Group testing problems in experimental molecular biology

In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing is for screening libraries of clones with hybridization probes. This is a crucial step in constructing physical maps and for finding genes. Group testing has also been considered for sequencing by hybridization. Another important application includes screening libraries of reagents for useful chemically active zones. This preliminary report discusses some of the constrained group testing problems which arise in biology.Comment: 7 page

Radix Sorting With No Extra Space

It is well known that n integers in the range [1,n^c] can be sorted in O(n) time in the RAM model using radix sorting. More generally, integers in any range [1,U] can be sorted in O(n sqrt{loglog n}) time. However, these algorithms use O(n) words of extra memory. Is this necessary? We present a simple, stable, integer sorting algorithm for words of size O(log n), which works in O(n) time and uses only O(1) words of extra memory on a RAM model. This is the integer sorting case most useful in practice. We extend this result with same bounds to the case when the keys are read-only, which is of theoretical interest. Another interesting question is the case of arbitrary c. Here we present a black-box transformation from any RAM sorting algorithm to a sorting algorithm which uses only O(1) extra space and has the same running time. This settles the complexity of in-place sorting in terms of the complexity of sorting.Comment: Full version of paper accepted to ESA 2007. (17 pages

First Author Advantage: Citation Labeling in Research

Citations among research papers, and the networks they form, are the primary object of study in scientometrics. The act of making a citation reflects the citer's knowledge of the related literature, and of the work being cited. We aim to gain insight into this process by studying citation keys: user-chosen labels to identify a cited work. Our main observation is that the first listed author is disproportionately represented in such labels, implying a strong mental bias towards the first author.Comment: Computational Scientometrics: Theory and Applications at The 22nd CIKM 201