A matching-adjusted indirect comparison of acalabrutinib versus zanubrutinib in relapsed or refractory chronic lymphocytic leukemia

Video abstract for our matching-adjusted indirect comparison of acalabrutinib versus zanubrutinib in relapsed or refractory chronic lymphocytic leukemia</p

Supplementary document for Single-Shot, High-Repetition Rate Carrier-Envelope-Phase Detection of Ultrashort Laser Pulses - 6563371.pdf

Supplemental Documen

Additional file 2: of Delineation of the population genetic structure of Culicoides imicola in East and South Africa

A table of estimates of genetic diversity of the microsatellite markers per population. The table describes the genetic diversity of the markers. Significant Hardy-Weinberg equilibrium (P < 0.05) tests are in BOLD. The expected gene diversity (He) varied from (0.2–0.94) while the observed heterozygosity (Ho) ranged from (0.125–1.0). Putative null alleles were identified at some loci in some populations using Microchecker. The null alleles were not locus specific. Ho- Observed heterozygosity; He- Expected heterozygosity; PHWE- Probability of Hardy-Weinberg equilibrium; FIS- Inbreeding coefficient; Nallele- Null allele; n- number of Samples (XLS 29 kb

Single-Shot, High-Repetition Rate Carrier-Envelope-Phase Detection of Ultrashort Laser Pulses

We propose a single-shot, high-repetition rate measurement scheme of the Carrier-Envelope Phase offset of ultrashort laser pulses. The spectral fringes resulting from f-2f nonlinear interferometry, encoding the Carrier-Envelope-Phase, are evaluated completely optically via optical Fourier transform. For demonstration, the Carrier-Envelope-Phase of a 200 kHz, few-cycle OPCPA laser system was measured employing an interferometer as a periodic optical filter. The proposed method shows excellent agreement with simultaneous measurement of the spectral fringes by a fast line-scan camera

Additional file 1: of Delineation of the population genetic structure of Culicoides imicola in East and South Africa

A summary of the C. imicola markers designed to the flanking regions of the microsatellite repeats with the type of repeats. The table provides a list of a total of 169 primer pairs predicted to anneal to a unique single pair read. The motif type that the primer represents is also indicated (XLS 41 kb

Compression of CEP-stable multi-mJ laser pulses down to 4 fs in long hollow fibers

Carrier envelope phase stable 4 fs near-IR pulses with 3 mJ energy were generated by spectral broadening of circularly polarized 8 mJ pulses in a differentially pumped 2 m long composite stretched exible hollow ber. The pulses were characterized using both second-harmonic generation frequency-resolved optical gating (SHG-FROG) and SHG d-scan method

Characterizing ultrashort laser pulses with second harmonic dispersion scans

The dispersion scan (d-scan) technique has emerged as a simple-to-implement characterization method for ultrashort laser pulses. D-scan traces are intuitive to interpret and retrieval algorithms that are both fast and robust have been developed to obtain the spectral phase and the temporal pulse profile. Here, we give a review of the d-scan technique based on second harmonic generation. We describe and compare recent implementations for the characterization of few- and multi-cycle pulses as well as two different approaches for recording d-scan traces in single-shot, thus showing the versatility of the technique

Single-shot d-scan technique for ultrashort laser pulse characterization using transverse second-harmonic generation in random nonlinear crystals

We demonstrate a novel dispersion-scan (d-scan) scheme for single-shot temporal characterization of ultrashort laser pulses. The novelty of this method relies on the use of a highly dispersive crystal featuring antiparallel nonlinear domains with a random distribution and size. This crystal, capable of generating a transverse second-harmonic signal, acts simultaneously as the dispersive element and the nonlinear medium of the d-scan device. The resulting in-line architecture makes the technique very simple and robust, allowing the acquisition of single-shot d-scan traces in real time. In addition, the technique can be further simplified by avoiding the need of dispersion pre-compensation. The retrieved pulses are in very good agreement with independent FROG measurements. We also apply the new single-shot d-scan to a TW-class laser equipped with a programmable pulse shaper, obtaining an excellent agreement between the applied and the d-scan retrieved dispersions

Additional file 1: of Review of ten-years presence of Aedes albopictus in Spain 2004–2014: known distribution and public health concerns

Historical record of the first detections of Aedes albopictus in municipalities of Spain. The bibliographical reference is included or it is considered as new record if this information was still unpublished. The reference number is related to the list of references of main document. (PDF 169 kb

Compact 200 kHz HHG source driven by a few-cycle OPCPA

We present efficient high-order harmonic generation (HHG) based on a high-repetition rate, few-cycle, near infrared (NIR), carrier-envelope phase stable, optical parametric chirped pulse amplifier (OPCPA), emitting 6fs pulses with 9{\mu}J pulse energy at 200kHz repetition rate. In krypton, we reach conversion efficiencies from the NIR to the extreme ultraviolet (XUV) radiation pulse energy on the order of ~10^{-6} with less than 3{\mu}J driving pulse energy. This is achieved by optimizing the OPCPA for a spatially and temporally clean pulse and by a specially designed high-pressure gas target. In the future, the high efficiency of the HHG source will be beneficial for high-repetition rate two-colour (NIR-XUV) pumpprobe experiments, where the available pulse energy from the laser has to be distributed economically between pump and probe pulses