Data_Sheet_1_Association between oxidative balance score and metabolic syndrome and its components in US adults: a cross-sectional study from NHANES 2011–2018.CSV

BackgroundMetabolic syndrome (MetS) is a global health concern that threatens human well-being. The oxidative balance score (OBS) is a tool to identify the level of oxidative stress that is correlated with MetS risk. However, association between OBS and MetS and its components has not been reported.MethodsThis cross-sectional study included adult individuals with complete OBS and MetS data from National Health and Nutrition Examination Survey (NHANES) 2011–2018. A weighted logistic regression analysis was conducted to identify the association of the total, dietary, and lifestyle OBS scores with MetS. Subgroup analyses and restricted cubic splines were used to further explore associations.ResultsIn total, 10,025 eligible adult individuals (51.48% were males at a median age of 46 years) were included, with a MetS prevalence of 29.98%. In fully adjusted model, higher total OBS was associated with reduced risk of MetS (Q3 vs. Q1: odds ratio [OR] = 0.57, 95% confidence interval [CI], 0.46–0.71, p ConclusionThis study suggests a strong association between the OBS and MetS and its components. Our data indicated that a higher OBS score was correlated with a decreased risk of MetS and its components in a nonlinear manner. Hence, the OBS may serve as an effective marker for identifying individuals with MetS, with a higher score indicating a predominance of more antioxidants.</p

Image_1_Association between oxidative balance score and metabolic syndrome and its components in US adults: a cross-sectional study from NHANES 2011–2018.TIF

BackgroundMetabolic syndrome (MetS) is a global health concern that threatens human well-being. The oxidative balance score (OBS) is a tool to identify the level of oxidative stress that is correlated with MetS risk. However, association between OBS and MetS and its components has not been reported.MethodsThis cross-sectional study included adult individuals with complete OBS and MetS data from National Health and Nutrition Examination Survey (NHANES) 2011–2018. A weighted logistic regression analysis was conducted to identify the association of the total, dietary, and lifestyle OBS scores with MetS. Subgroup analyses and restricted cubic splines were used to further explore associations.ResultsIn total, 10,025 eligible adult individuals (51.48% were males at a median age of 46 years) were included, with a MetS prevalence of 29.98%. In fully adjusted model, higher total OBS was associated with reduced risk of MetS (Q3 vs. Q1: odds ratio [OR] = 0.57, 95% confidence interval [CI], 0.46–0.71, p ConclusionThis study suggests a strong association between the OBS and MetS and its components. Our data indicated that a higher OBS score was correlated with a decreased risk of MetS and its components in a nonlinear manner. Hence, the OBS may serve as an effective marker for identifying individuals with MetS, with a higher score indicating a predominance of more antioxidants.</p

Table_1_Association between oxidative balance score and metabolic syndrome and its components in US adults: a cross-sectional study from NHANES 2011–2018.DOCX

BackgroundMetabolic syndrome (MetS) is a global health concern that threatens human well-being. The oxidative balance score (OBS) is a tool to identify the level of oxidative stress that is correlated with MetS risk. However, association between OBS and MetS and its components has not been reported.MethodsThis cross-sectional study included adult individuals with complete OBS and MetS data from National Health and Nutrition Examination Survey (NHANES) 2011–2018. A weighted logistic regression analysis was conducted to identify the association of the total, dietary, and lifestyle OBS scores with MetS. Subgroup analyses and restricted cubic splines were used to further explore associations.ResultsIn total, 10,025 eligible adult individuals (51.48% were males at a median age of 46 years) were included, with a MetS prevalence of 29.98%. In fully adjusted model, higher total OBS was associated with reduced risk of MetS (Q3 vs. Q1: odds ratio [OR] = 0.57, 95% confidence interval [CI], 0.46–0.71, p ConclusionThis study suggests a strong association between the OBS and MetS and its components. Our data indicated that a higher OBS score was correlated with a decreased risk of MetS and its components in a nonlinear manner. Hence, the OBS may serve as an effective marker for identifying individuals with MetS, with a higher score indicating a predominance of more antioxidants.</p

Image_2_Association between oxidative balance score and metabolic syndrome and its components in US adults: a cross-sectional study from NHANES 2011–2018.TIF

BackgroundMetabolic syndrome (MetS) is a global health concern that threatens human well-being. The oxidative balance score (OBS) is a tool to identify the level of oxidative stress that is correlated with MetS risk. However, association between OBS and MetS and its components has not been reported.MethodsThis cross-sectional study included adult individuals with complete OBS and MetS data from National Health and Nutrition Examination Survey (NHANES) 2011–2018. A weighted logistic regression analysis was conducted to identify the association of the total, dietary, and lifestyle OBS scores with MetS. Subgroup analyses and restricted cubic splines were used to further explore associations.ResultsIn total, 10,025 eligible adult individuals (51.48% were males at a median age of 46 years) were included, with a MetS prevalence of 29.98%. In fully adjusted model, higher total OBS was associated with reduced risk of MetS (Q3 vs. Q1: odds ratio [OR] = 0.57, 95% confidence interval [CI], 0.46–0.71, p ConclusionThis study suggests a strong association between the OBS and MetS and its components. Our data indicated that a higher OBS score was correlated with a decreased risk of MetS and its components in a nonlinear manner. Hence, the OBS may serve as an effective marker for identifying individuals with MetS, with a higher score indicating a predominance of more antioxidants.</p

Additional file 1 of Interleukin-36 is overexpressed in human sepsis and IL-36 receptor deletion aggravates lung injury and mortality through epithelial cells and fibroblasts in experimental murine sepsis

Additional file 1. Figure S1 IL-36R and IL-36 subtypes mRNA expression in blood samples of sepsis patients (n = 18) compared with normal controls (n = 34) based on the reanalysis of a published dataset (GSE69063). Data in A, B, C are representative of 0, 1, 3 h post arrival. Data are shown as mean ± SEM; NS, not significant; *P < 0.05, **P < 0.01 by two-tailed Student’s t test

Liquid Metal Nanoparticles Physically Hybridized with Cellulose Nanocrystals Initiate and Toughen Hydrogels with Piezoionic Properties

Liquid metal (LM) particles can serve as initiators, functional fillers, and cross-linkers for hydrogels. Herein, we show that cellulose nanocrystals (CNCs) stabilize LM particles in aqueous solutions, such as those used to produce hydrogels. The CNC-coated LM particles initiate free-radical polymerization to form poly­(acrylic acid) (PAA) hydrogel with exceptional propertiesstretchability ∼2000%, excellent toughness ∼1.8 MJ/m3, mechanical resilience, and efficient self-healingrelative to cross-linked PAA networks polymerized using conventional molecular initiators. FTIR spectroscopy, rheology, and mechanical measurements suggest that physical bonds between PAA and both Ga3+ and LM-CNC particles contribute to the excellent mechanical properties. The gels are used to sense a wide range of strains, such as those associated with human motion, via changes in resistance through the gel. The sensitivity at low strains enables monitoring subtle physiological signals, such as pulse. Without significantly compromising the toughness, soaking the gels in salt solution brings about high ionic conductivity (3.8 S/m), enabling them to detect touch via piezoionic principles; the anions in the gel have higher mobility than cations, resulting in significant charge separation (current ∼30 μA, ∼10 μA/cm2) through the gel in response to touch. These attractive properties are promising for wearable sensors, energy harvesters, and self-powered ionic touch panels

Correction to Strengthening Alginate/Polyacrylamide Hydrogels Using Various Multivalent Cations

Correction to Strengthening Alginate/Polyacrylamide Hydrogels Using Various Multivalent Cation

Puncture-Resistant Hydrogel: Placing Molecular Complexes Along Phase Boundaries

Trendy advances in electric cars and wearable electronics triggered growing awareness in device lethality/survivability from accidents. A divergent design in protection calls for high stress resistance, large ductility, as well as efficient energy dissipation, all from the device itself, while keeping the weight-specific device performance to its premium. Unfortunately, the polymer electrolyte or the ductile elastomer lacks a mechanistic design to resist puncture or tear at a high stress level. Here, we designed molecular complexes along phase boundaries to mitigate the damages by placing these mechanically strong complexes along the phase boundaries or between two immiscible polymers. This puncture-resistant gel, dubbed as gel-nacre, is able to survive a few challenging incidents, including a 400 MPa puncture from a sharp nail, a 1 cm steel ball traveling at 540 km/h, and attempted rupture on stitched samples

Puncture-Resistant Hydrogel: Placing Molecular Complexes Along Phase Boundaries

Trendy advances in electric cars and wearable electronics triggered growing awareness in device lethality/survivability from accidents. A divergent design in protection calls for high stress resistance, large ductility, as well as efficient energy dissipation, all from the device itself, while keeping the weight-specific device performance to its premium. Unfortunately, the polymer electrolyte or the ductile elastomer lacks a mechanistic design to resist puncture or tear at a high stress level. Here, we designed molecular complexes along phase boundaries to mitigate the damages by placing these mechanically strong complexes along the phase boundaries or between two immiscible polymers. This puncture-resistant gel, dubbed as gel-nacre, is able to survive a few challenging incidents, including a 400 MPa puncture from a sharp nail, a 1 cm steel ball traveling at 540 km/h, and attempted rupture on stitched samples

Puncture-Resistant Hydrogel: Placing Molecular Complexes Along Phase Boundaries

Trendy advances in electric cars and wearable electronics triggered growing awareness in device lethality/survivability from accidents. A divergent design in protection calls for high stress resistance, large ductility, as well as efficient energy dissipation, all from the device itself, while keeping the weight-specific device performance to its premium. Unfortunately, the polymer electrolyte or the ductile elastomer lacks a mechanistic design to resist puncture or tear at a high stress level. Here, we designed molecular complexes along phase boundaries to mitigate the damages by placing these mechanically strong complexes along the phase boundaries or between two immiscible polymers. This puncture-resistant gel, dubbed as gel-nacre, is able to survive a few challenging incidents, including a 400 MPa puncture from a sharp nail, a 1 cm steel ball traveling at 540 km/h, and attempted rupture on stitched samples