Positive selection sites analysis using SLAC, FEL, IFEL and REL methods.

<p>Positive selection sites analysis using SLAC, FEL, IFEL and REL methods.</p

Phylogenetic analysis of the whole segment sequences of L, M, and S segments of 122 SFTSV strains.

<p>The maximum likelihood trees were constructed by using MEGA 5.02 software (<a href="http://www.megasoftware.net/" target="_blank">http://www.megasoftware.net/</a>). SFTSV was classified into 5 lineages labeled as A, B, C, D, and E by each genome segment. GenBank accession number and strain name were labeled on each branch. Bootstrap values ≧70 were labeled at nodes. Scale bar represented nucleotide substitutions per site.</p

Posterior mean and 95% HPDs of the substitution rates estimated from the actual data sets and the 5 tip-date randomizations for the each data set.

<p>Substitution rates on the left for each data set were estimated from the actual data sets. Substitution rates on the right for each data set were estimated from the randomized data sets. The mean rates estimated for the data sets were significantly different from those estimated from the randomized data sets.</p

Time-scaled Bayesian MCC phylogenetic tree based on concatenated SFTSV complete genome sequences.

<p>Tree nodes were annotated with posterior probability values (right), estimated median dates of time to most recent common ancestor (TMRCA) and 95% confidence interval of TMRCA (above). Lineages (A, B, C, D and E) were marked with different colors. SFTSV strain names were labeled on each branch. Horizontal axis indicated time in years.</p

Gene-specific global dN/dS ratios estimated using SLAC method.

<p>Gene-specific global dN/dS ratios estimated using SLAC method.</p

Correlation coefficients of air pollutants across 25 districts.

<p>Abbreviations: PM₁₀, particles with aerodynamic diameter 10 µm or less; SO₂, sulfur dioxide; NO₂, nitrogen dioxide; CO, carbon monoxide; O₃, ozone.</p><p>*<i>p</i><0.05.</p

Adjusted OR and 95% CIs of respiratory diseases with respect to ambient air pollutants (2006–2008) among children with allergic predisposition (n = 4135)^†.

†<p>Models were adjusted for the variables with asterisks in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022470#pone-0022470-t004" target="_blank">table 4</a>.</p>‡<p>OR were scaled to the interquartile range for each pollutant (31 µg/m³ for PM₁₀, 21 µg/m³ for SO₂, 10 µg/m³ for NO₂, 1001 µg/m³ for CO, and 23 µg/m³ for O₃).</p

Adjusted odds ratios (OR) for personal and household covariates associated with respiratory morbidity.

<p>*<i>p</i><0.15;</p><p>**<i>p</i><0.05.</p><p>Items with asterisks are included in the final adjustment model for this measurement. These items are adjusted for each other; remaining variables are adjusted only for the footnoted items, as well as for districts.</p

Adjusted OR and 95% CIs of respiratory diseases with respect to ambient air pollutants (2006–2008) among children without allergic predisposition (n = 26004)^†.

†<p>Models were adjusted for the variables with asterisks in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022470#pone-0022470-t004" target="_blank">table 4</a>.</p>‡<p>OR were scaled to the interquartile range for each pollutant (31 µg/m³ for PM₁₀, 21 µg/m³ for SO₂, 10 µg/m³ for NO₂, 1001 µg/m³ for CO, and 23 µg/m³ for O₃).</p

Difference Between Measured and Predicted Values Based on the Validation Subset.

*<p>Data are presented as mean of difference (predicted-measured) ±95% CI (confidence interval) of difference, and <i>P</i> value.</p