3,581 research outputs found
Essential countability of treeable equivalence relations
We establish a dichotomy theorem characterizing the circumstances under which
a treeable Borel equivalence relation E is essentially countable. Under
additional topological assumptions on the treeing, we in fact show that E is
essentially countable if and only if there is no continuous embedding of E1
into E. Our techniques also yield the first classical proof of the analogous
result for hypersmooth equivalence relations, and allow us to show that up to
continuous Kakutani embeddability, there is a minimum Borel function which is
not essentially countable-to-one
Borel homomorphisms of smooth σ-ideals
Given a countable Borel equivalence relation E on a Polish space, let IE denote the σ-ideal generated by the Borel partial transversals of E. We show that there is a Borel homomorphism from IE to IF if and only if there is a smooth-to-one Borel homomorphism from a finite index Borel subequivalence relation of E to F. As a corollary, we see that IE is homogeneous in the sense of Zapletal (2007, Forcing Idealized, Preprint) if and only if E is hyperfinite. Using this, we prove that all Σ1 2 sets and Σ1 1 quasi-orders are Borel on Borel reducible to the quasi-order of Borel homomorphism on the class of inhomogeneous Π1 1 on Σ11 σ-ideals
Capitalist discourse, subjectivity and Lacanian psychoanalysis
This paper studies how subjectivity in capitalist culture can be characterized. Building on Lacan’s later seminars XVI, XVII, XVIII, and XIX, the author first outlines Lacan’s general discourse theory, which includes four characteristic discourses: the discourse of the master, the discourse of the university, the discourse of the hysteric and the discourse of the analyst. Next, the author explores the subjectivity and the mode of dealing with jouissance and semblance, which is entailed in a fifth type of discourse, the capitalist discourse, discussed by Lacan (1972). Indeed, like the other discourses that Lacan discerns, the discourse of the capitalist can be thought of as a mode of dealing with the sexual non-rapport. It is argued that in the case of neurosis the discourse of the capitalist functions as an attempt to ignore the sexual non-rapport and the dimension of the unconscious. Psychosis, by contrast, is marked by an a priori exclusion from discourse. In that case, consumerist ways of relating to the other might offer a semblance, and thus the possibility of inventing a mode of relating to the other. Two clinical vignettes are presented to illustrate this perspective: one concerning the neurotic structure and one concerning the psychotic structure
Algorithms Used to Update State Soil Survey
While seasonal weather can be the difference between a good and a bad harvest, it is the soil that moderates the long-term productivity of a field. The inherent properties of soils are vital to know when it comes to management practices on any agricultural landscape
Syn-orogenic high-temperature crustal melting: Geochronological and Nd-Sr-Pb isotope constraints from basement-derived granites (Central Damara Orogen, Namibia)
Major and trace element and Nd, Sr and Pb isotope data from c. 550 Ma-old gray granites and c. 510 Ma-old red leucogranites of the high-grade central part of the Damara orogen (Namibia) indicate a dominantly deep crustal origin. Moderately peraluminous gray granites are isotopically evolved (initial epsilon(Nd): C. - 17) and were likely derived from meta-igneous sources with late Archean to Paleoproterozoic crustal residence ages. Based on a comparison with experimental results, the granites were derived by partial melting of a granodioritic biotite gneiss at c. 900-950 degrees C and less than 10 kbar. Slightly peraluminous red leucogranites are also isotopically evolved (initial epsilon(Nd): - 15 to - 18) but have undergone extensive crystal fractionation coupled with minor contamination of mid crustal meta-pelitic material. Major and trace element data do not support closed-system fractional crystallization processes for all samples, however, some chemical features underline the importance of crystal fractionation processes especially for the leucogranites. Isotope data do not support mixing of different crust-derived melts or assimilation of crustal rocks by a mafic magma on a large scale. For the gray granites, unradiogenic Pb isotope compositions with substantial variation in Pb-207/Pb-204 at almost constant (206)pb/(204)pb, strongly negative epsilon(Nd) values and moderately radiogenic Sr isotope compositions argue for an undepleted nature of the source. High Rb/Sr ratios of the red leucogranites permit a comparison with the gray granites but similar initial ENd values indicate that the source of these granites is not fundamentally different to the source of the gray granites. The most acceptable model for both granite types involves partial melting of meta-igneous basement rocks of Archean to Proterozoic age. The consistency of the chemical data with a crustal anatectic origin and the observation that the gray granites intruded before the first peak of high-grade regional metamorphism suggests that they intruded simultaneously with crustal thickening. The red leucogranites are interpreted to be a result of crustal melting during the main peak of regional metamorphism. The heating events that promoted melting of fertile deep-crustal rocks might have been caused by the inferred high heat productivity of heat-producing radioactive elements (Th, U, K) together with crustal thickening during the main periods of orogen
Vegetation and Acidification
In this chapter, the impact of watershed acidification treatments on WS3 at the Fernow Experimental Forest (FEF) and at WS9 on vegetation is presented and summarized in a comprehensive way for the first time. WS7 is used as a vegetative reference basin for WS3, while untreated plots within WS9 are used as a vegetative reference for WS9. Bioindicators of acidification impacts that will be considered include several measures of tree and stand growth rates, foliar chemistry, bolewood chemistry, and herbaceous species composition and diversity. These studies enhance our understanding of the inter-relationships of changes in soil conditions caused by the acidification treatment and the condition of forest vegetation
Review of the BCI Competition IV
The BCI competition IV stands in the tradition of prior BCI competitions that aim to provide high quality neuroscientific data for open access to the scientific community. As experienced already in prior competitions not only scientists from the narrow field of BCI compete, but scholars with a broad variety of backgrounds and nationalities. They include high specialists as well as students. The goals of all BCI competitions have always been to challenge with respect to novel paradigms and complex data. We report on the following challenges: (1) asynchronous data, (2) synthetic, (3) multi-class continuous data, (4) session-to-session transfer, (5) directionally modulated MEG, (6) finger movements recorded by ECoG. As after past competitions, our hope is that winning entries may enhance the analysis methods of future BCIs.BMBF, 01IB001A, LOKI - Lernen zur Organisation komplexer Systeme der Informationsverarbeitung - Lernen im Kontext der SzenenanalyseBMBF, 01GQ0850, Bernstein Fokus Neurotechnologie - Nichtinvasive Neurotechnologie für Mensch-Maschine InteraktionEC/FP7/224631/EU/Tools for Brain-Computer Interaction/TOBIEC/FP7/216886/EU/Pattern Analysis, Statistical Modelling and Computational Learning 2/PASCAL2BMBF, 01GQ0420, Verbundprojekt: Bernstein-Zentrum für Neural Dynamics, Freiburg - CNDFBMBF, 01GQ0761, Bewegungsassoziierte Aktivierung - Dekodierung bewegungsassoziierter GehirnsignaleBMBF, 01GQ0762, Bewegungsassoziierte Aktivierung - Gehirn- und Maschinenlerne
Seeking legitimacy through CSR: Institutional Pressures and Corporate Responses of Multinationals in Sri Lanka
Arguably, the corporate social responsibility (CSR) practices of multinational enterprises (MNEs) are influenced by a wide range of both internal and external factors. Perhaps most critical among the exogenous forces operating on MNEs are those exerted by state and other key institutional actors in host countries. Crucially, academic research conducted to date offers little data about how MNEs use their CSR activities to strategically manage their relationship with those actors in order to gain legitimisation advantages in host countries. This paper addresses that gap by exploring interactions between external institutional pressures and firm-level CSR activities, which take the form of community initiatives, to examine how MNEs develop their legitimacy-seeking policies and practices. In focusing on a developing country, Sri Lanka, this paper provides valuable insights into how MNEs instrumentally utilise community initiatives in a country where relationship-building with governmental and other powerful non-governmental actors can be vitally important for the long-term viability of the business. Drawing on neo-institutional theory and CSR literature, this paper examines and contributes to the embryonic but emerging debate about the instrumental and political implications of CSR. The evidence presented and discussed here reveals the extent to which, and the reasons why, MNEs engage in complex legitimacy-seeking relationships with Sri Lankan institutions
Properties of stellar generations in Globular Clusters and relations with global parameters
ABRIDGED) We revise the formation of Galactic GCs by adding the detailed
chemical composition of their different stellar generations (from 1200 giants
in 19 GCs) to their global parameters. We propose to identify as GCs those
showing the Na-O anticorrelation, and we classify the GCs according to
kinematics and location in the Galaxy in disk/bulge, inner, and outer halo. We
find that the LF of GCs is fairly independent of their population, suggesting
that it is imprinted by the formation mechanism, and only marginally affected
by the ensuing evolution. We show that a large fraction of the primordial
population should have been lost by the proto-GCs. The extremely low Al
abundances found for the primordial population of massive GCs indicate a very
fast enrichment process before the formation of the primordial population. We
suggest a scenario for the formation of GCs including at least 3 main phases:
i) the formation of a precursor population (likely due to the interaction of
cosmological structures similar to those leading to dwarf spheroidals, but
residing at smaller Rgc, with the early Galaxy or with other structures), ii)
which triggers a large episode of star formation (the primordial population),
and iii) the formation of the current GC, mainly within a cooling flow formed
by the slow winds of a fraction of the primordial population. The precursor
population is very effective in raising the metal content in massive and/or
metal poor (mainly halo) clusters, while its role is minor in small and/or
metal rich (mainly disk) ones. Finally, we use PCA and multivariate relations
to study the phase of metal-enrichment from 1st to 2nd generation. Most of the
chemical signatures of GCs may be ascribed to a few parameters, the most
important being [Fe/H], mass, and age of the cluster, with the location within
the Galaxy also playing some role.Comment: 24 pages (+2 pages of bibliography and 5 of Appendix), 19 figures,
accepted for publication on Astronomy and Astrophysic
The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development
Despite multiple publications on potential therapies for neuromuscular diseases (NMD) in cell and animal models only a handful reach clinical trials. The ability to prioritise drug development according to objective criteria is particularly critical in rare diseases with large unmet needs and a limited numbers of patients who can be enrolled into clinical trials. TREAT-NMD Advisory Committee for Therapeutics (TACT) was established to provide independent and objective guidance on the preclinical and development pathway of potential therapies (whether novel or repurposed) for NMD. We present our experience in the establishment and operation of the TACT. TACT provides a unique resource of recognized experts from multiple disciplines. The goal of each TACT review is to help the sponsor to position the candidate compound along a realistic and well-informed plan to clinical trials, and eventual registration. The reviews and subsequent recommendations are focused on generating meaningful and rigorous data that can enable clear go/no-go decisions and facilitate longer term funding or partnering opportunities. The review process thereby acts to comment on viability, de-risking the process of proceeding on a development programme. To date TACT has held 10 review meeting and reviewed 29 program applications in several rare neuromuscular diseases: Of the 29 programs reviewed, 19 were from industry and 10 were from academia; 15 were for novel compounds and 14 were for repurposed drugs; 16 were small molecules and 13 were biologics; 14 were preclinical stage applications and 15 were clinical stage applications. 3 had received Orphan drug designation from European Medicines Agency and 3 from Food and Drug Administration. A number of recurrent themes emerged over the course of the reviews and we found that applicants frequently require advice and education on issues concerned with preclinical standard operating procedures, interactions with regulatory agencies, formulation, repurposing, clinical trial design, manufacturing and ethics. Over the 5 years since its establishment TACT has amassed a body of experience that can be extrapolated to other groups of rare diseases to improve the community's chances of successfully bringing new rare disease drugs to registration and ultimately to marke
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