5 research outputs found

    Ethno-Medicinal Uses and Agro-Biodiversity of Barmana Region in Bilaspur District of Himachal Pradesh, Northwestern Himalaya

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    India is one of the richest countries in traditional knowledge, because of its ambient biodiversity, variety of habitats and rich ethnic divergence. Thus we have had well established local health tradition still relevant in indigenous healthcare system. The paper provides first hand information on the agro-biodiversity and ethno-medicinal uses of the area. In the present study 50 species belonging to 37 genera and 17 families i.e. Shrub (1 spp.), tree (1 spp.), herb (48 spp.) were recorded under the agro-biodiversity region of the area. The utilization pattern of the species indicated that leaves of 22 species, stem of 1 species and seeds of 23 species, whole part of 11 species, tubers and flowers of 4 species, fruits of 18 species, each are used. 6 species were Indian origins, while others were non-native to Indian Himalayan Region

    Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

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    Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

    Perioperative anxiolysis and analgesic effect after premedication with melatonin and pregabalin in total hip arthroplasty under spinal anaesthesia: A prospective comparative trial

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    Background: Preoperative anxiety plays a critical role in post-operative pain response and other outcomes. Melatonin is a naturally secreted hormone which has anxiolytic, sedative, and analgesic properties. Pregabalin, analogue of gabapentin which has property of anxiolytic and analgesic effects. Materials and Methods: Total 96 patients undergoing total hip arthroplasty, divided into 3 groups of 32 each and were given placebo (group I), melatonin 6 mg (group II), and pregabalin 150 mg (group III). Anxiety level, postoperative pain score, sedation level and duration as well as characteristics of spinal anaesthesia were assessed with other vital parameters. Results: Group I showed an increment in the anxiety score from baseline whereas in group II and group III, there was a decline in pre-operative anxiety score from baseline at all the periods of observation and more significantly in group III. Visual analogue scale (VAS) score and total dose of rescue analgesia were highest in group I, but group II and group III were comparable to each other. However, the durations of spinal anaesthesia and motor blockade showed a statistically significant difference with maximum duration in group III followed by II and then I. The level of sedation among the three groups were comparable at all the periods of observation. Conclusions: Pregabalin was found better for perioperative anxiolysis, post-operative analgesia and for prolongation of duration of spinal anaesthesia when compared to melatonin

    Application of GIS, Multi-Criteria Decision-Making Techniques for Mapping Groundwater Potential Zones: A Case Study of Thalawa Division, Sri Lanka

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    Groundwater resources are depleting due to phenomena such as significant climate change and overexploitation. Therefore, it is essential to estimate water production and identify potential groundwater zones. An integrated conceptual framework comprising GIS and the analytical hierarchy process (AHP) has been applied for the present study to identify groundwater potential areas in the Thalawa division of Sri Lanka. The criteria, including rainfall, soil types, slope, stream density, lineament density, geology, geomorphology, and land use, were taken into account as the most contributing factors when identifying the groundwater zones. Weights were allocated proportionally to the eight thematic layers according to their importance. Hierarchical ranking and final normalized weighting of these determinants were performed using the pairwise comparison matrix (PCM) available in AHP. Based on the results obtained, the groundwater potential zone (GWPZ) was classified into three regions: low potentiality (33.4%), moderate potentiality (55.8%), and high potentiality (10.6%). Finally, the zoning map was compared to find consistency with field data on groundwater discharge and depth taken from 18 wells in the division. The results revealed that the GIS-multi-criteria decision-making (MCDM) approach brings about noticeably better results, which can support groundwater resource planning and sustainable use in the research area

    One stop mycology

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