bay. We use contingent valuation to estimate the value of day and overnight trips separately and use a discrete choice question followed by a payment-card question to generate our valuation data. Our best estimates for the value of a day trip are about $66–$90/household and for an overnight trip about $200–$425/household (2008$). Our data are from the 2008 season, and our average household size is 1.66. For some context, estimates from four other studies report values that vary from$63/trip/person to $442/trip/person. These studies vary in method and specific birding populations studied and mix day and overnight trips.Contingent valuation, discrete choice, bird watching, use value

Measuring the Recreational Use Value of Migratory Shorebirds on the Delaware Bay

In this article we estimate the recreational use value of household trips to view shorebirds during the annual horseshoe crab/shorebird migration on the Delaware Bay. We use contingent valuation to estimate the value of day and overnight trips separately and use a discrete choice question followed by a payment-card question to generate our valuation data. Our best estimates for the value of a day trip are about $66–$90/household and for an overnight trip about $200–$425/household (2008$). Our data are from the 2008 season, and our average household size is 1.66. For some context, estimates from four other studies report values that vary from$63/trip/person to $442/trip/person. These studies vary in method and specific birding populations studied and mix day and overnight trips.Contingent valuation, discrete choice, bird watching, use value, Environmental Economics and Policy, Public Economics, Research Methods/ Statistical Methods, Q5,

The economic value of viewing migratory shorebirds on the Delaware Bay: An application of the single site travel cost model using on-site data

We estimated a count data model of recreation demand using data from an on-site survey of recreational birders who had visited southern Delaware during the month–long annual horseshoe crab/shorebird spring migration in 2008. We analyzed daytrips only. Our estimates from the models ranged from $32 to$142/trip/household or about $131 to$582/season/household (2008$). The variation was due to differences in the value of time. The average household size was 1.66. We found that the valuation results were sensitive to the inclusion of covariates in the model. Our results are useful for damage assessments and benefit–cost analyses where birdwatching is affected.recreational birding, economic value, shorebird migration, onsite sampling, endogenous stratification

"The Economic Value of Viewing Migratory Shorebirds on the Delaware Bay: An Application of the Single Site Travel Cost Model Using On-Site Data"

Using data from an on-site survey of recreational birders in southern Delaware during the annual horseshoe crab/shorebird spring migration, we estimated four truncated count data models of recreation demand accounting for endogenous stratification due to onsite sampling. We analyzed day-trips only and conducted sensitivity analysis on measurement of the value of time and inclusion of covariates. Our estimates from the models using all covariates were in the range of $40 to$178/trip/household (2008$). The variation is due to differences in the value of time. The average household size is 1.66.Travel-Cost Model, Shorebirds, Valuation

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

Chromosomal-level assembly of the Asian Seabass genome using long sequence reads and multi-layered scaffolding

We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical and genetic mapping along with shared synteny from closely related fish species to derive a chromosome-level assembly with a contig N50 size over 1 Mb and scaffold N50 size over 25 Mb that span ~90% of the genome. The population structure of L. calcarifer species complex was analyzed by re-sequencing 61 individuals representing various regions across the species' native range. SNP analyses identified high levels of genetic diversity and confirmed earlier indications of a population stratification comprising three clades with signs of admixture apparent in the South-East Asian population. The quality of the Asian seabass genome assembly far exceeds that of any other fish species, and will serve as a new standard for fish genomics

The economic value of viewing migratory shorebirds on the Delaware Bay: An application of the single site travel cost model using on-site data

We estimated a count data model of recreation demand using data from an on-site survey of recreational birders who had visited southern Delaware during the month–long annual horseshoe crab/shorebird spring migration in 2008. We analyzed daytrips only. Our estimates from the models ranged from $32 to$142/trip/household or about $131 to$582/season/household (2008$). The variation was due to differences in the value of time. The average household size was 1.66. We found that the valuation results were sensitive to the inclusion of covariates in the model. Our results are useful for damage assessments and benefit–cost analyses where birdwatching is affected

Measuring the recreational use value of migratory shorebirds on the Delaware Bay

In this article we estimate the recreational use value of household trips to view shorebirds during the annual horseshoe crab/shorebird migration on the Delaware Bay. We use contingent valuation to estimate the value of day and overnight trips separately and use a discrete choice question followed by a payment-card question to generate our valuation data. Our best estimates for the value of a day trip are about $66–$90/household and for an overnight trip about $200–$425/household (2008$). Our data are from the 2008 season, and our average household size is 1.66. For some context, estimates from four other studies report values that vary from$63/trip/person to $442/trip/person. These studies vary in method and specific birding populations studied and mix day and overnight trips

The economic value of viewing migratory shorebirds on the Delaware Bay: An application of the single site travel cost model using on-site data

We estimated a count data model of recreation demand using data from an on-site survey of recreational birders who had visited southern Delaware during the month–long annual horseshoe crab/shorebird spring migration in 2008. We analyzed daytrips only. Our estimates from the models ranged from $32 to$142/trip/household or about $131 to$582/season/household (2008$). The variation was due to differences in the value of time. The average household size was 1.66. We found that the valuation results were sensitive to the inclusion of covariates in the model. Our results are useful for damage assessments and benefit–cost analyses where birdwatching is affected

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN