Inclusion of C₆₀ into MCM-41 by Solvophobic Nature

Conventional method of incorporation of organic molecules to inorganic porous materials requires high temperature and highly reduced pressure. An efficient process that avoids the serious technical problems is strongly desired. In this study, our group reports an unprecedented method for the efficient combination of C60 with MCM-41. The concept of the method is based on the solvophobic interaction between a nonpolar solute and an inorganic solid surface in a polar solvent. Very high levels (26 wt %) of C60 in MCM-41 were achieved using this method. Strong evidence for intrachannel inclusion was provided by the measurement of various characteristics of the resulting composites

Unprecedented CO₂-Promoted Aminochlorination of Olefins with Chloramine-T

A new synthetic procedure for the aminochlorination of olefins for the synthesis of vicinal chloroamine derivatives using a combination of Chloramine-T and carbon dioxide is described. The method can be applied to a variety of olefins, including an electron-sufficient olefin and a conjugated diene

Lewis Base Catalyzed Ring Opening of Aziridines with Silylated Nucleophiles

The ring opening of N-tosylaziridines with trimethylsilylated nucleophiles, catalyzed by N,N,N‘,N‘-tetramethylethylenediamine, led to the production of β-functionalized sulfonamides in good to excellent yields with high regioselectivity

Unique Ionic Iodine Atom Transfer Cyclization: A New Route to Iodomethylated Pyrrolidine Derivatives from γ-Iodoolefin and Chloramine-T

Pyrrolidines and bicyclic pyrrolidine derivatives can effectively be synthesized from γ-iodoolefins using commercially available chloramine-T (CT) as a nitrogen source. The cyclization proceeds with high stereoselectivity via a cyclic iodonium intermediate

Novel Synthesis of <i>g</i><i>em</i>-Dichloroaziridines from Imines via the KF/Al₂O₃-Promoted Generation of Dichlorocarbene from Chloroform

KF/Al2O3 was found to be an efficient base for the reaction of imines with chloroform in acetonitrile to give gem-dichloroaziridines 2 in moderate to high yields. The KF/Al2O3-promoted dichloroaziridination can be carried out with simple workup, tolerates a variety of functional groups present in the imines, and proceeds smoothly with a smaller amount of carbene source

Practical and Convenient Synthesis of <i>N</i>-Heterocycles: Stereoselective Cyclization of <i>N</i>-Alkenylamides with <i>t</i>-BuOI under Neutral Conditions

tert-Butyl hypoiodite (t-BuOI) was found to be a powerful reagent for the cyclization of N-alkenylamides leading to a variety of N-heterocycles under extremely mild conditions. When N-alkenylsulfonamides were employed in the reaction, three- to six-membered saturated N-heterocycles were obtained in good to excellent yields with complete stereoselectivity. The method was applicable to the cyclization of alkenylbenzamide derivatives to afford N-, O- or N-, S-heterocycles

Radical Carboxylation: Ester Synthesis from Alkyl Iodides, Carbon Monoxide, and Alcohols under Irradiation Conditions

Radical Carboxylation:  Ester Synthesis from Alkyl Iodides, Carbon Monoxide, and Alcohols under Irradiation Condition

Nitrogen-philic Cyclization of Acyl Radicals onto NC Bond. New Synthesis of 2-Pyrrolidinones by Radical Carbonylation/Annulation Method

Nitrogen-philic Cyclization of Acyl Radicals onto NC Bond. New Synthesis of 2-Pyrrolidinones by Radical Carbonylation/Annulation Metho

Ring Opening and Expansion of Aziridines in a Silica−Water Reaction Medium

Ring-opening reactions of N-tosylaziridines with water-soluble nucleophiles proceeded in a silica−water reaction medium. The system is applicable to a ring expansion of an aziridine with potassium thiocyanate, leading to a thiazolidine derivative

Lactone Synthesis Based on Atom Transfer Carbonylation

Five- to seven-membered lactones were prepared from ω-hydroxyalkyl iodides and CO by atom transfer carbonylation without the need for transition metal catalysts. The reaction proceeds via a hybrid radical/ionic mechanism in which the intramolecular alcoholysis of an ω-hydroxyacyl iodide, arising from atom transfer carbonylation, leads to the lactone