Study characteristics based on those taking part in wave 5 (non-imputed).

*<p>Heavy drinker = more than 14 (women) or 21 (men) units per week.</p>**<p>Based on the UK Departments of Health recommendations of 2.5 hours of moderate or 1.25 hours of vigorous activity per week for 18–64 year olds.</p

Regression results for the five biomarkers modelled against birthweight and leg length.

*<p>p≤0.05;</p>**<p>p≤0.001.</p><p>Unadjusted: models include sex and birth status (singleton or twin).</p><p>Adjusted: models include unadjusted model plus: alcohol, smoking consumption, BMI, physical activity.</p

Additional file 2: of Social patterning in grip strength and in its association with age; a cross sectional analysis using the UK Household Longitudinal Study (UKHLS)

Age terms regressed on grip strength stratified by advantaged or disadvantaged SEP. (DOCX 25 kb

Association of dichotomous obesity measures with GHQ-12 by age: the dominant role of physical health.

<p>The graphs present predicted differences in mental health functioning between obese/non-obese by age estimated when previous models (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148561#pone.0148561.g002" target="_blank">Fig 2</a>) were further adjusted for (a) socio-economic characteristics, marital status and smoking (“without health”; solid lines with shaded area representing the 95%CI) and (b) for all the previous including the full set of physical health conditions (“full model”; dashed lines with spike plots representing the 95%CI). These associations were obtained by linear combinations of the main obesity coefficients and the age-obesity interactions (linear and quadratic interactions in case of BMI-obesity; linear, quadratic and cubic interactions in case of BF%-obesity and abdominal obesity) across different ages.</p

Association of adiposity measures with mental health functioning in UKHLS (waves 2–3, 5/2010-7/2013): Basic model^a.

<p>Association of adiposity measures with mental health functioning in UKHLS (waves 2–3, 5/2010-7/2013): Basic model<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148561#t002fn005" target="_blank">^a</a>.</p

Association of continuous adiposity measures with mental health functioning by age: Basic model.

<p>The graphs present associations of adiposity measures with mental health functioning by age estimated by augmenting basic models (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148561#pone.0148561.t002" target="_blank">Table 2</a>) with polynomial interactions of age with adiposity measures (linear and quadratic interactions in case of BMI; linear, quadratic and cubic interactions in case of WC). These associations were obtained by linear combinations of the main adiposity coefficients and the age-adiposity interactions across different ages (solid lines; shaded area: 95% confidence intervals).</p

Association of dichotomous obesity measures with mental health functioning by age: Basic model.

<p>The graphs present predicted differences in mental health functioning between obese/non-obese by age estimated by augmenting basic models (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148561#pone.0148561.t002" target="_blank">Table 2</a>) with polynomial interactions of age with obesity measures (linear and quadratic interactions in case of BMI-obesity measures; linear, quadratic and cubic interactions in case of BF%-obesity and abdominal obesity). These results were obtained by linear combinations of the main obesity coefficients and the age-obesity interactions across different ages (solid lines; shaded area: 95% confidence intervals).</p

Contribution of each physical health condition to the association between obesity and GHQ-12 at specific ages.

<p>Contribution of each physical health condition to the association between obesity and GHQ-12 at specific ages.</p

Self-rated health before and after adjustment, men.

<p>Figure 5 shows the predicted coefficients for self-rated health from marginal models for working class (relative to Salariat) for men for the entire sample (red line) and for 20 countries in the European Social Survey. Models include the base model, adjusting for financial strain, adjusting labour force status and adjusting for both labour force status and financial strain.</p

Participant characteristics for the analysis sample of UKHLS (waves 2–3, 5/2010-7/2013) by age group^a.

<p>Participant characteristics for the analysis sample of UKHLS (waves 2–3, 5/2010-7/2013) by age group<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148561#t001fn002" target="_blank">^a</a>.</p